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公开(公告)号：EP3442991A1
公开(公告)日：2019-02-20
申请号：EP17783273.0
申请日：2017-04-14
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公开(公告)号：EP4223317A3
公开(公告)日：2023-09-27
申请号：EP23165319.7
申请日：2015-06-12
发明人： Hoarty, Michelle Denise , Dhamnaskar, Ketki Ashok , Elbaum, Daniel , Josephson, Kristopher , Larson, Kelley Cronin , MA, Zhong , Nims, Nathan Ezekiel , Ricardo, Alonso , Seyb, Kathleen , Tang, Guo-Qing , Treco, Douglas A. , Wang, Zhaolin , YE, Ping , Zheng, Hong , Perlmutter, Sarah Jacqueline , Hammer, Robert
IPC分类号： C07K7/64 , A61K47/64 , A61P7/00 , A61P9/00 , A61P13/00 , A61P17/02 , A61P25/00 , A61P27/02 , A61P29/00 , A61P37/06 , A61K38/00
摘要： The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.
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公开(公告)号：EP2850095A1
公开(公告)日：2015-03-25
申请号：EP13790527.9
申请日：2013-03-14
发明人： WANG, Zhaolin , YE, Ping , RICARDO, Alonso , JOSEPHSON, Kristopher , ANDERSON, Paul , ARATA, Michelle, Denise , MA, Zhong , NIMS, Nathan, Ezekiel , SCHNEIDER, Eberhard , SCHURMANN, Gregor , WAGNER, Peter , TRECO, Douglas, A. , ZHENG, Hong , ELBAUM, Daniel , BOYER, Nicolas, Cedric
IPC分类号： C07K7/54
CPC分类号： A61K38/10 , A61K9/0048 , A61K9/0051 , A61K38/00 , A61K45/06 , A61K47/60 , C07K7/08 , C08G65/48
摘要： The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.
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公开(公告)号：EP4223317A2
公开(公告)日：2023-08-09
申请号：EP23165319.7
申请日：2015-06-12
发明人： Hoarty, Michelle Denise , Dhamnaskar, Ketki Ashok , Elbaum, Daniel , Josephson, Kristopher , Larson, Kelley Cronin , MA, Zhong , Nims, Nathan Ezekiel , Ricardo, Alonso , Seyb, Kathleen , Tang, Guo-Qing , Treco, Douglas A. , Wang, Zhaolin , YE, Ping , Zheng, Hong , Perlmutter, Sarah Jacqueline , Hammer, Robert
摘要： The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.
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公开(公告)号：EP3973994A1
公开(公告)日：2022-03-30
申请号：EP21192106.9
申请日：2015-06-12
发明人： Hoarty, Michelle Denise , Dhamnaskar, Ketki Ashok , Elbaum, Daniel , Josephson, Kristopher , Larson, Kelley Cronin , MA, Zhong , Nims, Nathan Ezekiel , Ricardo, Alonso , Seyb, Kathleen , Tang, Guo-Qing , Treco, Douglas A. , Wang, Zhaolin , YE, Ping , Zheng, Hong , Perlmutter, Sarah Jacqueline , Hammer, Robert
摘要： The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.
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公开(公告)号：EP3154561A2
公开(公告)日：2017-04-19
申请号：EP15807069.8
申请日：2015-06-12
发明人： ARATA, Michelle Denise , DHAMNASKAR, Ketki Ashok , ELBAUM, Daniel , JOSEPHSON, Kristopher , LARSON, Kelley Cronin , MA, Zhong , NIMS, Nathan Ezekiel , RICARDO, Alonso , SEYB, Kathleen , TANG, Guo-Qing , TRECO, Douglas A. , WANG, Zhaolin , YE, Ping , ZHENG, Hong , PERLMUTTER, Sarah Jacqueline
摘要： The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.
摘要翻译： 本发明提供补体活性的调节剂。 还提供了利用这种调节剂作为治疗剂的方法。
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公开(公告)号：EP2850095B1
公开(公告)日：2019-10-09
申请号：EP13790527.9
申请日：2013-03-14
发明人： WANG, Zhaolin , YE, Ping , RICARDO, Alonso , JOSEPHSON, Kristopher , ANDERSON, Paul , ARATA, Michelle, Denise , MA, Zhong , NIMS, Nathan, Ezekiel , SCHNEIDER, Eberhard , SCHURMANN, Gregor , WAGNER, Peter , TRECO, Douglas, A. , ZHENG, Hong , ELBAUM, Daniel , BOYER, Nicolas, Cedric
IPC分类号： C07K7/54
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公开(公告)号：EP3154561B1
公开(公告)日：2019-09-04
申请号：EP15807069.8
申请日：2015-06-12
发明人： HOARTY, Michelle Denise , DHAMNASKAR, Ketki Ashok , ELBAUM, Daniel , JOSEPHSON, Kristopher , LARSON, Kelley Cronin , MA, Zhong , NIMS, Nathan Ezekiel , RICARDO, Alonso , SEYB, Kathleen , TANG, Guo-Qing , TRECO, Douglas A. , WANG, Zhaolin , YE, Ping , ZHENG, Hong , PERLMUTTER, Sarah Jacqueline , HAMMER, Robert Paul
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公开(公告)号：EP3250230A1
公开(公告)日：2017-12-06
申请号：EP16744125.2
申请日：2016-01-28
发明人： HOARTY, Michelle, Denise , DHAMNASKAR, Ketki, Ashok , ELBAUM, Daniel , JOSEPHSON, Kristopher , LARSON, Kelley, Cronin , MA, Zhong , NIMS, Nathan, Ezekiel , RICARDO, Alonso , SEYB, Kathleen , TANG, Guo-Qing , TRECO, Douglas, A. , WANG, Zhaolin , YE, Ping , ZHENG, Hong , PERLMUTTER, Sarah, Jacqueline
IPC分类号： A61K39/00 , A61K39/395
CPC分类号： A61K38/10 , A61K39/00 , C07K16/36 , C07K2317/76
摘要： The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.
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