-
1.发明公开MICRONEEDLE-ARRAY PRODUCTION DEVICE, MICRONEEDLE-ARRAY PRODUCTION METHOD, AND ARTICLE PROVIDED WITH MICRONEEDLE ARRAY 审中-公开微型阵列生产装置，微型阵列生产方法和提供微型阵列的物品
公开(公告)号：EP3235537A1
公开(公告)日：2017-10-25
申请号：EP15869935.5
申请日：2015-12-14
发明人： YAMADA, Shinya , CHIYAMA, Masateru , AKITA, Kensaku , UENO, Takako , IDE, Yuko , NAGAI, Sachi , AKAO, Osanobu , ONO, Ichiro , TAKADA, Kanji
CPC分类号： B29C39/24 , A61M37/00 , A61M37/0015 , A61M2037/0053 , B05B12/122 , B29C65/004 , B29L2031/7544 , B81B1/00
摘要： A product having a microneedle array is provided wherein the composition distribution has been adjusted with good accuracy. A droplet-delivery apparatus (10) of a microneedle-array manufacturing apparatus (1) is configured capable of delivering, to each recessed part, droplets of a raw-material liquid in a prescribed amount that is less than the capacity of the recessed part. An aligning apparatus (20) can align the relative position of the droplet-delivery apparatus (10) and a mold (80) such that the droplets from the droplet-delivery apparatus (10) are caused to land in each of the recessed parts. The droplet-delivery apparatus (10) delivers a plurality of the droplets to each of the recessed parts; and the aligning apparatus aligns the relative position of the droplet-delivery apparatus and the mold such that a second droplet lands in each of the recessed parts on the center part side of a first droplet.
摘要翻译： 提供了具有微针阵列的产品，其中组合物分布已经以良好的精度进行了调整。 微针阵列制造装置（1）的液滴输送装置（10）被构造成能够将小于凹部的容量的规定量的原料液的液滴输送到每个凹部 。 对准装置（20）可以使液滴输送装置（10）和模具（80）的相对位置对齐，使得来自液滴输送装置（10）的液滴落在每个凹陷部分中。 液滴输送装置（10）将多个液滴输送至每个凹陷部分; 并且对准装置将液滴输送设备和模具的相对位置对齐，使得第二液滴落在第一液滴的中心部分侧的每个凹陷部分中。
-
2.发明公开
公开(公告)号：EP3117867A1
公开(公告)日：2017-01-18
申请号：EP14885596.8
申请日：2014-03-12
发明人： TAKADA, Kanji , ONO, Ichiro
CPC分类号： A61M37/0015 , A61K9/0014 , A61K38/00 , A61K38/1825 , A61M2037/0023 , A61M2037/0046 , A61M2202/07 , A61M2202/097
摘要： The problem of the invention is to provide a microneedle preparation administration apparatus that prevents overdosing caused by duplicate administration within a treatment range of skin, more reliably administers a prescribed dose of a growth factor at an intended optional depth in the dermis, exhibits an intended effect, and avoids pigmentation side effects. The solution to the problem is a microneedle preparation administration apparatus comprising: a guide tube; a pedestal in which at least a part thereof including a front end surface is housed within the guide tube and slides in length direction; and driving means for driving the pedestal toward a front end part of the guide tube, and microneedle preparations being to be attached to the front end surface of the pedestal, and the microneedle preparations being to be pressed out from a front end part of the guide tube, wherein the microneedle preparation has a first portion having a tip end part and containing an objective substance, and a second portion having a bottom part and not containing the objective substance, and the front end surface of the pedestal is struck on skin at a collision pressure of 30 N to 200 N per 1 cm 2 .
