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公开(公告)号:EP3207155B1
公开(公告)日:2019-06-05
申请号:EP15784137.0
申请日:2015-10-19
发明人: GARALDE, Daniel Ryan , HERON, Andrew John , JAYASINGHE, Lakmal , TURNER, Daniel John , WHITE, James
IPC分类号: C12Q1/6869
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公开(公告)号:EP3440098A1
公开(公告)日:2019-02-13
申请号:EP17722128.0
申请日:2017-04-06
发明人: JAYASINGHE, Lakmal , BRUCE, Mark , MCNEILL, Luke , NATHANI, Ramiz Iqbal , SINGH, Pratik Raj , WOOD, Neil Roger , YOUNG, Stephen Robert
IPC分类号: C07K14/435 , C12Q1/68 , G01N27/447
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公开(公告)号:EP3423486A1
公开(公告)日:2019-01-09
申请号:EP17710372.8
申请日:2017-03-02
IPC分类号: C07K16/12 , C12Q1/68 , G01N33/483
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公开(公告)号:EP2310534B1
公开(公告)日:2018-09-05
申请号:EP09784654.7
申请日:2009-07-06
IPC分类号: C12Q1/68 , C07K14/245 , C12Q1/6869
CPC分类号: C07K14/245 , C12Q1/6869 , C12Q2565/631
摘要: The invention relates to a mutant α-hemolysin (α-HL) pore which is useful for detecting one or more nucleotides by stochastic sensing. The pore is particularly useful for sequencing DNA or RNA. A molecular adaptor that allows detection of the nucleotide(s) is covalently attached to the pore. The pore is specifically modified to facilitate positioning of the adaptor and may be modified to facilitate covalent attachment.
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公开(公告)号:EP3204511A1
公开(公告)日:2017-08-16
申请号:EP15784437.4
申请日:2015-10-06
发明人: JAYASINGHE, Lakmal , WALLACE, Elizabeth Jayne , PUGH, Jonathan Bankes , HAMBLEY, Richard George , WOOD, Neil Roger , HERON, Andrew John , WHITE, James
CPC分类号: C12Q1/6869 , B01L3/502761 , B01L2200/0663 , B01L2300/0636 , B01L2300/0896 , C07K14/35 , C12Q1/68 , G01N33/48721 , C12Q2565/607 , C12Q2565/631
摘要: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
摘要翻译: 本发明涉及Msp的突变形式。 本发明还涉及使用Msp进行多核苷酸表征。
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公开(公告)号:EP2875128B8
公开(公告)日:2020-06-24
申请号:EP13740348.1
申请日:2013-07-18
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公开(公告)号:EP2673638B1
公开(公告)日:2019-10-30
申请号:EP12703872.7
申请日:2012-02-10
IPC分类号: C07K14/35 , C12Q1/6869 , A61K39/00 , A61K39/04
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公开(公告)号:EP2875152B1
公开(公告)日:2019-10-09
申请号:EP13740351.5
申请日:2013-07-18
发明人: HERON, Andrew , CLARKE, James , MOYSEY, Ruth , WALLACE, Elizabeth Jayne , BRUCE, Mark , JAYASINGHE, Lakmal , CAPROTTI, Domenico , SOEROES, Szabolcs , MCNEILL, Luke , MISCA, Mihaela
IPC分类号: C12Q1/6869 , C12N9/14
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公开(公告)号:EP3423487A1
公开(公告)日:2019-01-09
申请号:EP17710373.6
申请日:2017-03-02
IPC分类号: C07K16/12 , C12Q1/68 , G01N33/483
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