MICRONEEDLE-ARRAY PRODUCTION DEVICE, MICRONEEDLE-ARRAY PRODUCTION METHOD, AND ARTICLE PROVIDED WITH MICRONEEDLE ARRAY
    1.
    发明公开
    MICRONEEDLE-ARRAY PRODUCTION DEVICE, MICRONEEDLE-ARRAY PRODUCTION METHOD, AND ARTICLE PROVIDED WITH MICRONEEDLE ARRAY 审中-公开
    微型阵列生产装置,微型阵列生产方法和提供微型阵列的物品

    公开(公告)号:EP3235537A1

    公开(公告)日:2017-10-25

    申请号:EP15869935.5

    申请日:2015-12-14

    IPC分类号: A61M37/00 B81B1/00

    摘要: A product having a microneedle array is provided wherein the composition distribution has been adjusted with good accuracy. A droplet-delivery apparatus (10) of a microneedle-array manufacturing apparatus (1) is configured capable of delivering, to each recessed part, droplets of a raw-material liquid in a prescribed amount that is less than the capacity of the recessed part. An aligning apparatus (20) can align the relative position of the droplet-delivery apparatus (10) and a mold (80) such that the droplets from the droplet-delivery apparatus (10) are caused to land in each of the recessed parts. The droplet-delivery apparatus (10) delivers a plurality of the droplets to each of the recessed parts; and the aligning apparatus aligns the relative position of the droplet-delivery apparatus and the mold such that a second droplet lands in each of the recessed parts on the center part side of a first droplet.

    摘要翻译: 提供了具有微针阵列的产品,其中组合物分布已经以良好的精度进行了调整。 微针阵列制造装置(1)的液滴输送装置(10)被构造成能够将小于凹部的容量的规定量的原料液的液滴输送到每个凹部 。 对准装置(20)可以使液滴输送装置(10)和模具(80)的相对位置对齐,使得来自液滴输送装置(10)的液滴落在每个凹陷部分中。 液滴输送装置(10)将多个液滴输送至每个凹陷部分; 并且对准装置将液滴输送设备和模具的相对位置对齐,使得第二液滴落在第一液滴的中心部分侧的每个凹陷部分中。

    METHOD FOR PRODUCING TRANSDERMAL PATCH AND TRANSDERMAL PATCH
    2.
    发明公开
    METHOD FOR PRODUCING TRANSDERMAL PATCH AND TRANSDERMAL PATCH 审中-公开
    VERFAHREN ZUR HERSTELLUNG EINES TRANSDERMALEN PFLASTERS UND TRANSDERMALES PFLASTER

    公开(公告)号:EP2995343A1

    公开(公告)日:2016-03-16

    申请号:EP14794706.3

    申请日:2014-04-22

    IPC分类号: A61M37/00

    摘要: A low cost transdermal patch, which comprises water soluble microneedles and has good performance, and a method of manufacturing the same are provided. A transdermal patch (1 E) comprises a microneedle sheet (310), which comprises a plurality of water soluble microneedles (311), moisture permeable sheet (320), wherethrough water vapor passes, and a reinforcing film (30E). The reinforcing film (30E) is adhered, by an adhesive layer (35) having an adhesive strength less than that of an adhesive layer (322), onto an outer surface (320b) of the moisture permeable sheet (320), which is the side opposite the skin opposing surface (320a). The reinforcing film (30E) includes a water vapor barrier sheet (31), which blocks the passage of water vapor through at least a first area (Ar1), and a removable portion (32) around the water vapor barrier sheet (31). The removable portion (32) is configures such that it can be separated from and peeled off the water vapor barrier sheet (31).

