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1.
公开(公告)号:EP1038024A1
公开(公告)日:2000-09-27
申请号:EP98966274.7
申请日:1998-12-09
发明人: NAGEL, Rolf , MISTELE, Jürgen , SCHRÖDER, Norbert
IPC分类号: C12Q1/50
CPC分类号: C12Q1/50
摘要: A stabilised reagent for photometric enzymatic determination of creatine kinase (CK) in biological sample material by forming ATP from creatine phosphate and ADP and detection of the ATP thus formed containing an organic or inorganic sulphur compound, preferably with a molar deficiency in relation to the added CK activator. A corresponding reagent remains stable at 2-8 °C for up to 12 months without incurring any significant functional loss.
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公开(公告)号:EP3918087A1
公开(公告)日:2021-12-08
申请号:EP20701641.1
申请日:2020-01-30
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公开(公告)号:EP2467478A1
公开(公告)日:2012-06-27
申请号:EP10757053.3
申请日:2010-08-18
发明人: RÖDEL, Wolfgang , HORN, Carina , STEINKE, Nelli , BUCCI, Nadine , MEIER, Thomas , SCHMUCK, Rainer , NAGEL, Rolf , HEINDL, Dieter
CPC分类号: C12N9/96 , C12N9/0006 , C12N9/0036 , C12Q1/26 , C12Q1/32 , C12Y101/01001 , C12Y101/01002 , C12Y101/01047 , C12Y101/01049 , C12Y106/05002 , C12Y106/99
摘要: The present invention relates to a method for stabilizing an enzyme by storing an enzyme in the presence of a stabilized coenzyme. The present invention further relates to an enzyme stabilized with a stabilized coenzyme and to the use thereof in test elements for detecting analytes.
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公开(公告)号:EP2467478B1
公开(公告)日:2015-09-16
申请号:EP10757053.3
申请日:2010-08-18
发明人: RÖDEL, Wolfgang , HORN, Carina , STEINKE, Nelli , BUCCI, Nadine , MEIER, Thomas , SCHMUCK, Rainer , NAGEL, Rolf , HEINDL, Dieter
IPC分类号: C12N9/04
CPC分类号: C12N9/96 , C12N9/0006 , C12N9/0036 , C12Q1/26 , C12Q1/32 , C12Y101/01001 , C12Y101/01002 , C12Y101/01047 , C12Y101/01049 , C12Y106/05002 , C12Y106/99
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5.
公开(公告)号:EP1038024B1
公开(公告)日:2007-06-13
申请号:EP98966274.7
申请日:1998-12-09
发明人: NAGEL, Rolf , MISTELE, Jürgen , SCHRÖDER, Norbert
IPC分类号: C12Q1/50
CPC分类号: C12Q1/50
摘要: A stabilised reagent for photometric enzymatic determination of creatine kinase (CK) in biological sample material by forming ATP from creatine phosphate and ADP and detection of the ATP thus formed containing an organic or inorganic sulphur compound, preferably with a molar deficiency in relation to the added CK activator. A corresponding reagent remains stable at 2-8 DEG C for up to 12 months without incurring any significant functional loss.
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