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公开(公告)号：EP1525183A1
公开(公告)日：2005-04-27
申请号：EP03762206.5
申请日：2003-06-30
发明人： BATTISTINI, Carlo , CASUSCELLI, Francesco , KELLY, Robert, C. , MAGGIORA, Linda, L. , MITCHELL, Mark, A. , PIUTTI, Claudia , REDING, Matthew, T.
IPC分类号： C07C229/58 , C07C323/63 , C07D257/04 , A61P31/12
CPC分类号： C07D207/335 , C07C229/58 , C07C233/51 , C07C233/62 , C07C233/80 , C07C233/87 , C07C255/58 , C07C275/24 , C07C279/14 , C07C309/59 , C07C317/36 , C07C317/48 , C07C323/63 , C07C2601/02 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07D209/16 , C07D211/58 , C07D213/38 , C07D239/54 , C07D257/04 , C07D295/155 , C07D295/215 , C07D307/52 , C07D333/20 , C07D333/24
摘要： The present invention provides compounds of Formula I, compositions and methods that are useful for treating viral infections and associated diseases, particularly HCV infections and associated diseases.
摘要翻译： 本发明提供了用于治疗病毒感染和相关疾病，特别是HCV感染和相关疾病的式I化合物，组合物和方法。
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2.发明公开
公开(公告)号：EP1345909A1
公开(公告)日：2003-09-24
申请号：EP01983600.6
申请日：2001-11-22
发明人： PEVARELLO, Paolo , ORSINI, Paolo , TRAQUANDI, Gabriella , BRASCA, Maria, Gabriella , AMICI, Raffaella , VILLA, Manuela , PIUTTI, Claudia , VARASI, Mario , LONGO, Antonio
IPC分类号： C07D231/40 , C07D413/12 , C07D403/12 , C07D401/12 , A61K31/415 , A61P35/00
CPC分类号： C07D401/12 , C07D231/40 , C07D403/12 , C07D413/12
摘要： Phenylacetamido-pyrazoles of Formula (I) and, more particularly, N-(5-cycloalkyl-1H-pyrazol-3-yl) phenylacetamido derivatives, optionally further substituted as reported in the description; or pharmaceutically acceptable salts thereof; are useful in the treatment of cell proliferative disorders, e.g.cancer, associated with an altered cell cycle dependent kinase activity. Formula (I).
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3.发明公开CHROMANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS 审中-公开色，其制造方法相同，它们作为抗肿瘤药
公开(公告)号：EP1379524A2
公开(公告)日：2004-01-14
申请号：EP02719710.2
申请日：2002-01-17
发明人： TRAQUANDI, Gabriella , BRASCA, Maria, Gabriella , ORSINI, Paolo , PIUTTI, Claudia , VULPETTI, Anna , PEVARELLO, Paolo
IPC分类号： C07D405/12 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , A61K31/4155 , A61P35/00
CPC分类号： C07D401/12 , A61K31/415 , A61K31/47 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14
摘要： Compounds which are chromane derivatives of formula (I), pharmaceutically acceptable salts, process for their preparation and pharmaceutical compositions thereof are disclosed, as set forth in the specification; these compounds are useful in therapy in the treatment of cell proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.
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