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公开(公告)号：EP3972651A2
公开(公告)日：2022-03-30
申请号：EP20733328.7
申请日：2020-05-19
发明人： BURGER, Matthew, T. , CHANRION, Maia , COLLAND, Frédéric , CSEKEI, Marton , DELACOUR, Lea , DESOS, Patrice , GENESTE, Olivier , HENLIN, Jean-Michel , KOSTOVA, Vesela , KOTSCHY, Andras , MARAGNO, Ana, Leticia , MCNEILL, Eric , PALERMO, Mark, G. , ROCCHETTI, Francesca , STARCK, Jérôme , YU, Bing , ZHANG, Qiang , PROSZENYÁK, Ágnes , SIPOS, Szabolcs , CHEN, Zhuoliang , NAKAJIMA, Katsumasa , D'ALESSIO, Joseph, Anthony
IPC分类号： A61K47/68
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公开(公告)号：EP3972649A2
公开(公告)日：2022-03-30
申请号：EP20730922.0
申请日：2020-05-19
发明人： BURGER, Matthew, T. , CHANRION, Maia , COLLAND, Frédéric , CSEKEI, Marton , DELACOUR, Lea , DESOS, Patrice , GENESTE, Olivier , HENLIN, Jean-Michel , KOSTOVA, Vesela , KOTSCHY, Andras , MARAGNO, Ana, Leticia , MCNEILL, Eric , PALERMO, Mark, G. , ROCCHETTI, Francesca , STARCK, Jérôme , YU, Bing , ZHANG, Qiang , PROSZENYÁK, Ágnes , SIPOS, Szabolcs , CHEN, Zhuoliang , NAKAJIMA, Katsumasa , D'ALESSIO, Joseph, Anthony , BLANKENSHIP, John, William
IPC分类号： A61K47/68
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3.发明公开NEW HYDROXYACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开新的羟基衍生物，其制备方法和含有它们的药物组合物
公开(公告)号：EP3313849A1
公开(公告)日：2018-05-02
申请号：EP16731155.4
申请日：2016-06-22
发明人： SZLÁVIK, Zoltán , PACZAL, Attila , BÁLINT, Balázs , KOTSCHY, András , CHANRION, Maïa , GENESTE, Olivier , DAVIDSON, James Edward Paul , MURRAY, James Brooke , SIPOS, Szabolcs , PROSZENYÁK, Ágnes
IPC分类号： C07D495/04 , A61K31/519 , A61P35/00 , A61P37/00
CPC分类号： A61K31/519 , A61K31/215 , A61K31/381 , A61P35/00 , C07D495/04
摘要： wherein R1, R2, R3, R4, R5, R6, R7, R8, R14, A and n are as defined in the description.
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4.发明公开
公开(公告)号：EP4277892A1
公开(公告)日：2023-11-22
申请号：EP22700101.3
申请日：2022-01-11
发明人： STOKES, Stephen , BEDFORD, Simon , CHEN, I-Jen , DAVIDSON, James Edward Paul , DAVIES, Nicholas , GRAHAM, Christopher John , MCKENNA, Sean Martin , MEISSNER, Johannes W.G. , MURRAY, James , PARSONS, Rachel Jane , RAY, Stuart , SANDERS, Emma , WALMSLEY, Claire Louise , BROUGH, Paul Andrew , KOTSCHY, András , PROSZENYÁK, Ágnes , SINAI, Ádám , BÁLINT, Balázs Károly , CSÉKEI, Márton , ZWILLINGER, Márton , GARAMVÖLGYI, Rita , SIPOS, Szabolcs , KUN, Vilibald , SZABÓ, Zoltán , CHANRION, Maïa , ROCCHETTI, Francesca , COLLAND, Frédéric , MARAGNO, Ana Leticia , BRESSON, Laura
IPC分类号： C07D205/04 , C07C71/00 , C07D213/72 , C07D215/233 , C07D221/20 , C07D401/12 , C07D405/12 , C07D491/056 , C07D495/04 , A61K31/404 , A61P35/00 , C07C49/697 , C07C233/52 , C07C229/50 , C07C323/61
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5.发明公开NEW AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 有权新的氨基酸衍生物，它们的制备方法和含有它们的药物组合物
公开(公告)号：EP3313850A1
公开(公告)日：2018-05-02
申请号：EP16731158.8
申请日：2016-06-22
发明人： SZLÁVIK, Zoltán , SZABÓ, Zoltán , CSÉKEI, Márton , PACZAL, Attila , KOTSCHY, András , BRUNO, Alain , GENESTE, Olivier , CHEN, I-Jen , DAVIDSON, James Edward Paul , MURRAY, James Brooke , ONDI, Levente , RADICS, Gábor , SIPOS, Szabolcs , PROSZENYÁK, Ágnes , PERRON-SIERRA, Françoise , BÁLINT, Balázs
IPC分类号： C07D495/04 , A61K31/519 , A61P35/00 , A61P37/00
CPC分类号： C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R5, R6, R7, R12, X, Y, A, E and n are as defined in the description. Medicaments.
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公开(公告)号：EP3313817B1
公开(公告)日：2020-09-16
申请号：EP16730854.3
申请日：2016-06-22
发明人： BÁLINT, Balázs , CSÉKEI, Márton , SZABÓ, Zoltán , SZLÁVIK, Zoltán , KOTSCHY, András , CHANRION, Maïa , GENESTE, Olivier , CHEN, I-Jen , DAVIDSON, James Edward Paul , MURRAY, James Brooke , SIPOS, Szabolcs , ONDI, Levente , PROSZENYÁK, Ágnes
IPC分类号： C07D209/12 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04 , A61K31/381 , A61K31/4355 , A61K31/437 , A61P35/00
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公开(公告)号：EP3313850B1
公开(公告)日：2018-10-03
申请号：EP16731158.8
申请日：2016-06-22
发明人： SZLÁVIK, Zoltán , SZABÓ, Zoltán , CSÉKEI, Márton , PACZAL, Attila , KOTSCHY, András , BRUNO, Alain , GENESTE, Olivier , CHEN, I-Jen , DAVIDSON, James Edward Paul , MURRAY, James Brooke , ONDI, Levente , RADICS, Gábor , SIPOS, Szabolcs , PROSZENYÁK, Ágnes , PERRON-SIERRA, Françoise , BÁLINT, Balázs
IPC分类号： C07D495/04 , A61K31/519 , A61P35/00 , A61P37/00
CPC分类号： C07D495/04
摘要： Compounds of formula (I): wherein R1, R2, R5, R6, R7, R12, X, Y, A, E and n are as defined in the description. Medicaments.
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8.发明公开NEW BICYCLIC DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开新的二环衍生物，它们的制备方法和含有它们的药物组合物
公开(公告)号：EP3313817A1
公开(公告)日：2018-05-02
申请号：EP16730854.3
申请日：2016-06-22
发明人： BÁLINT, Balázs , CSÉKEI, Márton , SZABÓ, Zoltán , SZLÁVIK, Zoltán , KOTSCHY, András , CHANRION, Maïa , GENESTE, Olivier , CHEN, I-Jen , DAVIDSON, James Edward Paul , MURRAY, James Brooke , SIPOS, Szabolcs , ONDI, Levente , PROSZENYÁK, Ágnes
IPC分类号： C07D209/12 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04 , A61K31/381 , A61K31/4355 , A61K31/437 , A61P35/00
摘要： Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
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