公开(公告)号：EP1576136B1

公开(公告)日：2011-05-25

申请号：EP03794659.7

申请日：2003-09-05

申请人： Novozymes, Inc.

发明人： YAVER, Debbie ,  SLOMA, Alan

IPC分类号： C12Q1/18 ,  C12Q1/68 ,  A23J3/34

CPC分类号： C12Q1/6809 ,  A23J3/343 ,  C12Q1/18 ,  C12Q1/689 ,  C12Q2600/136 ,  C12Q2600/158

摘要： The present invention relates to arrays for bacterial gene expression profiling in response to treatment with antimicrobial compounds. Bacterial nucleic acid molecules are used as the hybridizable elements in various applications, such as arrays for gene expression profiling and for determining a mode of action for an antimicrobial compound. The present invention also relates to nucleic acid sequences which can be developed as targets for drug screening.

公开(公告)号：EP1537229B1

公开(公告)日：2013-09-11

申请号：EP03771884.8

申请日：2003-07-25

申请人： Novozymes, Inc.

发明人： TANG, Maria ,  SLOMA, Alan ,  STERNBERG, David ,  BEHR, Regine

IPC分类号： C12N1/12 ,  C12N1/20 ,  C12P21/06 ,  C07K14/32 ,  C12P19/00 ,  C12N9/02 ,  C12P1/04 ,  C12P21/02

CPC分类号： C12N9/0077 ,  C07K14/32 ,  C12P1/04 ,  C12P19/00 ,  C12P21/02

公开(公告)号：EP1056873B1

公开(公告)日：2010-03-31

申请号：EP99911012.5

申请日：1999-02-26

申请人： Novozymes, Inc.

发明人： WIDNER, William ,  SLOMA, Alan ,  THOMAS, Michael, D.

IPC分类号： C12N15/75 ,  C12N15/52 ,  C12N15/57 ,  C12N9/54 ,  C12N1/21

CPC分类号： C12N15/75

公开(公告)号：EP1576136A2

公开(公告)日：2005-09-21

申请号：EP03794659.7

申请日：2003-09-05

申请人： Novozymes, Inc.

发明人： YAVER, Debbie ,  SLOMA, Alan

IPC分类号： C12N1/00

CPC分类号： C12Q1/6809 ,  A23J3/343 ,  C12Q1/18 ,  C12Q1/689 ,  C12Q2600/136 ,  C12Q2600/158

摘要： The present invention relates to arrays for bacterial gene expression profiling in response to treatment with antimicrobial compounds. Bacterial nucleic acid molecules are used as the hybridizable elements in various applications, such as arrays for gene expression profiling and for determining a mode of action for an antimicrobial compound. The present invention also relates to nucleic acid sequences which can be developed as targets for drug screening.

公开(公告)号：EP1042457B1

公开(公告)日：2006-03-08

申请号：EP98956817.5

申请日：1998-11-13

申请人： Novozymes A/S ,  Novozymes, Inc. ,  Japan Tobacco Inc.

发明人： BLINKOVSKY, Alexander ,  BYUN, Tony, S. ,  KLOTZ, Alan, V. ,  SLOMA, Alan ,  BROWN, Kimberly ,  TANG, Maria ,  FUJII, Miko ,  MARUMOTO, Chigusa ,  KOFOD, Lene, Venke

IPC分类号： C12N9/48

CPC分类号： A23J3/34 ,  C12N9/48 ,  C12P21/06

摘要： The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.