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公开(公告)号：EP1668135B8
公开(公告)日：2012-03-21
申请号：EP04770714.6
申请日：2004-08-27
申请人： ORF Líftaekni hf.
CPC分类号： C12N15/8241 , C07K1/22 , C07K14/415 , C07K2319/20 , C07K2319/50 , C12N9/6424 , C12N15/62 , C12N15/8257 , C12P21/06
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公开(公告)号：EP4161955A1
公开(公告)日：2023-04-12
申请号：EP21734952.1
申请日：2021-06-07
申请人： ORF Líftaekni hf.
IPC分类号： C07K14/475 , A01H1/00 , C07K14/415 , C12N5/077
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3.发明授权ENHANCING ACCUMULATION OF HETEROLOGOUS POLYPEPTIDES IN PLANT SEEDS THROUGH TARGETED SUPPRESSION OF ENDOGENOUS STORAGE PROTEINS 有权提高异源多肽富集植物种子通过有针对性的抑制的内源贮藏蛋白
公开(公告)号：EP1668137B8
公开(公告)日：2012-03-21
申请号：EP04770716.1
申请日：2004-08-27
申请人： ORF Líftaekni hf.
发明人： ORVAR, Bjorn, Larus
CPC分类号： C07K14/4702 , C12N15/8234 , C12N15/8251 , C12N15/8257
摘要： The present invention relates to improved methods for increasing accumulation levels of heterologous proteins in plant seeds for molecular farming through targeted suppression of endogenous proteins that compete against the heterologous protein for limited resources, such as amino acids, ribosomal binding sites and portfolio of enzymes participating in translation and post-translational processing. Provided are methods to suppress expression of transcription factors in barley aquired for transcriptional activation of hordein genes, using either antisense 'inhibition' or double stranded RNA-induced RNA interferance or post transcriptional gene silencing (PTGS).
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4.发明授权A PROCESS FOR PROTEOLYTIC CLEAVAGE AND PURIFICATION OF RECOMBINANT PROTEINS PRODUCED IN PLANTS 有权方法蛋白水解切割和生产的植物中重组蛋白的纯化
公开(公告)号：EP1668136B8
公开(公告)日：2012-03-21
申请号：EP04770715.3
申请日：2004-08-27
申请人： ORF Líftaekni hf.
CPC分类号： C12N15/8241 , C07K1/22 , C07K14/415 , C07K2319/20 , C07K2319/50 , C12N9/6424 , C12N15/62 , C12N15/8257 , C12P21/06
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