公开(公告)号：EP2687278B1

公开(公告)日：2018-05-30

申请号：EP13176179.3

申请日：2013-07-11

申请人： Kabushiki Kaisha Toshiba

发明人： WATANDO, Hiroko ,  KUBOKI, Takashi

IPC分类号： B01D15/00 ,  B01J39/02 ,  B01D53/14 ,  B01J20/04 ,  B01J39/17 ,  B01J49/06 ,  B01J49/53 ,  B01J49/60

CPC分类号： G01N30/96 ,  B01D15/00 ,  B01D53/1418 ,  B01D53/1475 ,  B01J39/17 ,  B01J49/06 ,  B01J49/53 ,  B01J49/60 ,  C07C213/10 ,  C07C241/00 ,  Y02C10/06 ,  Y02C10/08 ,  Y10T436/147777 ,  Y10T436/170769 ,  Y10T436/173845

摘要： The objects of embodiments in the present disclosure are to provide a method capable of recovering two or more amine compounds at the same time from a gas or solution, and also to provide a method capable of analyzing the recovered amines. The amine-recovering method comprises the steps (A) and (B). In the step (A), the gas or solution is brought into contact with a solid adsorbent so that the adsorbent may retain the amines. In the step (B), the amines retained by the adsorbent in the step (A) are eluted out by use of a basic compound-containing organic solvent. The solid adsorbent has a substituent group represented by -SO 3 M (M is H or an alkali metal).

公开(公告)号：EP2021761B1

公开(公告)日：2017-11-29

申请号：EP07748115.8

申请日：2007-05-08

申请人： Provtagaren Ab

发明人： SKARPING, Gunnar ,  DALENE, Marianne

IPC分类号： G01N1/22 ,  G01N21/78

CPC分类号： G01N1/2214 ,  G01N21/783 ,  G01N31/22 ,  Y10T436/17 ,  Y10T436/172307 ,  Y10T436/173845 ,  Y10T436/20 ,  Y10T436/21

摘要： A sampling device for analysis of a substance which is chosen from the group consisting of isocyanates, aminoisocyanates, amines, and isothiocyanates, and which is present in an air flow intended to pass through the sampling device is disclosed, as well as a method for the production of said sampling device, and a method for the analysis of said substance in the air flow.

公开(公告)号：EP2627817B1

公开(公告)日：2016-07-06

申请号：EP11761764.7

申请日：2011-09-16

申请人： Illinois Tool Works Inc.

发明人： JELONEK, Paul, Richard ,  BERNARDO, Ernani

IPC分类号： D06P1/00 ,  D06P1/651 ,  A47L13/17 ,  C09D11/00 ,  C11D3/00 ,  C11D17/04 ,  D06P1/52 ,  G01N31/22 ,  C09D11/10 ,  C09D11/50

CPC分类号： C09D11/50 ,  A47L13/17 ,  C11D3/40 ,  C11D17/049 ,  D06P1/00 ,  D06P1/525 ,  D06P1/5264 ,  D06P1/5278 ,  D06P1/5285 ,  D06P1/65168 ,  D06P1/65193 ,  G01N31/22 ,  Y10T436/173845 ,  Y10T442/20 ,  Y10T442/2525

公开(公告)号：EP2818870A4

公开(公告)日：2016-02-10

申请号：EP13752246

申请日：2013-02-22

申请人： UNIV KEIO ,  YAKULT HONSHA KK

发明人： TANIGAWARA YUSUKE ,  NISHIMUTA AKITO ,  TSUZAKI JUNYA ,  TAKAHASHI HIROYUKI

IPC分类号： A61K31/513 ,  A61K31/555 ,  A61K45/00 ,  A61K45/06 ,  A61K47/18 ,  A61K47/26 ,  A61P43/00 ,  G01N33/15 ,  G01N33/50 ,  G01N33/574

CPC分类号： G01N33/57484 ,  A61K31/282 ,  A61K31/513 ,  A61K31/555 ,  A61K45/06 ,  A61K47/18 ,  A61K47/183 ,  A61K47/26 ,  G01N33/574 ,  G01N33/6848 ,  G01N2560/00 ,  G01N2570/00 ,  G01N2800/52 ,  Y10T436/143333 ,  Y10T436/147777 ,  Y10T436/163333 ,  Y10T436/173845 ,  Y10T436/201666 ,  A61K2300/00

