公开(公告)号：EP3180047B1

公开(公告)日：2018-10-24

申请号：EP15750729.4

申请日：2015-08-13

Applicant: Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) ,  Institut Químic de Sarrià CETS Fundació Privada

Inventor： ROSELL GRATACOS, Antoni ,  BORROS GÓMEZ, Salvador ,  GILABERT PORRES, Joan ,  MARTÍ MARTÍ, Sara ,  MONTES WORBOYS, Ana ,  RAMOS PÉREZ, Víctor ,  MOLINA MOLINA, María

IPC: A61L31/10 ,  A61L31/16 ,  C23C18/16 ,  C23C18/18 ,  C23C18/20 ,  B05D1/00 ,  A61L31/06

CPC classification number: A61L31/16 ,  A61F2/82 ,  A61L31/06 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/416 ,  A61L2300/624 ,  A61L2400/12 ,  A61L2420/02 ,  B05D1/36 ,  B05D1/60 ,  B05D1/62 ,  C23C16/06 ,  C23C16/50 ,  C23C18/166 ,  C23C18/1893 ,  C23C18/2086 ,  C08L83/04

Abstract: The invention relates to medical devices and, more in particular, to medical devices suitable for use as stents that contain an antimicrobial coating and, optionally, a drug customized to patients requirements. The invention also relates to methods for obtaining devices having the above features.

公开(公告)号：EP3373985A1

公开(公告)日：2018-09-19

申请号：EP16809569.3

申请日：2016-11-10

Applicant: 3M Innovative Properties Company

Inventor： YU, Ta-Hua ,  DEMIRGÖZ, Döne ,  LIU, Junkang J. ,  VEERARAGHAVAN, Badri ,  STEPANOVA, Narina Y.

IPC: A61L15/18 ,  A61L15/42 ,  A61L15/46

CPC classification number: A61L15/46 ,  A61L15/18 ,  A61L15/42 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/602 ,  A61L2400/12

Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface; a metal oxide layer, wherein the nanostructured surface is coated with the metal oxide layer and the metal oxide layer comprises a metal oxide; and a metal layer overlaying the metal oxide layer.

公开(公告)号：EP3373983A1

公开(公告)日：2018-09-19

申请号：EP16864816.0

申请日：2016-11-07

Applicant: Materials Modification Inc.

Inventor： KASTHURI, Rangan, Krishnaswamy ,  SRINIVAS, Sudarshan, Tirumalai

IPC: A61L15/16 ,  A61L15/18 ,  A61L15/20 ,  A61L15/42 ,  A61L15/44 ,  A61F13/00 ,  C01B33/40

CPC classification number: A61L15/18 ,  A61F13/00021 ,  A61F2013/00906 ,  A61L15/44 ,  A61L15/46 ,  A61L2300/104 ,  A61L2300/402 ,  A61L2300/404

Abstract: A multifunctional polymer-free clay products having a clay, a zwitterion, a silver compound, and, an analgesic. The multifunctional polymer-free clay product provides antimicrobial and pain relieving properties. Method of treatment of bums using the multifunctional polymer-tree clay product having antimicrobial and pain relieving properties. Methods of preparing multifunctional polymer-free clay products having a clay, a zwitterion, a silver compounds and, an analgesic.

公开(公告)号：EP3190881A4

公开(公告)日：2018-06-20

申请号：EP15840677

申请日：2015-09-09

Applicant: IASIS MOLECULAR SCIENCES ,  VACHON DAVID J ,  NORDAL SCOTT FRITHJOF ,  WALTERS DANA CHRISTOPHER

Inventor： VACHON DAVID JOHN ,  NORDAL SCOTT FRITHJOF ,  WALTERS DANA CHRISTOPHER

IPC: B01J39/19 ,  A01N25/08 ,  A01N25/10 ,  A61L15/46 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  B01J39/20 ,  B01J41/14

