公开(公告)号：EP2201052A1

公开(公告)日：2010-06-30

申请号：EP08845161.2

申请日：2008-10-08

申请人： Polyintell

发明人： PEROLLIER, Céline ,  BAYOUDH, Sami

IPC分类号： C08F220/38 ,  G01N33/531

CPC分类号： G01N33/68 ,  C08F220/38 ,  G01N2600/00

摘要： The present invention relates to new molecularly imprinted polymers which are suitable for the selective recognition of glutathione GSH and/or of an analogue thereof, and in particular which are of use for the treatment of media comprising in particular a mixture of glutathione GSH, and/or of an analogue thereof, with GSH adducts.

公开(公告)号：EP2201052B1

公开(公告)日：2012-12-12

申请号：EP08845161.2

申请日：2008-10-08

申请人： Polyintell

发明人： PEROLLIER, Céline ,  BAYOUDH, Sami

IPC分类号： C08F246/00 ,  G01N33/68 ,  B01J20/26 ,  C08F220/28 ,  C08F226/06 ,  C08F222/10

CPC分类号： G01N33/68 ,  C08F220/38 ,  G01N2600/00

公开(公告)号：EP2544993A1

公开(公告)日：2013-01-16

申请号：EP11713069.0

申请日：2011-03-07

申请人： Polyintell

发明人： PEROLLIER, Céline ,  NARAGHI, Kaynoush ,  BAYOUDH, Sami

IPC分类号： C01B9/08 ,  C07B59/00 ,  C07D207/12

CPC分类号： C01B9/08 ,  C01B7/20 ,  C07B59/00 ,  C07D207/16 ,  C07D401/06 ,  C07D401/14

摘要： The present invention relates to a method for preparing a radioactive tracer provided with a radioactive fluorine isotope, including at least the following steps consisting in: i) providing a precursor of the radioactive tracer, comprising at least one leaving group completely or partially formed by a labelling entity, wherein said leaving group can be moved by a fluoride ion; ii) providing a molecularly imprinted polymer dedicated to the molecular recognition of at least the aforementioned labelling entity; iii) exposing the precursor to a radioactive fluoride ion source under conditions suitable for the movement of the leaving group by a radioactive fluoride ion; iv) placing the mixture resulting from step (iii) in contact with the molecularly imprinted polymer under conditions suitable for the recognition of the labelling entity; and v) obtaining a solution containing the radioactive tracer provided with a radioactive isotope of fluorine obtained at the end of step (iii).

公开(公告)号：EP2324357A1

公开(公告)日：2011-05-25

申请号：EP09787149.5

申请日：2009-09-09

申请人： Polyintell

发明人： LE FOLL, Alexandra ,  LEVACHER, Vincent ,  PEROLLIER, Céline ,  BAYOUDH, Sami ,  NARAGHI, Kaynoush

IPC分类号： G01N33/531

CPC分类号： G01N33/531 ,  B01J20/268 ,  B01J20/285 ,  C07D249/04 ,  C08F220/06 ,  C08F222/1006 ,  G01N33/542 ,  G01N2030/027 ,  G01N2600/00

摘要： The present invention relates to a kit useful for separating and/or characterizing at least one molecule A of interest, said kit comprising at least: (i) a compound of the following general formula (I): B-(R)
n -Z (I) in which: B represents a hydrogen atom or a detectable labelling entity; R represents a C
1 -C
10000 hydrocarbon unit which may be alternatively polymeric or non-polymeric and optionally incorporate one or more heteroatoms, chosen from N, O, S, Br, Cl, F, P, B, Si and/or one or more metals; n represents 0 or 1, with n being equal to 1, when B represents a hydrogen atom; and Z represents a functional group capable of reacting in a click chemistry reaction in order to form a linking function L
click; and (ii) a molecularly imprinted polymer dedicated to the molecular recognition of at least said linking function L
click .

公开(公告)号：EP2125195A2

公开(公告)日：2009-12-02

申请号：EP08775729.0

申请日：2008-03-20

申请人： Polyintell

发明人： PEROLLIER, Céline ,  NARAGHI, Kaynoush ,  BAYOUDH, Sami

IPC分类号： B01J20/26 ,  G01N33/52 ,  G01N33/53 ,  G01N33/58 ,  B01D15/08 ,  B01D15/38

CPC分类号： G01N33/531 ,  B01J20/26 ,  B01J20/268 ,  B01J20/285 ,  B01J2220/54 ,  G01N30/02 ,  G01N33/9413 ,  G01N2600/00 ,  Y10T436/144444 ,  Y10T436/145555 ,  Y10T436/173845 ,  B01D15/3852

摘要： The present invention relates to a kit for analysing at least one target molecule comprising at least a first molecularly imprinted polymer and a second molecularly imprinted polymer which are chemically identical or different, capable of interacting with the target molecule(s), and at least one marker, wherein said marker is either a competitive marker or marker capable (i) of interacting with all or part of the recognition sites for the target molecule(s) of the second molecularly imprinted polymer and (ii) of being displaced from said recognition site(s) by the target molecule(s) when said second molecularly imprinted polymer is placed in the presence of said target molecule(s), or an intrinsic marker or a constitutive unit of the second molecularly imprinted polymer, capable (i') of interacting with all or part of the target molecule(s) when the latter interact(s) with all or part of its recognition sites for said target molecule(s) and (ii') of consequently emitting a detectable signal.