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公开(公告)号:EP3440098A1
公开(公告)日:2019-02-13
申请号:EP17722128.0
申请日:2017-04-06
发明人: JAYASINGHE, Lakmal , BRUCE, Mark , MCNEILL, Luke , NATHANI, Ramiz Iqbal , SINGH, Pratik Raj , WOOD, Neil Roger , YOUNG, Stephen Robert
IPC分类号: C07K14/435 , C12Q1/68 , G01N27/447
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公开(公告)号:EP2875128B8
公开(公告)日:2020-06-24
申请号:EP13740348.1
申请日:2013-07-18
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公开(公告)号:EP2875152B1
公开(公告)日:2019-10-09
申请号:EP13740351.5
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , MISCA, Mihaela
IPC分类号: C12Q1/6869 , C12N9/14
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公开(公告)号:EP2836506A1
公开(公告)日:2015-02-18
申请号:EP13711464.1
申请日:2013-03-15
IPC分类号: C07K14/435 , C12Q1/00
CPC分类号: C07K14/43536 , C07K2319/55 , C12Q1/6869 , G01N27/447
摘要: The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using lysenin.
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公开(公告)号:EP2836506B1
公开(公告)日:2017-04-19
申请号:EP13711464.1
申请日:2013-03-15
IPC分类号: C07K14/435 , C12Q1/00
CPC分类号: C07K14/43536 , C07K2319/55 , C12Q1/6869 , G01N27/447
摘要: The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using lysenin.
摘要翻译: 本发明涉及赖sen素的突变形式。 本发明还涉及使用赖sen素的分析物表征。
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公开(公告)号:EP2875152A1
公开(公告)日:2015-05-27
申请号:EP13740351.5
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , MISCA, Mihaela
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C07K2319/00 , C12N9/14 , C12Y306/04 , C12Q2521/513 , C12Q2522/101 , C12Q2565/631
摘要: The invention relates to methods using constructs comprising a helicase and an additional polynucleotide binding moiety. The helicase is attached to the polynucleotide binding moiety and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
摘要翻译: 本发明涉及使用包含解旋酶和另外的多核苷酸结合部分的构建体的方法。 解旋酶连接到多核苷酸结合部分,并且构建体具有控制多核苷酸运动的能力。 该构建体可以用于控制多核苷酸的运动,并且对于测序多核苷酸特别有用。
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公开(公告)号:EP2875128A1
公开(公告)日:2015-05-27
申请号:EP13740348.1
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , ALVES, David , BOWEN, Rebecca , MILTON, John
摘要: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
摘要翻译: 本发明涉及具有减少的来自多核苷酸的结合的修饰的解旋酶。 解旋酶可用于控制多核苷酸的运动,并且特别可用于测序多核苷酸。
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公开(公告)号:EP3741847A1
公开(公告)日:2020-11-25
申请号:EP20171363.3
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , ALVES, David , BOWEN, Rebecca , MILTON, John
摘要: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
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公开(公告)号:EP3097204B1
公开(公告)日:2020-07-08
申请号:EP14776897.2
申请日:2014-09-10
发明人: BOWEN, Rebecca Victoria , BROWN, Clive Gavin , BRUCE, Mark , HERON, Andrew John , WALLACE, Elizabeth Jayne , WHITE, James , LLOYD, Joseph Hargreaves , ALVES, David Antoni , CAPROTTI, Domenico , JAYASINGHE, Lakmal , MCNEILL, Luke , MILTON, John , PUGLISI, Antonino , SOEROES, Szabolcs
IPC分类号: C12Q1/6869
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公开(公告)号:EP3192804B1
公开(公告)日:2019-08-28
申请号:EP17157441.1
申请日:2013-03-15
IPC分类号: C07K14/435 , C12Q1/00
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