CPC classification number: B01J45/00 ,  A01N25/10 ,  A01N25/16 ,  A01N33/12 ,  A01N41/04 ,  A01N41/12 ,  A01N43/40 ,  A01N59/00 ,  A01N59/16 ,  A61H19/44 ,  A61K31/14 ,  A61K31/155 ,  A61K31/616 ,  A61K33/38 ,  A61K47/585 ,  A61L15/24 ,  A61L15/44 ,  A61L15/46 ,  A61L15/58 ,  A61L26/0066 ,  A61L26/0085 ,  A61L27/18 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/11 ,  A61L2300/206 ,  A61L2300/208 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/43 ,  A61L2300/606 ,  B01J39/19 ,  B01J39/20 ,  B01J41/14 ,  B65D65/40 ,  B65D65/42 ,  C08J3/12 ,  C08J9/365 ,  C08J2205/05 ,  C08J2325/02 ,  C08J2325/08 ,  C08J2375/04 ,  C08J2425/02 ,  C08J2425/08 ,  C08L23/12 ,  C08L57/06 ,  C08L63/00 ,  C08L75/04 ,  C08L83/04 ,  C09D5/14 ,  C09D5/1637 ,  C09D201/00 ,  C09J9/00 ,  C09J11/08 ,  C09J183/04 ,  G01N33/18 ,  G01N33/24 ,  G01N2033/245 ,  A01N47/44 ,  A01N59/20

Abstract: Biologically activated ion-exchange polymer salts are made by exchanging biologically active ionic agents onto ion-exchange polymers. The activated polymers are uniquely surface active and stable to thermal degradation and chemical and other forms of decomposition. The activated ion-exchange polymer salts may be processed and combined with polymer precursors using novel methods and materials to produce stable, biologically activated polymer composites, including antimicrobial and antifouling polymer composites.

公开(公告)号：EP3313458A1

公开(公告)日：2018-05-02

申请号：EP16736737.4

申请日：2016-06-29

Applicant: 3M Innovative Properties Company

Inventor： YU, Ta-Hua ,  LIU, Junkang Jacob ,  STEPANOVA, Narina Y. ,  VEERARAGHAVAN, Badri ,  DAVID, Moses M.

IPC: A61L15/18 ,  A61L15/46

CPC classification number: A61L15/44 ,  A61F13/00029 ,  A61F13/00063 ,  A61F13/00068 ,  A61L15/18 ,  A61L15/24 ,  A61L15/46 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2400/12 ,  A61L2420/02

Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer and a substrate having a nanostructured surface. The nanostructured surface is coated with a metal oxide layer and the metal oxide layer includes a metal oxide.

公开(公告)号：EP3291848A1

公开(公告)日：2018-03-14

申请号：EP16722511.9

申请日：2016-05-05

Applicant: 3M Innovative Properties Company

Inventor： YU, Ta-Hua ,  LIU, Junkang Jacob ,  STEPANOVA, Narina Y. ,  VEERARAGHAVAN, Badri ,  DAVID, Moses M.

IPC: A61L15/46

CPC classification number: A61L15/46 ,  A61K9/0014 ,  A61L2300/102 ,  A61L2300/104

Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer, an absorbent layer over-laying the occlusive layer, and a metal oxide layer overlaying the absorbent layer, wherein the metal oxide layer comprises a metal oxide and wherein the metal oxide layer comprises less than 40 wt. % non-oxidized metal.

公开(公告)号：EP2414565B1

公开(公告)日：2018-03-14

申请号：EP10712137.8

申请日：2010-03-30

Applicant: Accentus Medical Limited

Inventor： TURNER, Andrew, Derek

IPC: C25D11/26 ,  A61L27/04 ,  A61L27/32 ,  A61L27/54 ,  A61F2/28

CPC classification number: C25D11/26 ,  A61F2/28 ,  A61L27/04 ,  A61L27/32 ,  A61L27/54 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/02

Abstract: A metal object is treated to form an integral surface layer by: (a) immersing the metal object in an anodising electrolyte, and passivating the metal to form an anodised layer on the metal object; (b) continuing the application of a potential to modify the surface layer; (c) then treating the metal object with a chemical reducing agent so a hydrous metal oxide is formed; and (d) then contacting the metal object with a solution containing a biocidal material so as to incorporate biocidal material into the surface layer.