    摘要翻译: 提供了包含水溶性微针并具有良好性能的低成本透皮贴片及其制造方法。 透皮贴片(1E)包括微针片(310),其包括多个水溶性微针(311),通过水蒸汽通过的透湿片(320)和增强膜(30E)。 通过具有比粘合剂层(322)的粘合强度小的粘合剂层(35)将增强膜(30E)粘附到可透湿片材(320)的外表面(320b)上,其是 侧面与皮肤相对表面(320a)相对。 增强膜(30E)包括阻挡水蒸气通过至少第一区域(Ar1)的水蒸汽阻隔片(31)和围绕水蒸气阻挡片(31)的可移除部分(32)。 可拆卸部分(32)构造成使得其可以与水蒸气阻隔片(31)分离并从其上剥离。

    THIN FILM FORMING DEVICE
    3.
    发明公开
    THIN FILM FORMING DEVICE 失效
    VORRICHTUNG ZUR ERZEUGUNG DUNNER FILME

    公开(公告)号:EP0887693A1

    公开(公告)日:1998-12-30

    申请号:EP97907301.2

    申请日:1997-03-13

    IPC分类号: G02F1/1337 B41F17/14

    CPC分类号: B41F5/24 B41F11/00 B41F13/21

    摘要: A thin film formation apparatus comprises a printing roll 3 having an elastic letterpress 31 of resin or rubber fitted at a part of a surface of a cylinder part 30 and, an intaglio roll 4 rotating while being faced to the printing roll 3 thereby transferring ink to a surface of the elastic letter-press 31 through touch with the printing roll 3. The thin film formation apparatus further comprises a pair of printing roll side contact bodies 300 on a drum portion or a rotating shaft of the printing roll, and a pair of intaglio roll side contact bodies 400 on a drum portion or a rotating shaft of the intaglio roll, the printing roll side contact bodies 300 and the intaglio roll side contact bodies 400 continuing to contact with each other at least before and during the contact of the elastic letterpress 31 with the intaglio roll 4 to form a thin film of uniform film thickness.

    摘要翻译: 薄膜形成装置包括印刷辊3,其具有装配在圆筒部30的表面的一部分处的树脂或橡胶的弹性凸版31,以及与打印辊3相对地旋转从而将墨转印到 弹性字母压机31的表面通过与印刷辊3接触而形成。薄膜形成装置还包括在印刷辊的鼓部分或旋转轴上的一对印刷辊侧接触体300和一对 至少在弹性体的接触之前和期间,印刷辊侧接触体300和凹版辊侧接触体400在鼓部分或转轴上的凹版辊侧接触体400彼此连续接触, 凸版31与凹版辊4形成均匀薄膜厚度的薄膜。

    PACKAGING BODY FOR SHEET WITH CONICAL PROJECTIONS AND METHOD FOR MANUFACTURING SAME
    4.
    发明公开
    PACKAGING BODY FOR SHEET WITH CONICAL PROJECTIONS AND METHOD FOR MANUFACTURING SAME 审中-公开
    用包装体叶子及其制造锥体状突起和方法

    公开(公告)号:EP3108924A1

    公开(公告)日:2016-12-28

    申请号:EP15767856.6

    申请日:2015-03-25

    摘要: A conical-projections-sheet packaging body (1) includes a conical-projections sheet (23), a conical-projections forming sheet (7), and a sealing sheet (9). The conical-projections sheet (23) includes a substrate (23a) and a plurality of conical projections (23b) formed on a surface (23c) of the substrate (23a). The conical-projections forming sheet (7) has a plurality of conical-recess parts (33a), which is used to form the plurality of conical projections (23b) and wherein the plurality of conical projections (23b) is disposed. The conical-projections forming sheet (7) protects the conical projections (23b) in a state wherein the plurality of conical projections (23b) is tightly adhered to the surface (23c) of the substrate (23a). The sealing sheet (9), by being fixed to the conical-projections forming sheet (7), seals the conical-projections sheet (23) between the conical-projections forming sheet (7) and the sealing sheet (9).

