摘要:
This invention is in the field of the injection of liquid into tissue by generating a high pressure jet capable of passing through the skin. It is concerned with a hypodermic injection system for liquids comprising a medication container in which the liquid to be injected is located and which has two regions whereby the first region is squeezable or flexible and the second region contains at least one exiting orifice through which liquid can escape. The flexible region can be deformed by a pressure change in a surrounding container generated by an activatable gas generator and liquid is forced through at least one exiting orifice from the first container. This invention is also directed to means for controlling the pressure of the liquid jet as well as medication containers which enable a sterile injection of medication.
摘要:
This invention is in the field of the injection of liquid into tissue by generating a high pressure jet capable of passing through the skin. It is concerned with a hypodermic injection system for liquids comprising a medication container in which the liquid to be injected is located and which has two regions whereby the first region is squeezable or flexible and the second region contains at least one exiting orifice through which liquid can escape. The flexible region can be deformed by a pressure change in a surrounding container generated by an activatable gas generator and liquid is forced through at least one exiting orifice from the first container. This invention is also directed to means for controlling the pressure of the liquid jet as well as medication containers which enable a sterile injection of medication.
摘要:
Die Erfindung betrifft ein Mikrosampler-Stechsystem zur Entnahme einer Körperflüssigkeitsprobe aus einem Körperteil, umfassend eine Probenentnahmeeinheit mit einem Stechelement, und ein Stechgerät mit einem Antrieb, mittels dem eine Probenentnahmeeinheit auf einem Bewegungsweg beweglich ist, um das Stechelement mit einer Einstich- und Rückführbewegung in die Haut des Körperteils einzustechen und wieder herauszuziehen, einer Einstelleinrichtung zum Einstellen der Einstechtiefe der zu erzeugenden Einstichwunde, und einer Steuereinrichtung zum Steuern der Einstich- und Rückführbewegung mit folgenden nacheinander ablaufenden Bewegungsphasen: Einer Vortriebsphase (V), bei der das Stechelement (5) bis zu einer vorgegebenen Einstechtiefe (dm) eingestochen wird, einer Rückzugsphase (R1), bei der das Stechelement (5) um eine Rückzugsstrecke (Δd) teilweise zurückgezogen und gegen Ende der Rückzugsphase (R1) abgebremst wird, so daß es mit einer vorgegebenen Reststechtiefe (dr) in die Haut hineinragt und einer Sammelphase (S), in der das Stechelement in die Haut hineinragt und eine Körperflüssigkeitsprobe von der Probenaufnahmeeinheit aufgenommen wird. Erfindungsgemäß ist vorgesehen, daß die Einstelleinrichtung derart ausgebildet ist, daß die Einstechtiefe unabhängig von dem zeitlichen Mittel der sich während der Sammelphase (S) ergebenden Reststechtiefe (dr) einstellbar ist.
摘要:
An easy, precise and low-cost manufacturing of a pyrotechnically driven needle-free liquid jet injection device for performing a needleless hypodermic injection of a liquid medication contained in the device into a body, said device comprising a driving unit including pyrotechnical means for generating within the device a pressure necessary for injecting the medication, said means comprising a gas generating pyrotechnical material and an actuation device for igniting the pyrotechnical material, is achieved by said injection device comprising a one-piece ductile pressure shell surrounding at least a portion of the pyrotechnical material, said pressure shell being formed by a single deep-drawn material, preferably metal, as basic construction material for the shell.
摘要:
A needleless hypodermic injection system for injecting a liquid medication, which system comprises a disposable cartridge which contains a medication and which includes a propellant and an igniter, and a reusable application device which comprises a pressure chamber for receiving the medication cartridge, actuation means including an ignition system and means for ensuring reliability and safety of the system. The reusable application device comprises:
(a) a housing including a fist housing section and a second housing section which are adapted to be assembled together by a screwing operation, the first housing section comprising a front part having an injection outlet and a chamber adapted to receive a the cartridge contains the medication to be injected and also contains a propellant and an igniter, and (b) means for selectively activating said igniter of said cartridge when predetermined conditions are fulfilled.
摘要:
The present invention concerns a system for sampling body fluids, comprising an implantable catheter for introduction into tissue, a pump means for transporting a volume of said body fluid out of the catheter, a volume determination unit for determining said volume of fluid and a control means (70) for controlling the pump means based on the determined volume of body fluid. Alternatively to volume determination and control the invention proposes to sample with an overall flow rate of below 10 nanoliters per minute or to sample below 50 nanoliters per sampling event.
摘要:
A hypodermic needleless injection system for injecting a liquid medication, which system comprises:
(a) a medication unit configured and dimensioned to store a volume of liquid to be injected, the medication unit having a first region and a second region that are in liquid communication with each other, the first region being deformable and the second region having at least one orifice, (b) a hydrostatic chamber containing a hydrostatic pressure transfer medium, the hydrostatic chamber being so configured and dimensioned that the medication unit is located at least partially within the hydrostatic chamber and so that a pressure exerted on the transfer medium would cause the first region of the medication unit to deform so as to reduce the volume available for the liquid medication within the medication unit, and (c) a first piston having a first end and a second end opposite to the first end, the first end having a surface which forms a closure of the hydrostatic chamber, and is adapted for applying a pressure on the transfer medium contained in the hydrostatic chamber.