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公开(公告)号：EP3253394A1
公开(公告)日：2017-12-13
申请号：EP16746227.4
申请日：2016-01-31
发明人： LEVENBERG, Shulamit , PITARU, Sandu , OFFEN D, Daniel , GANZ, Javier , COHEN-MATSLIAH, Sivan Ida , SHOR, Erez
CPC分类号： A61K35/38 , A61K9/0085 , A61L27/26 , A61L27/3604 , A61L27/3675 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/64 , A61L2430/32 , A61L2430/38 , C12N5/0632 , C12N2533/40 , C12N2533/56
摘要： A method of treating a spinal cord injury in a subject in need thereof is disclosed. The method comprises implanting a scaffold into the spinal cord of a subject, wherein the scaffold is seeded with oral mucosa stem cells (OMSC) and/or cells that have been ex vivo differentiated from said OMSCs, thereby treating the spinal cord injury.
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公开(公告)号：EP2384205A1
公开(公告)日：2011-11-09
申请号：EP09809003.8
申请日：2009-12-31
发明人： PITARU, Sandu , SAVION, Naphtali
CPC分类号： A61L27/225 , A61K38/363 , A61K38/4833 , A61K45/06 , C07K14/75 , C08H1/00 , C08L89/00 , A61K2300/00
摘要： There is provided compositions-of-matter comprising fibrin or fibrinogen crosslinked with at least one reducing sugar.
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4.发明授权
公开(公告)号：EP2137300B1
公开(公告)日：2011-10-26
申请号：EP08738220.6
申请日：2008-04-16
发明人： PITARU, Sandu
CPC分类号： C12N5/0607 , A61K35/38 , C12N5/0632
摘要： The present invention provides a new readily accessible source of adult somatic stem cells from the gastrointestinal tract in general and oral mucosa in particular, methods for isolating pluripotent stem cells from oral mucosa, cells derived therefrom and uses thereof.
摘要翻译： 本发明提供了一般来说，来自胃肠道和口腔粘膜的成熟体细胞干细胞的新的容易获得的来源，特别是从口腔粘膜分离多能干细胞的方法，由其衍生的细胞及其用途。
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5.发明公开STEM CELL-DERIVED NEURAL CELLS FOR CELL THERAPY IN NEUROLOGICAL DISORDERS 审中-公开从得到神经细胞，以神经系统疾病细胞治疗干细胞
公开(公告)号：EP2782587A1
公开(公告)日：2014-10-01
申请号：EP12852394.1
申请日：2012-11-21
发明人： PITARU, Sandu , GANZ, Javier , OFFEN, Daniel , MELAMED, Eldad
IPC分类号： A61K35/12 , A61K48/00 , C12N5/0797
CPC分类号： A61K35/30 , A61K2035/124 , C12N5/0619 , C12N5/0622 , C12N2500/38 , C12N2500/90 , C12N2501/01 , C12N2501/11 , C12N2501/115 , C12N2501/119 , C12N2501/13 , C12N2501/135 , C12N2501/41 , C12N2501/415 , C12N2501/999 , C12N2506/097
摘要： The present invention provides methods and uses of neural cells differentiated from adult stem cells of the oral mucosa for cell therapy of neurological and psychiatric diseases and disorders. Methods for direction of differentiation of oral mucosal stem cells into neuronal or neuron supporting cells are also provided.
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公开(公告)号：EP2137300A1
公开(公告)日：2009-12-30
申请号：EP08738220.6
申请日：2008-04-16
发明人： PITARU, Sandu
CPC分类号： C12N5/0607 , A61K35/38 , C12N5/0632
摘要： The present invention provides a new readily accessible source of adult somatic stem cells from the gastrointestinal tract in general and oral mucosa in particular, methods for isolating pluripotent stem cells from oral mucosa, cells derived therefrom and uses thereof.
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