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公开(公告)号:EP3423486A1
公开(公告)日:2019-01-09
申请号:EP17710372.8
申请日:2017-03-02
IPC分类号: C07K16/12 , C12Q1/68 , G01N33/483
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公开(公告)号:EP3204511A1
公开(公告)日:2017-08-16
申请号:EP15784437.4
申请日:2015-10-06
发明人: JAYASINGHE, Lakmal , WALLACE, Elizabeth Jayne , PUGH, Jonathan Bankes , HAMBLEY, Richard George , WOOD, Neil Roger , HERON, Andrew John , WHITE, James
CPC分类号: C12Q1/6869 , B01L3/502761 , B01L2200/0663 , B01L2300/0636 , B01L2300/0896 , C07K14/35 , C12Q1/68 , G01N33/48721 , C12Q2565/607 , C12Q2565/631
摘要: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
摘要翻译: 本发明涉及Msp的突变形式。 本发明还涉及使用Msp进行多核苷酸表征。
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公开(公告)号:EP3892627A1
公开(公告)日:2021-10-13
申请号:EP21163695.6
申请日:2018-05-03
发明人: JAYASINGHE, Lakmal Nishantha , WALLACE, Elizabeth Jayne , SINGH, Pratik Raj , HAMBLEY, Richard George , JORDAN, Michael , REMAUT, Han
IPC分类号: C07K14/245 , C12Q1/6869
摘要: Provided is a method of characterising a polynucleotide using a transmembrane pore, wherein the pore is a double pore comprising a first CsgG pore, or a homologue thereof, and a second CsgG pore, or a homologue thereof.
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公开(公告)号:EP3877547A1
公开(公告)日:2021-09-15
申请号:EP19801616.4
申请日:2019-11-07
发明人: REMAUT, Han , VAN DER VERREN, Sander, Egbert , VAN GERVEN, Nani , JAYASINGHE, Lakmal, Nishantha , WALLACE, Elizabeth Jayne , SINGH, Pratik, Raj , HAMBLEY, Richard, George , JORDAN, Michael, Robert , KILGOUR, John, Joseph , HERON, Andrew, John
IPC分类号: C12Q1/6869
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公开(公告)号:EP2875128B8
公开(公告)日:2020-06-24
申请号:EP13740348.1
申请日:2013-07-18
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公开(公告)号:EP2875152B1
公开(公告)日:2019-10-09
申请号:EP13740351.5
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , MISCA, Mihaela
IPC分类号: C12Q1/6869 , C12N9/14
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公开(公告)号:EP3423487A1
公开(公告)日:2019-01-09
申请号:EP17710373.6
申请日:2017-03-02
IPC分类号: C07K16/12 , C12Q1/68 , G01N33/483
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公开(公告)号:EP3137490A1
公开(公告)日:2017-03-08
申请号:EP15720770.5
申请日:2015-05-01
CPC分类号: C12Q1/6869 , C07K14/35 , C12Q2563/157 , C12Q2565/631
摘要: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
摘要翻译: 本发明涉及Msp的突变形式。 本发明还涉及使用Msp的多核苷酸表征。
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公开(公告)号:EP3741847A1
公开(公告)日:2020-11-25
申请号:EP20171363.3
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , ALVES, David , BOWEN, Rebecca , MILTON, John
摘要: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
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