摘要： To provide an anti-cancer agent sensitivity determination marker, which marker can determine whether or not the patient has a therapeutic response to the anti-cancer agent, and novel cancer therapeutic means employing the marker. The anti-cancer agent sensitivity determination marker, the anti-cancer agent including oxaliplatin or a salt thereof and fluorouracil or a salt thereof, contains one or more substances selected from among an amino-acid-metabolism-related substance, a nucleic-acid-metabolism-related substance, a substance in the pentose phosphate pathway, a substance in the glycolytic pathway, a substance in the TCA cycle, a polyamine-metabolism-related substance, 7,8-dihydrobiopterin, 6-phosphogluconic acid, butyric acid, triethanolamine, 1-methylnicotinamide, NADH, NAD + , and a substance involved in the metabolism of any of these substances.

公开(公告)号：EP2836833A4

公开(公告)日：2015-10-14

申请号：EP13775727

申请日：2013-04-12

申请人： UNIV WAYNE STATE ,  NICOLAIDES KYPROS

发明人： NICOLAIDES KYPROS ,  BAHADO-SINGH RAY

IPC分类号： G01N33/68 ,  G06F19/00

CPC分类号： G01N33/70 ,  G01N33/492 ,  G01N33/50 ,  G01N33/6806 ,  G01N33/6812 ,  G01N2570/00 ,  G01N2800/387 ,  G16H50/30 ,  Y10T436/147777 ,  Y10T436/173845 ,  Y10T436/201666 ,  Y10T436/203332

摘要： The present invention is directed to methods for predicting a pregnant woman's risk of carrying a fetus with Down syndrome (Trisomy 21) or Trisomy 18. The methods are based on measuring one or more metabolites obtained from a pregnant woman's bodily fluid, such as blood or urine, and found to be predictive of Trisomy 21 or Trisomy 18.

摘要翻译： 本发明涉及用于预测怀孕妇女携带唐氏综合症（三体积21）或三体层析器18的胎儿的风险的方法。该方法基于测量从孕妇身体液体获得的一种或多种代谢物，例如血液或 尿，并发现可预测三体21或三体18。

公开(公告)号：EP2756095A4

公开(公告)日：2015-07-22

申请号：EP12831223

申请日：2012-09-11

申请人： METABOLON INC

发明人： GALL WALTER ,  LAWTON KAY A

IPC分类号： G01N33/50 ,  A61K31/661 ,  A61K31/685 ,  G01N33/68 ,  G01N33/92

CPC分类号： G01N33/92 ,  A61K31/661 ,  A61K31/685 ,  G01N33/5023 ,  G01N33/507 ,  G01N33/6893 ,  G01N2500/04 ,  G01N2500/10 ,  G01N2800/042 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/56 ,  Y10T436/143333 ,  Y10T436/173845 ,  Y10T436/174614 ,  Y10T436/201666

公开(公告)号：EP2652494B1

公开(公告)日：2015-01-07

申请号：EP11817341.8

申请日：2011-12-14

申请人： Commissariat à l'Énergie Atomique et aux Énergies Alternatives ,  Centre National de la Recherche Scientifique (CNRS)

发明人： TRAN-THI, Thu-Hoa ,  GARCIA, Julien ,  NGUYEN, Thi Dinh ,  NGUYEN, Trung-Hieu

IPC分类号： G01N31/22 ,  G01N21/77

CPC分类号： G01N21/783 ,  G01N31/224 ,  Y10T436/173845 ,  Y10T436/177692 ,  Y10T436/19

公开(公告)号：EP2818870A1

公开(公告)日：2014-12-31

申请号：EP13752246.2

申请日：2013-02-22

申请人： Keio University ,  Kabushiki Kaisha Yakult Honsha

发明人： TANIGAWARA, Yusuke ,  NISHIMUTA, Akito ,  TSUZAKI, Junya ,  TAKAHASHI, Hiroyuki