    摘要翻译: 锥形凸块片包装体(1)包括一锥形突起片(23),锥形凸块形成片(7),和一个密封片材(9)。 所述锥形突起片(23)包括基板(23A)和形成在基板(23A)的表面(23℃)上的锥形突起(23B)的复数。 形成片(7)的锥形突起具有其被用于形成锥形突起(23B)的多元性和worin圆锥形突起(23B)设置的许多锥形槽部分33a中,全部多个。 形成片(7)的锥形突起保护圆锥形突起(23B)的状态下,锥形worin突起(23B)的多元性被牢固地附着于基片(23A)的表面(23℃)。 通过固定于形成片的锥形突起的密封片(9)(7)密封所述锥形突起之间的锥形突起片(23)形成片(7)与密封片(9)。

    METHOD FOR MANUFACTURING PACKAGING FOR CONICAL PROTRUSION SHEET
    5.
    发明公开
    METHOD FOR MANUFACTURING PACKAGING FOR CONICAL PROTRUSION SHEET 审中-公开
    制造锥形凸块包装的方法

    公开(公告)号:EP3115078A1

    公开(公告)日:2017-01-11

    申请号:EP15769382.1

    申请日:2015-03-13

    IPC分类号: A61M37/00

    摘要: To protect a plurality of conical projections of a conical-projections sheet. A method of manufacturing a conical-projections-sheet packaging body 1 including: a step of forming a plurality of conical-recess parts 34b on a conical-projections forming sheet 34; a step of forming, by supplying a conical-projections material to the conical-projections forming sheet 34, a conical-projections sheet 23 including a base sheet 23a and a plurality of conical projections 23b formed on a surface of the base sheet 23a and disposed inside the plurality of conical-recess parts 34b; a step of forming a plurality of sets of the conical-projections forming sheets 34 and the conical-projections sheets 23 by punching out the conical-projections forming sheets 34 and the conical-projections sheets 23; and a step of using a package member 5 to package a set of the conical-projections sheets 23 and the conical-projections forming sheets 34 tightly adhered to one another.

    摘要翻译: 为了保护锥形投影片的多个圆锥形突起。 一种制造圆锥形凸起片包装体1的方法,包括:在圆锥形凸起形成片34上形成多个圆锥形凹部34b的步骤; 通过向锥形突起形成片34提供锥形突起材料而形成锥形突起片23的步骤,所述锥形突起片包括基片23a和形成在基片23a的表面上的多个圆锥形突起23b, 在多个圆锥形凹部34b内; 通过冲压锥形突起形成片34和锥形突起片23形成多组圆锥形突起形成片34和锥形突起片23的步骤; 以及使用包装部件5来包装彼此紧密粘附的一组锥形突起片23和圆锥形突起形成片34的步骤。

    MICRONEEDLE PATCH, METHOD FOR MANUFACTURING SAME, AND APPARATUS FOR MANUFACTURING MICRONEEDLE ARRAY
    7.
    发明公开
    MICRONEEDLE PATCH, METHOD FOR MANUFACTURING SAME, AND APPARATUS FOR MANUFACTURING MICRONEEDLE ARRAY 审中-公开
    MICRONEEDLE PATCH,其制造方法及用于制造MICRONEEDLE ARRAY的装置

    公开(公告)号:EP3235538A1

    公开(公告)日:2017-10-25

    申请号:EP15869985.0

    申请日:2015-12-15

    IPC分类号: A61M37/00 B81B1/00

    摘要: A microneedle patch with which a treatment is reliably completed in a short time when a microneedle is administered into skin or mucous membrane is provided. A microneedle patch (100F) includes a base member (101) and a plurality of microneedles (103g) supported by the base member (101). Each microneedle (103g) includes a top-section layer (104) comprising a biologically active substance to be inserted in dermis (310), and an intermediate layer (106) provided between the top-section layer (104) and the base member (101), having a composition having breaking strength weaker than breaking strength of a composition of the top-section layer (104), and having a thickness of 5 µm and 100 µm inclusive.

    摘要翻译: 本发明提供一种微针贴片,该微针贴片在向皮肤或粘膜给予微针时能够在短时间内可靠地完成治疗。 微针贴片(100F)包括基座构件(101)和由基座构件(101)支撑的多个微针(103g)。 每个微针103g包括包含待插入真皮310中的生物活性物质的顶层部分104以及设置在顶层部分104和基底部件103之间的中间层106。 101),其组成具有断裂强度弱于顶部层(104)的组成的断裂强度,并且具有5μm和100μm(包括端值)的厚度。