公开(公告)号：EP3028033B1

公开(公告)日：2020-10-07

申请号：EP14835171.1

申请日：2014-06-10

Applicant: Photonicsys Ltd.

Inventor： ABDULHALIM, Ibrahim

IPC: G01N21/552 ,  G01N29/02 ,  G01N29/24 ,  G01N21/64 ,  G01N21/65 ,  B82Y30/00

公开(公告)号：EP3028033A1

公开(公告)日：2016-06-08

申请号：EP14835171.1

申请日：2014-06-10

Applicant: Photonicsys Ltd.

Inventor： ABDULHALIM, Ibrahim

IPC: G01N21/552 ,  G01N21/41 ,  G01N33/483 ,  B82Y15/00 ,  B82Y30/00 ,  G01N29/02

CPC classification number: G01N21/554 ,  B82Y20/00 ,  B82Y30/00 ,  G01N21/648 ,  G01N21/658 ,  G01N21/7703 ,  G01N29/022 ,  G01N29/2418 ,  G01N2021/7709 ,  G01N2021/7776 ,  G01N2201/06113 ,  G01N2201/0612 ,  G01N2201/0633 ,  G01N2201/068 ,  Y10S977/954

Abstract: The invention is a SPR sensor that comprises a multi-layered plasmonic structure on a substrate for sensing. The SPR sensor has an enhanced figure of merit and lower limit of detection (system noise divided by the sensitivity) by at least two orders of magnitude than prior art SPR sensors. The plasmonic structure of the invention comprises a Nanostructured Porous Metal Layer (NPML) and at least one of: (a) buried dielectric layer under the nano-porous metal layer; (b) a nano-dimensional high index layer on top of the metal layer; and (c) a molecular layer for bio-functionalization adjacent to an analyte layer. The invention also encompasses many embodiments of measuring systems that comprise the SPR sensors of the invention with improved signal to noise ratio.

Abstract translation: 本发明是一种SPR传感器，其包括用于感测的衬底上的多层等离子体激元结构。 SPR传感器具有增强的品质因数和检测下限（系统噪声除以灵敏度）比现有技术SPR传感器至少两个数量级。 本发明的等离子体激元结构包括纳米结构的多孔金属层（NPML）和以下至少一种：（a）在纳米多孔金属层下方的埋置介电层; （b）金属层顶部的纳米尺寸高折射率层; 和（c）与分析物层相邻的用于生物官能化的分子层。 本发明还包括测量系统的许多实施例，其包括具有改善的信噪比的本发明的SPR传感器。