IPC分类号： G01N33/68 ,  A61K31/282 ,  A61K31/513 ,  A61K45/00 ,  A61P35/00 ,  A61P43/00 ,  G01N33/15 ,  G01N33/50

CPC分类号： G01N33/57484 ,  A61K31/282 ,  A61K31/513 ,  A61K31/555 ,  A61K45/06 ,  A61K47/18 ,  A61K47/183 ,  A61K47/26 ,  G01N33/574 ,  G01N33/6848 ,  G01N2560/00 ,  G01N2570/00 ,  G01N2800/52 ,  Y10T436/143333 ,  Y10T436/147777 ,  Y10T436/163333 ,  Y10T436/173845 ,  Y10T436/201666 ,  A61K2300/00

摘要： To provide an anti-cancer agent sensitivity determination marker, which marker can determine whether or not the patient has a therapeutic response to the anti-cancer agent, and novel cancer therapeutic means employing the marker.
The anti-cancer agent sensitivity determination marker, the anti-cancer agent including oxaliplatin or a salt thereof and fluorouracil or a salt thereof, contains one or more substances selected from among an amino-acid-metabolism-related substance, a nucleic-acid-metabolism-related substance, a substance in the pentose phosphate pathway, a substance in the glycolytic pathway, a substance in the TCA cycle, a polyamine-metabolism-related substance, 7,8-dihydrobiopterin, 6-phosphogluconic acid, butyric acid, triethanolamine, 1-methylnicotinamide, NADH, NAD + , and a substance involved in the metabolism of any of these substances.

摘要翻译： 为了提供抗癌剂灵敏度测定标记，该标记可以确定患者是否具有对抗癌剂的治疗应答，以及采用该标记的新型癌症治疗方法。 抗癌剂敏感性测定标记物，包括奥沙利铂或其盐的抗癌剂和氟尿嘧啶或其盐含有选自氨基酸 - 代谢相关物质，核酸 - 代谢相关物质，戊糖磷酸途径中的物质，糖酵解途径中的物质，TCA循环中的物质，多胺代谢相关物质，7,8-二氢生物蝶呤，6-磷酸葡萄糖酸，丁酸，三乙醇胺 ，1-甲基烟酰胺，NADH，NAD +和涉及任何这些物质代谢的物质。

公开(公告)号：EP2756304A1

公开(公告)日：2014-07-23

申请号：EP12831825.0

申请日：2012-09-14

申请人： BASF SE

发明人： KAMP, Hennicke ,  WALK, Tilmann B. ,  RAVENZWAAY, Bennard van ,  MELLERT, Werner ,  FABIAN, Eric ,  STRAUSS, Volker ,  WIEMER, Jan C. ,  LOOSER, Ralf ,  HEROLD, Michael, Manfred ,  PROKOUDINE, Alexandre

IPC分类号： G01N33/53

CPC分类号： G01N33/5014 ,  G01N33/62 ,  G01N33/6893 ,  G01N33/70 ,  G01N33/92 ,  G01N2500/04 ,  G01N2800/347 ,  Y10T436/171538 ,  Y10T436/173845 ,  Y10T436/24

摘要： The present invention pertains to the field of diagnostics for kidney toxicity and toxicological assessments for risk stratification of chemical compounds. Specifically, it discloses a method for diagnosing kidney toxicity. It also discloses a method for determining whether a compound is capable of inducing such kidney toxicity in a subject and a method of identifying a drug for treating kidney toxicity. Furthermore, the present invention discloses a device and a kit for diagnosing kidney toxicity.

公开(公告)号：EP1985670B1

公开(公告)日：2014-01-08

申请号：EP07707001.9

申请日：2007-01-18

申请人： ARKRAY, Inc.

发明人： YONEHARA, Satoshi ,  INAMURA, Norio

IPC分类号： C09B67/26 ,  C09B21/00 ,  G01N31/22 ,  C09B69/04

CPC分类号： C09B69/04 ,  C09B67/0076 ,  G01N31/22 ,  Y10T436/10 ,  Y10T436/17 ,  Y10T436/173845 ,  Y10T436/25 ,  Y10T436/2525