公开(公告)号：EP2432422A4

公开(公告)日：2018-01-17

申请号：EP10778273

申请日：2010-05-18

申请人： PNEUMRX INC

发明人： MATHIS MARK L ,  WU PATRICK ,  LEHRBERG DAVID ,  VASQUEZ JAIME ,  MCGURK ERIN ,  DIECK RONALD ,  STEIN ANDREW

IPC分类号： A61F2/04

CPC分类号： A61B17/12104 ,  A61B1/2676 ,  A61B17/10 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/1219 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61F2/04 ,  A61F2002/043

摘要： Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported.

公开(公告)号：EP2967822A4

公开(公告)日：2016-09-21

申请号：EP14770462

申请日：2014-03-13

申请人： PNEUMRX INC

发明人： VASQUEZ JAIME ,  MATHIS MARK L ,  MACHOLD TIMOTHY ,  STEIN ANDREW

IPC分类号： A61F2/04 ,  A61B1/267 ,  A61B17/00 ,  A61B17/12 ,  A61B90/00

CPC分类号： A61B17/12104 ,  A61B1/2676 ,  A61B17/12131 ,  A61B17/12145 ,  A61B17/1215 ,  A61B90/37 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61B2090/061 ,  A61B2090/0807 ,  A61B2090/373 ,  A61F2002/043 ,  A61F2250/0067 ,  A61F2250/0098

公开(公告)号：EP2341970A4

公开(公告)日：2015-04-08

申请号：EP09813753

申请日：2009-09-14

申请人： PNEUMRX INC

发明人： THOMPSON DAVID ,  WU PATRICK ,  LEHRBERG DAVID ,  MATHIS MARK L ,  BOUTILLETTE MICHAEL ,  ARONSON NATHAN ,  VASQUEZ JAIME

IPC分类号： A61M16/00 ,  A61B17/12

CPC分类号： A61B17/12104 ,  A61B5/087 ,  A61B5/091 ,  A61B5/14542 ,  A61B5/4848 ,  A61B6/032 ,  A61B17/12022 ,  A61B17/12131 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12172 ,  A61B17/1285 ,  A61B17/24 ,  A61B90/00 ,  A61B2017/00477 ,  A61B2017/00809 ,  A61B2017/12054 ,  A61B2090/061 ,  A61B2090/3966 ,  A61M16/04 ,  A61M16/0406 ,  A61M16/0833 ,  A61M2205/0266

摘要： A method of planning a lung volume reduction treatment for a lung of a patient, the lung including an airway system having a plurality of branching airways, the method comprising identifying a target axial region of the airway system, the target axial region having a proximal end toward the esophagus and a distal end away from the esophagus with a length therebetween; selecting an implant in response to the length of the target axial region such that the implant has an elongate body with a body length greater than the length of the target axial region; such that a distal end of the selected implant can be advanced through the airway system toward the distal end of the target axial region; and such that the implant can be deployed within the target axial region so that the elongate body laterally compresses a portion of the lung. A system for use in a lung volume reduction treatment plan resulting from the method, comprises a catheter having a proximal end and a distal end with a lumen therebetween, the distal end of the catheter being advanceable through the airway system; and an implant receivable by the lumen, the implant comprising an elongate body having a distal portion and a proximal portion adjacent a proximal end of the implant, and a body length greater than the length of the target axial region, the distal portion being biased so that retraction of the distal end of the catheter from the distal portion of the implant can release the distal portion to engage the airway, the proximal end of the implant being advanceable distally relative to the airway while the catheter is withdrawn proximally from the proximal portion of the implant.

公开(公告)号：EP1998713A4

公开(公告)日：2009-10-21

申请号：EP07752999

申请日：2007-03-13

申请人： PNEUMRX INC

发明人： THOMPSON DAVID ,  ARONSON NATHAN ,  WU PATRICK ,  LEHRBERG DAVID ,  MATHIS MARK ,  VASQUEZ JAIME

IPC分类号： A61F2/04

CPC分类号： A61M16/208 ,  A61B1/018 ,  A61B1/04 ,  A61B1/2676 ,  A61B5/06 ,  A61B6/032 ,  A61B6/12 ,  A61B6/485 ,  A61B17/00234 ,  A61B17/12022 ,  A61B17/12031 ,  A61B17/12104 ,  A61B17/12131 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B90/00 ,  A61B90/02 ,  A61B2017/00477 ,  A61B2017/00809 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61F2/04 ,  A61F2002/043 ,  A61F2002/046 ,  A61M16/04 ,  A61M16/0406 ,  A61M16/0833 ,  A61M37/0069 ,  A61M2205/0266 ,  A61M2205/32