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1.发明公开
公开(公告)号：EP2323970A1
公开(公告)日：2011-05-25
申请号：EP09804572.7
申请日：2009-08-05
申请人： Novartis AG
发明人： BEATTIE, David , COLSON, Anny-Odile , CULSHAW, Andrew James , ROONEY, Lisa , STANLEY, Emily , SVIRIDENKO, Lilya
IPC分类号： C07C233/79 , C07C255/58 , C07C311/39 , C07D213/74 , C07D213/75 , C07D213/84 , C07D277/42 , A61K31/166 , A61K31/427 , A61K31/44 , A61P1/00
CPC分类号： A61K31/5377 , A61K31/166 , A61K31/415 , A61K31/426 , A61K31/44 , A61K31/4406 , A61K45/06 , C07C233/79 , C07C255/58 , C07C311/39 , C07C317/28 , C07C2601/14 , C07D209/08 , C07D213/74 , C07D213/82 , C07D213/84 , C07D215/38 , C07D231/12 , C07D231/16 , C07D231/38 , C07D231/56 , C07D233/61 , C07D233/64 , C07D239/42 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D261/14 , C07D277/04 , C07D277/42 , C07D295/135 , C07D401/04 , C07D401/12 , C07D403/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： There are described cyclohexyl amide derivatives useful as corticotropin releasing factor (CRF
1 ) receptor antagonists.-
2.发明授权
公开(公告)号：EP2531490B1
公开(公告)日：2014-10-15
申请号：EP11701824.2
申请日：2011-01-31
申请人： Novartis AG
IPC分类号： A61K31/4155 , A61P25/24 , C07D213/82 , C07D231/12 , C07D231/14 , C07D231/16 , C07D231/20 , C07D231/38 , C07D231/54 , C07D231/56 , C07D249/08 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D471/04 , C07D473/00 , C07D491/052 , C07C233/79
CPC分类号： C07D213/82 , C07C233/79 , C07C2601/14 , C07D231/12 , C07D231/14 , C07D231/16 , C07D231/20 , C07D231/38 , C07D231/54 , C07D231/56 , C07D249/08 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D471/04 , C07D473/00 , C07D491/052
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3.发明授权
公开(公告)号：EP2323970B1
公开(公告)日：2016-04-20
申请号：EP09804572.7
申请日：2009-08-05
申请人： Novartis AG
发明人： BEATTIE, David , COLSON, Anny-Odile , CULSHAW, Andrew James , ROONEY, Lisa , STANLEY, Emily , SVIRIDENKO, Lilya
IPC分类号： C07C233/79 , C07C255/58 , C07C311/39 , C07D213/74 , C07D213/75 , C07D213/84 , C07D277/42 , A61K31/166 , A61K31/427 , A61K31/44 , A61P1/00
CPC分类号： A61K31/5377 , A61K31/166 , A61K31/415 , A61K31/426 , A61K31/44 , A61K31/4406 , A61K45/06 , C07C233/79 , C07C255/58 , C07C311/39 , C07C317/28 , C07C2601/14 , C07D209/08 , C07D213/74 , C07D213/82 , C07D213/84 , C07D215/38 , C07D231/12 , C07D231/16 , C07D231/38 , C07D231/56 , C07D233/61 , C07D233/64 , C07D239/42 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D261/14 , C07D277/04 , C07D277/42 , C07D295/135 , C07D401/04 , C07D401/12 , C07D403/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D495/04
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4.发明公开PIPERIDIN-ACETAMIDE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY OR ALLERGIC DISEASES 审中-公开胡椒碱乙酰胺衍生物对炎症性疾病或过敏性痛苦的治疗
公开(公告)号：EP2125731A1
公开(公告)日：2009-12-02
申请号：EP08708328.3
申请日：2008-01-29
申请人： Novartis AG
IPC分类号： C07D211/70 , C07D403/12 , A61K31/41 , A61K31/4409 , A61K31/4439 , A61P11/00 , A61P29/00 , A61P17/00 , A61P37/08
CPC分类号： C07D211/70 , C07D401/12
摘要： A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, wherein R1 and R2 independently are (C6-18)aryl or (C6-18)aryl(C1-6)alkyl one or morefold substituted by (C1-6)alkyl, C(1-6)aIkoxy, halo(C1-6)alkyl, halogen or unsubstituted or substituted heterocyclyl having 5 or 6 ring members and 1 to 4 heteroatoms selected from N, O, S.
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公开(公告)号：EP2531490A1
公开(公告)日：2012-12-12
申请号：EP11701824.2
申请日：2011-01-31
申请人： Novartis AG
IPC分类号： C07D213/82 , C07D231/12 , C07D231/14 , C07D231/16 , C07D231/20 , C07D231/38 , C07D231/54 , C07D231/56 , C07D249/08 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D471/04 , C07D473/00 , C07D491/052 , C07C233/79
CPC分类号： C07D213/82 , C07C233/79 , C07C2601/14 , C07D231/12 , C07D231/14 , C07D231/16 , C07D231/20 , C07D231/38 , C07D231/54 , C07D231/56 , C07D249/08 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D471/04 , C07D473/00 , C07D491/052
摘要： There are described cyclohexyl amide derivatives useful as corticotropin releasing factor (CRF) receptor antagonists Formula (I).
摘要翻译： 描述了用作促肾上腺皮质素释放因子（CRF）受体拮抗剂式（I）的环己酰胺衍生物。
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