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1.Mutant vesicular stomatitis viruses and use thereof 有权
标题翻译: Mutierte Viren dervesikulärenStomatitis und deren Verwendung公开(公告)号:EP2039773A1
公开(公告)日:2009-03-25
申请号:EP08168529.9
申请日:2004-03-29
IPC分类号: C12N15/86 , C07K14/145 , C12N7/04 , A61K39/205
CPC分类号: C07K14/005 , A61K35/766 , A61K39/12 , A61K39/205 , A61K39/39 , A61K48/00 , A61K2039/5254 , A61K2039/5256 , C07K2319/60 , C12N7/00 , C12N15/86 , C12N2760/20222 , C12N2760/20232 , C12N2760/20234 , C12N2760/20243 , C12N2760/20261 , C12N2830/00 , C12N2830/85
摘要: An oncolytic vesicular stomatitis virus (VSV) having a ΔM51 mutation in the matrix (M) protein for use in the treatment of cancer is provided.
摘要翻译: 提供了在用于治疗癌症的基质(M)蛋白中具有“M51突变”的溶瘤性水泡性口炎病毒(VSV)。
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公开(公告)号:EP2039773B1
公开(公告)日:2011-12-28
申请号:EP08168529.9
申请日:2004-03-29
IPC分类号: C12N15/86 , C07K14/145 , C12N7/04 , A61K39/205
CPC分类号: C07K14/005 , A61K35/766 , A61K39/12 , A61K39/205 , A61K39/39 , A61K48/00 , A61K2039/5254 , A61K2039/5256 , C07K2319/60 , C12N7/00 , C12N15/86 , C12N2760/20222 , C12N2760/20232 , C12N2760/20234 , C12N2760/20243 , C12N2760/20261 , C12N2830/00 , C12N2830/85
摘要: An oncolytic vesicular stomatitis virus (VSV) having a ”M51 mutation in the matrix (M) protein for use in the treatment of cancer is provided.
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