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1.发明公开ARYL AND HETEROARYL QUINAZOLINE COMPOUNDS WHICH INHIBIT CSF-1R RECEPTOR TYROSINE KINASE 失效ARYL和HETEROARYL中氮唑类化合物阻止CSF-1R受体的酪氨酸激酶
公开(公告)号：EP0871448A4
公开(公告)日：1999-12-29
申请号：EP95904308
申请日：1994-12-08
发明人： MYERS MICHAEL R , SPADA ALFRED P , MAGUIRE MARTIN P , PERSONS PAUL E , ZILBERSTEIN ASHER , HSU CHIN-YI JENNY , JOHNSON SUSAN E
IPC分类号： A61K31/495 , A61K31/517 , A61K31/5377 , A61P19/00 , A61P35/00 , A61P37/00 , A61P39/00 , C07C43/205 , C07C43/225 , C07C43/23 , C07D213/30 , C07D213/64 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/22 , C07D215/233 , C07D215/50 , C07D239/74 , C07D239/88 , C07D239/91 , C07D239/93 , C07D239/94 , C07D241/42 , C07D241/52 , C07D265/22 , C07D277/64 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D471/04 , A61K31/505 , A61K31/535 , C07D239/72 , C07D241/04 , C07D265/28 , C07D319/18 , C07D333/06
CPC分类号： C07D213/30 , A61K31/517 , A61K31/5377 , C07C43/2055 , C07C43/225 , C07C43/23 , C07D213/64 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/233 , C07D215/50 , C07D239/74 , C07D239/88 , C07D239/91 , C07D239/93 , C07D239/94 , C07D241/42 , C07D241/52 , C07D265/22 , C07D277/64 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D471/04
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2.发明公开PYRAZOLO 3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE 失效吡唑并（3,4-G）喹喔啉ALS PDGF受体蛋白酪氨酸激酶抑制剂
公开(公告)号：EP0779889A4
公开(公告)日：2000-02-23
申请号：EP95932446
申请日：1995-09-06
发明人： MYERS MICHAEL R , PERSONS PAUL E , LY CUONG Q , SPADA ALFRED P
IPC分类号： A61K31/495 , A61P9/10 , A61P13/02 , A61P15/00 , A61P29/00 , A61P35/00 , A61P35/02 , C07D487/04
CPC分类号： C07D487/04
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3.发明公开PROTEIN TYROSINE KINASE ARYL AND HETEROARYL QUINAZOLINE COMPOUNDS HAVING SELECTIVE INHIBITION OF HER-2 AUTOPHOSPHORYLATION PROPERTIES 失效芳基和HETEROARYLCHINZOLINVERBINDUNGEN与蛋白质酪氨酸激酶PROPERTIES HAVING HER-2 AUTOPHOSPHORYLIERUNGSEIGENSCHAFTEN自己的一个选择性抑制
公开(公告)号：EP0831831A4
公开(公告)日：1998-05-27
申请号：EP96918362
申请日：1996-06-06
IPC分类号： C07D239/42 , A61K31/495 , A61K31/505 , A61K31/517 , A61K31/5377 , A61P9/10 , A61P29/00 , A61P31/12 , A61P35/00 , A61P43/00 , C07C43/205 , C07C43/225 , C07C43/23 , C07D213/30 , C07D213/64 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/22 , C07D215/233 , C07D215/50 , C07D239/74 , C07D239/88 , C07D239/91 , C07D239/93 , C07D239/94 , C07D241/42 , C07D241/52 , C07D265/22 , C07D277/64 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D471/04 , A61K31/535 , A61K31/50
CPC分类号： C07C43/2055 , A61K31/517 , A61K31/5377 , C07C43/225 , C07C43/23 , C07D213/30 , C07D213/64 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/233 , C07D215/50 , C07D239/74 , C07D239/88 , C07D239/91 , C07D239/93 , C07D239/94 , C07D241/42 , C07D241/52 , C07D265/22 , C07D277/64 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D471/04
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4.发明公开QUINOLINE AND QUINOXALINE COMPOUNDS WHICH INHIBIT PLATELET-DERIVED GROWTH FACTOR AND/OR P56?lck TYROSINE KINASES 失效喹啉和喹喔啉CONNECTIONS与血小板ABSTAMMMENDEN生长因子和/或PDGF和LCK酪氨酸激酶抑制
公开(公告)号：EP0991628A4
公开(公告)日：2000-07-26
申请号：EP98925022
申请日：1998-05-28
IPC分类号： A61K20060101 , A61K31/47 , A61K31/495 , A61K31/498 , A61K31/5377 , A61P9/00 , A61P9/10 , A61P17/06 , A61P19/08 , A61P29/00 , A61P35/00 , A61P35/02 , A61P43/00 , C07D20060101 , C07D215/20 , C07D215/38 , C07D241/42 , C07D241/44 , C07D241/52 , C07D241/54 , C07D403/04 , C07D405/10 , C07D405/12 , C07D453/06
CPC分类号： C07D215/38 , C07D215/20 , C07D241/42 , C07D241/44 , C07D241/52 , C07D241/54 , C07D403/04 , C07D405/12 , C07D453/06
摘要： This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor or p56 tyrosine kinase activity, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
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