公开(公告)号：EP2414564B1

公开(公告)日：2018-03-14

申请号：EP10712135.2

申请日：2010-03-29

Applicant: Accentus Medical Limited

Inventor： SHAWCROSS, James, Timothy ,  LEWIS, David, Richard ,  TURNER, Andrew, Derek

IPC: C25D11/26 ,  A61L31/02 ,  A61L31/08 ,  A61L31/16

CPC classification number: C23C28/00 ,  A61L31/022 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/404 ,  C25D11/24 ,  C25D11/26

Abstract: Metal objects are treated by anodising (P, SE) the metal object in contact with an acidic solution, and then subjecting the anodised metal object to a reversed voltage (VR). The anodising is performed in two stages, firstly to passivate (P) with the formation of a surface layer, and secondly to form pits in this surface layer (SE). The second stage (SE) of anodising is performed at a lower voltage than the first stage (P). After the reversed voltage step (VR) the metal object is then contacted with a biocidal metal-containing solution. Biocidal metal is absorbed into the surface of the metal object, resulting in improved biocidal properties. The lower voltage of the second stage anodising (SE) results in reduced processing time.

公开(公告)号：EP2224970B1

公开(公告)日：2018-02-28

申请号：EP08848649.3

申请日：2008-11-12

Applicant: Medicoat AG

Inventor： GRUNER, Heiko ,  GRUNER, Philipp ,  TOURENNE, Francis

IPC: A61L27/32 ,  A61L27/54 ,  A61L27/42

CPC classification number: A61L27/32 ,  A61L27/54 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2400/18

公开(公告)号：EP3281614A1

公开(公告)日：2018-02-14

申请号：EP17180220.0

申请日：2017-07-07

Applicant: Datt Mediproducts Pvt. Ltd ,  Datt Life Science Pvt. Ltd

Inventor： Datt, Rajan ,  Kumar, Ramadhar ,  Pandey, Siddharth ,  Shrivastava, Pallavi

IPC: A61F13/00 ,  A61L15/32 ,  A61L15/20 ,  A61L15/40 ,  A61K36/82 ,  A61K36/9066 ,  A61K36/47

CPC classification number: A61K36/9066 ,  A61F13/00012 ,  A61F13/00017 ,  A61F2013/00638 ,  A61F2013/00646 ,  A61F2013/0091 ,  A61K9/7069 ,  A61K31/765 ,  A61K33/38 ,  A61K36/185 ,  A61K36/47 ,  A61K36/82 ,  A61K36/886 ,  A61K47/10 ,  A61K47/22 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K2236/33 ,  A61K2236/51 ,  A61K2236/53 ,  A61L15/18 ,  A61L15/20 ,  A61L15/225 ,  A61L15/32 ,  A61L15/40 ,  A61L15/425 ,  A61L15/44 ,  A61L15/585 ,  A61L2300/104 ,  A61L2300/30 ,  A61L2300/404 ,  A61L2300/62 ,  A61L2300/802 ,  A61K2300/00

Abstract: This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

Abstract translation: 本发明涉及一种用于治疗受损组织如人和动物皮肤伤口和溃疡的药物制剂以及制备方法。 这是一种多功能天然基质，用于治疗受损组织，这也涉及用于黑素瘤治疗的抗癌透皮贴剂。 此外，本发明还包括治疗阿尔茨海默氏症和多发性硬化症。 该组合物由草药，动物或合成生物相容性凝胶中或基质包被的或两者的水溶性纳米大小的植物药物非水溶剂提取物组成。 在其优选实施例中，该组合物用作治疗受损组织的局部装置。