摘要翻译： 该发明的问题是提供一种微针制备给药装置并防止过量给药通过重复给药皮肤的治疗范围内造成的，更可靠地在负责管理的生长因子的预定用量在真皮预期任意深度，在预期的效果展品 ，避免色素沉着的副作用。 到该溶液问题是微针制备给药装置，包括：引导管; 基座，其中至少包括其前端面的一部分被引导管和在长度方向上滑动，内坐落; 和驱动装置，用于驱动所述基座向所述引导管的前端部，以及微针制剂是将被安装在台座的前端面，和微针的制剂是为从导向件的前端部压出 管，worin微针制备具有包括前端部和目标物质的含，和具有第二部分的底部部分和不包含目标物质，和台座的前端面在被击打在皮肤上的第一部分 的30 N至200N碰撞压力每1cm 2。
-
3.发明公开MICRONEEDLE PATCH, METHOD FOR MANUFACTURING SAME, AND APPARATUS FOR MANUFACTURING MICRONEEDLE ARRAY 审中-公开MICRONEEDLE PATCH，其制造方法及用于制造MICRONEEDLE ARRAY的装置
公开(公告)号：EP3235538A1
公开(公告)日：2017-10-25
申请号：EP15869985.0
申请日：2015-12-15
发明人： ONO, Ichiro , YAMADA, Shinya , CHIYAMA, Masateru , AKITA, Kensaku , UENO, Takako , IDE, Yuko , NAGAI, Sachi , AKAO, Osanobu , TAKADA, Kanji
CPC分类号： B29C39/24 , A61M37/00 , A61M37/0015 , A61M2037/0053 , B05B12/122 , B29C65/004 , B29L2031/7544 , B81B1/00
摘要： A microneedle patch with which a treatment is reliably completed in a short time when a microneedle is administered into skin or mucous membrane is provided. A microneedle patch (100F) includes a base member (101) and a plurality of microneedles (103g) supported by the base member (101). Each microneedle (103g) includes a top-section layer (104) comprising a biologically active substance to be inserted in dermis (310), and an intermediate layer (106) provided between the top-section layer (104) and the base member (101), having a composition having breaking strength weaker than breaking strength of a composition of the top-section layer (104), and having a thickness of 5 µm and 100 µm inclusive.
摘要翻译： 本发明提供一种微针贴片，该微针贴片在向皮肤或粘膜给予微针时能够在短时间内可靠地完成治疗。 微针贴片（100F）包括基座构件（101）和由基座构件（101）支撑的多个微针（103g）。 每个微针103g包括包含待插入真皮310中的生物活性物质的顶层部分104以及设置在顶层部分104和基底部件103之间的中间层106。 101），其组成具有断裂强度弱于顶部层（104）的组成的断裂强度，并且具有5μm和100μm（包括端值）的厚度。
-
公开(公告)号：EP3235537B1
公开(公告)日：2019-08-07
申请号：EP15869935.5
申请日：2015-12-14
发明人： YAMADA, Shinya , CHIYAMA, Masateru , AKITA, Kensaku , UENO, Takako , IDE, Yuko , NAGAI, Sachi , AKAO, Osanobu , ONO, Ichiro , TAKADA, Kanji
-
5.发明公开
公开(公告)号：EP2641614A1
公开(公告)日：2013-09-25
申请号：EP12783484.4
申请日：2012-06-28
发明人： TAKADA, Kanji , ONO, Ichiro
IPC分类号： A61K45/00 , A61K31/713 , A61K38/00 , A61K47/36 , A61P17/00 , A61P17/02 , A61P17/14 , A61M37/00
CPC分类号： A61M37/0015 , A61K9/0021 , A61K9/70 , A61K38/1825 , A61K45/06 , A61M2037/0046
摘要： A problem to be solved of the present invention is to provide a drug formulation and a method of administering an active ingredient which allow the active ingredient to be delivered evenly into the site of action in the skin with high efficiency while ensuring stability of the active ingredient over a long time, and which are easily handled and are less stressful for patients. Mean for solving the problem is a microneedle assembly formulation for skin treatment comprising a platform and a plurality of conical or pyramidal microneedles formed on the platform containing a base composed of a bio-soluble and thread-forming polymer substance and an objective substance retained in the base, wherein the objective substance is a substance effective for prevention or treatment of skin senescence, or treatment of skin scar.
摘要翻译： 本发明要解决的问题是提供一种药物制剂和一种给药活性成分的方法，其允许活性成分以高效率均匀地递送到皮肤中的作用部位，同时确保活性成分的稳定性 很长一段时间，而且容易处理，对患者来说压力更小。 用于解决该问题的意思是用于皮肤处理的微针组装配方，其包括平台和在平台上形成的多个锥形或金字塔形微针，所述微针包含由生物可溶且形成线的聚合物物质组成的基底和保留在 其中目标物质是有效用于预防或治疗皮肤衰老或治疗皮肤瘢痕的物质。
-
-
-
-
搜索结果
5 条记录 (耗时 0.01 秒)
