公开(公告)号：EP1863757A2

公开(公告)日：2007-12-12

申请号：EP06738196.2

申请日：2006-03-14

申请人： Renovis, Inc.

发明人： KELLY, Michael, G. ,  KINCAID, John ,  JANAGANI, Satyanarayana ,  DUNCTON, Matthew, Alexander, James

IPC分类号： C07C239/00 ,  C07C237/00 ,  C07D213/02 ,  A61K31/44 ,  A61K31/505

CPC分类号： C07C233/65 ,  A61K31/165 ,  A61K31/428 ,  A61K31/4412 ,  A61K31/4706 ,  C07C233/75 ,  C07C2601/02 ,  C07C2602/10 ,  C07D213/75 ,  C07D215/38 ,  C07D277/62 ,  C07D319/18

摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

公开(公告)号：EP2139334A1

公开(公告)日：2010-01-06

申请号：EP08742430.5

申请日：2008-03-31

申请人： Renovis, Inc.

发明人： WEI, Zhi-Liang ,  DUNCTON, Matthew, Alexander, James ,  KINCAID, John ,  KELLY, Michael G. ,  O'MAHONY, Donogh ,  WANG, Zhan

IPC分类号： A01N43/90 ,  A61K31/517 ,  C07D471/04

CPC分类号： C07D471/04 ,  C07D519/00

摘要： Fused heterocyclic compounds are provided according to formula (1): where R1, R2, R3, and m are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

公开(公告)号：EP2215054B1

公开(公告)日：2011-08-31

申请号：EP08850350.3

申请日：2008-11-13

申请人： Renovis, Inc. ,  Pfizer Global Research and Development

发明人： COX, Matthew ,  O'MAHONY, Donogh John, Roger ,  ESTIARTE-MARINEZ, Maria, De Los Angeles ,  KAWASHIMA, Tadashi ,  NAGAYAMA, Satoshi ,  SHISIDO, Yuji ,  TANAKA, Hirotaka ,  DUNCTON, Matthew, Alexander, James ,  CALABRESE, Andrew, Antony

IPC分类号： C07C311/08 ,  C07D239/72 ,  C07D239/94 ,  C07D401/12 ,  C07D471/04 ,  A61K31/18 ,  A61K31/47 ,  A61K31/436 ,  A61K31/497

CPC分类号： C07D215/48 ,  C07C311/08 ,  C07C2602/10 ,  C07D265/36 ,  C07D311/58 ,  C07D311/66 ,  C07D319/20 ,  C07D405/04

摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

公开(公告)号：EP2215054A1

公开(公告)日：2010-08-11

申请号：EP08850350.3

申请日：2008-11-13

申请人： Renovis, Inc. ,  Pfizer Global Research and Development

发明人： COX, Matthew ,  O'MAHONY, Donogh John, Roger ,  ESTIARTE-MARINEZ, Maria, De Los Angeles ,  KAWASHIMA, Tadashi ,  NAGAYAMA, Satoshi ,  SHISIDO, Yuji ,  TANAKA, Hirotaka ,  DUNCTON, Matthew, Alexander, James ,  CALABRESE, Andrew, Antony

IPC分类号： C07C311/08 ,  C07D239/72 ,  C07D239/94 ,  C07D401/12 ,  C07D471/04 ,  A61K31/18 ,  A61K31/47 ,  A61K31/436 ,  A61K31/497

CPC分类号： C07D215/48 ,  C07C311/08 ,  C07C2602/10 ,  C07D265/36 ,  C07D311/58 ,  C07D311/66 ,  C07D319/20 ,  C07D405/04

摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

摘要翻译： 公开了具有由下式表示的化学式的化合物：所述化合物可以制备成药物组合物，并且可以用于预防和治疗包括人在内的哺乳动物的多种病症，包括作为非限制性实例的疼痛 ，炎症，创伤性损伤等。