公开(公告)号：EP1578733A1

公开(公告)日：2005-09-28

申请号：EP02781613.1

申请日：2002-12-10

申请人： RANBAXY LABORATORIES, LTD.

发明人： KUMAR, Yatendra ,  MEERAN, Hashim N.P.N.,Uzhijethu House ,  DE, Shantanu ,  RAFEEQ, Mohammad ,  SATHYANARAYANA, Swargam

IPC分类号： C07D239/42 ,  C07F9/535 ,  C07F7/18

CPC分类号： C07D239/42 ,  C07F7/1856 ,  C07F9/5352

摘要： The present invention relates to a process for the preparation of rosuvastatin calcium, a promising new HMG-CoA reductase inhibitor.

公开(公告)号：EP1383741A2

公开(公告)日：2004-01-28

申请号：EP02703802.5

申请日：2002-03-14

申请人： RANBAXY LABORATORIES, LTD.

发明人： THAPER, Rajesh Kumar ,  KUMAR, Yatendra ,  DE, Shantanu ,  KUMAR, Dileep S. M.

IPC分类号： C07C303/00 ,  C07C307/00 ,  C07C309/00 ,  C07C311/00 ,  C07D223/04 ,  C07D487/00 ,  C07D491/00 ,  C07D498/00 ,  C07D513/00

CPC分类号： C07C303/28 ,  C07D223/16 ,  C07C309/65

摘要： The present invention relates to an improved process for the preparation of trifluoromethanesulfonic ester of ethyl (R)-2-hydroxy-4-phenylbutyrate, referred to here as triflate in structural Formula I, and to the use of this compound as intermediate for the preparation of ACE (Angiotensin Converting Enzyme) inhibitor, benazepril.

公开(公告)号：EP1585736A2

公开(公告)日：2005-10-19

申请号：EP03725478.6

申请日：2003-05-21

申请人： RANBAXY LABORATORIES, LTD.

发明人： KUMAR, Yatendra ,  DE, Shantanu ,  RAFEEQ, Mohammad ,  MEERAN, Hashim Nizar Poovanathil Nagoor ,  SATHYANARAYANA, Swargam

IPC分类号： C07D239/00

CPC分类号： C07D239/42

摘要： The present invention relates to a cost effective and industrially advantageous process for the preparation of 4-4(fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)-5-pyrimidinecarboxaldehyde, referred to here as pyrimidine aldehyde of structural Formula I and to the use of this compound as intermediate for the preparation of rosuvastatin.

摘要翻译： 本发明涉及用于制备4-（氟苯基）-6-异丙基-2-（N-甲基-N-甲基磺酰基氨基）-5-嘧啶甲醛的成本有效且工业上有利的方法，该方法在此被称为嘧啶醛 结构式I以及该化合物作为制备瑞舒伐他汀的中间体的用途。