公开(公告)号：EP1778103A4

公开(公告)日：2009-09-30

申请号：EP05792375

申请日：2005-08-30

申请人： PNEUMRX INC

发明人： MCGURK ERIN ,  MATHIS MARK ,  DIECK RONALD ,  WARTCHOW CHARLES

IPC分类号： A61B1/012

CPC分类号： A61B17/00491 ,  A61B17/0057 ,  A61B17/32002 ,  A61B17/34 ,  A61B17/3415 ,  A61B2017/00278 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/00641 ,  A61B2017/00809

公开(公告)号：EP1781182A4

公开(公告)日：2011-08-24

申请号：EP05770075

申请日：2005-07-08

申请人： PNEUMRX INC

发明人： MCGURK ERIN ,  DIECK RONALD ,  WARTCHOW CHARLES ,  GONG GLEN ,  BALCETA JOBERT

IPC分类号： A61B17/08 ,  A61K38/00

CPC分类号： A61B17/00491 ,  A61B2017/00495 ,  A61M25/0041 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/0074 ,  A61M31/00 ,  A61M2025/0073

摘要： The invention discloses a method of treating a patient for pleural effusion comprising percutaneously delivering an adhesive material to a pleural space of the patient. Suitable adhesive materials for performing any of the embodiments of the methods of the invention can be selected from the group consisting of hydrogels, collagen, poly(lactic acid), poly(glycolide), cyanoacrylates, glutaraldehyde, PEG, protein, and polysaccharide and derivatives thereof. The invention also discloses a pleural effusion treatment apparatus comprising an adhesive material adapted to adhere pleural membranes defining a pleural space and a pleural space access member adapted to deliver the adhesive material to the pleural space.

摘要翻译： 本发明公开了一种治疗患者胸腔积液的方法，包括将粘合剂材料经皮递送至患者的胸膜腔。 用于实施本发明方法的任何实施方案的合适的粘合剂材料可以选自水凝胶，胶原，聚（乳酸），聚（乙交酯），氰基丙烯酸酯，戊二醛，PEG，蛋白质和多糖及衍生物 它们。 本发明还公开了一种胸腔积液治疗装置，其包括适于粘附限定胸膜腔的胸膜的粘合剂材料和适于将粘合剂材料输送到胸膜腔的胸膜空间进入构件。

公开(公告)号：EP1773225A4

公开(公告)日：2010-05-26

申请号：EP05758569

申请日：2005-06-14

申请人： PNEUMRX INC

发明人： MCGURK ERIN ,  MATHIS MARK L ,  THOMPSON DAVE P ,  ARONSON NATHAN A

IPC分类号： A61B18/18 ,  A61B17/12 ,  A61B17/22 ,  A61F2/04 ,  A61M25/00 ,  A61M25/10 ,  A61M29/00

CPC分类号： A61M25/0026 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/12054 ,  A61B2017/12095 ,  A61B2017/22067 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0075 ,  A61M25/10 ,  A61M25/1027 ,  A61M2025/1052 ,  A61M2025/1054 ,  A61M2210/1039

摘要： The invention provides devices and systems for treating lungs. One aspect of the invention provides a lung device with an expandable member having an open lumen formed therethrough, the expandable (e.g., inflatable and compliant) member having an expanded diameter adapted to contact a circumferential wall portion of a lung air passageway. The device may also include a plug adapted to close the open lumen and a coupler adapted to couple the plug and the expandable member. Another aspect of the invention provides a lung device and delivery system including: an expandable member having an open lumen formed therethrough, the expandable member having an expanded diameter adapted to fit within a lung air passageway; and a delivery catheter adapted to deliver the expandable member to a lung air passageway, the delivery catheter having a coupler adapted to couple the catheter to the expandable member.

公开(公告)号：EP2432422A4

公开(公告)日：2018-01-17

申请号：EP10778273

申请日：2010-05-18

申请人： PNEUMRX INC

发明人： MATHIS MARK L ,  WU PATRICK ,  LEHRBERG DAVID ,  VASQUEZ JAIME ,  MCGURK ERIN ,  DIECK RONALD ,  STEIN ANDREW

IPC分类号： A61F2/04

CPC分类号： A61B17/12104 ,  A61B1/2676 ,  A61B17/10 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/1219 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61F2/04 ,  A61F2002/043

摘要： Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.