专利检索 ap:("REVIVICOR INC") AND inv:"AYARES DAVID" 第 1 页

1.

发明公开
MULTI-TRANSGENIC PIGS FOR DIABETES TREATMENT 审中-公开
标题翻译：多转基因猪治疗糖尿病

公开(公告)号：EP2464219A4

公开(公告)日：2013-08-21

申请号：EP10808879

申请日：2010-08-16

申请人： REVIVICOR INC

发明人： AYARES DAVID

IPC分类号： A01K67/00 , A61K35/39 , C12N15/00 , C12N15/85

CPC分类号： A01K67/0276 , A01K67/0278 , A01K2217/052 , A01K2217/075 , A01K2217/15 , A01K2217/206 , A01K2227/105 , A01K2227/108 , A01K2267/025 , A01K2267/0362 , A61K35/39 , C12N9/1051 , C12N15/8509 , C12N2830/40 , C12Y204/01087

摘要： The present invention provides certain animals, and in particular porcine animals, tissue and cells derived from these, which lack any expression of functional alpha 1,3 galactosyltransferase (αGT) and express one or more additional transgenes which make them suitable donors for pancreatic islet xenotransplantation. Methods of treatment and prevention of diabetes using cells derived from such animals are also provided.

2.

发明公开
UNGULATES WITH GENETICALLY MODIFIED IMMUNE SYSTEMS 审中-公开
标题翻译：蹄动物基因改造的免疫系统

公开(公告)号：EP1811832A4

公开(公告)日：2009-12-30

申请号：EP05818708

申请日：2005-10-24

申请人： REVIVICOR INC

发明人： WELLS KEVIN , AYARES DAVID

IPC分类号： C12N15/85 , A01K67/027 , C07K16/00 , C12N5/10 , C12N15/00

CPC分类号： A01K67/0276 , A01K2207/15 , A01K2217/00 , A01K2217/075 , A01K2227/101 , A01K2227/102 , A01K2227/103 , A01K2227/108 , A01K2267/01 , A01K2267/02 , A01K2267/025 , C12N15/8509 , C12N15/873 , C12N2800/204 , C12N2800/206 , C12N2800/30

3.

发明公开
TISSUE PRODUCTS DERIVED FROM ANIMALS LACKING ANY EXPRESSION OF FUNCTIONAL ALPHA 1,3 GALACTOSYLTRANSFERASE 有权
标题翻译：薄页纸产品动物没有任何表情的官能的α-半乳糖基转移1,3

公开(公告)号：EP1734814A4

公开(公告)日：2009-08-26

申请号：EP05732639

申请日：2005-03-17

申请人： REVIVICOR INC

发明人： AYARES DAVID , ROHRICHT PAUL

IPC分类号： A01K67/00 , A61F2/02 , A61F2/08 , A61F2/10 , A61F2/28 , A61K48/00 , A61L27/36 , C12N9/10 , C12N15/85

CPC分类号： A61L27/3683 , A01K67/0276 , A01K2217/075 , A01K2227/108 , A01K2267/02 , A01K2267/025 , A61K35/12 , A61L27/3604 , A61L27/3629 , A61L27/3641 , A61L27/3695 , A61L2430/34 , C12N9/1051 , C12N15/8509

摘要： The present invention provides tissues derived from animals, which lack any expression of functional alpha 1,3 galactosyltransferase (alpha-1,3-GT). Such tissues can be used in the field of xenotransplantation, such as orthopedic reconstruction and repair, skin repair and internal tissue repair or as medical devices.