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1.发明授权ELECTRODE SYSTEM FOR MEASURING AN ANALYTE CONCENTRATION UNDER IN-VIVO CONDITIONS 有权电极系统用于测量分析浓度下在体内条件
公开(公告)号：EP2348964B1
公开(公告)日：2013-05-15
申请号：EP09812678.2
申请日：2009-05-27
发明人： QUARDER, Ortrud , MISCHLER, Reinhold , RIEGER, Ewald , STAIB, Arnulf , GILLEN, Ralph , KAMECKE, Ulrike
IPC分类号： A61B5/145 , A61B5/1486
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/7207 , C12Q1/001 , C12Q1/006
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公开(公告)号：EP1865846B1
公开(公告)日：2015-08-12
申请号：EP06723174.6
申请日：2006-03-02
发明人： DECK, Frank , QUARDER, Ortrud , WEISS, Thomas , HÖRAUF, Christian , KEIL, Michael , KONYA, Ahmet , HARTTIG, Herbert , BAADER, Felix , LIST, Hans , EBERT, Karl-Peter
IPC分类号： A61B5/151
CPC分类号： A61B5/15148 , A61B5/150022 , A61B5/15019 , A61B5/150198 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/150832 , A61B5/150916 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/15194 , A61B5/15196
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公开(公告)号：EP1865846A2
公开(公告)日：2007-12-19
申请号：EP06723174.6
申请日：2006-03-02
发明人： DECK, Frank , QUARDER, Ortrud , WEISS, Thomas , HÖRAUF, Christian , KISTNER, Michael , KONYA, Ahmet , HARTTIG, Herbert , BAADER, Felix , LIST, Hans , EBERT, Karl-Peter
IPC分类号： A61B5/151
CPC分类号： A61B5/15148 , A61B5/150022 , A61B5/15019 , A61B5/150198 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/150832 , A61B5/150916 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/15194 , A61B5/15196
摘要： The invention relates to a piercing system for removing bodily fluid from the skin of a human or animal. Said system comprises a disposable piercing unit (1), which contains a needle element (6) for puncturing the skin, a piercing device (2), which encompasses a piercing drive (4), said drive propelling a piercing displacement of the piercing unit (1), which is coupled to the piercing drive (4) by means of a coupling mechanism (3), a predefined value of the piercing depth being guaranteed using a piercing depth reference element (10), which comprises a skin contact surface (11) and the predefined value of the piercing depth being determined by the distance in the piercing direction between the skin contact surface (11) and the position of the needle tip at the inversion point of the piercing displacement. The piercing depth reference element (10) is connected to the needle element (6) and coupled to the drive in such a way that it is displaced together with the needle element (1) during at least one part of the propulsion phase and has a defined longitudinal position in the piercing direction in relation to the needle element (6), at least at the inverse point of the piercing displacement.
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4.发明公开ELECTRODE SYSTEM FOR MEASURING AN ANALYTE CONCENTRATION UNDER IN-VIVO CONDITIONS 有权电极系统用于测量分析浓度下在体内条件
公开(公告)号：EP2348964A1
公开(公告)日：2011-08-03
申请号：EP09812678.2
申请日：2009-05-27
发明人： QUARDER, Ortrud , MISCHLER, Reinhold , RIEGER, Ewald , STAIB, Arnulf , GILLEN, Ralph , KAMECKE, Ulrike
IPC分类号： A61B5/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/7207 , C12Q1/001 , C12Q1/006
摘要： The invention relates to an electrode system for measuring the concentration of an analyte under in-vivo conditions, comprising a counter-electrode (2) having an electrical conductor (2a), a working electrode (1) having an electrical conductor (1a) on which an enzyme layer (5) containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules down. The invention provides the enzyme layer (5) in the form of multiple fields that are arranged on the conductor (1a) of the working electrode (1 ) at a distance from each other.
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5.发明公开VERFAHREN UND VORRICHTUNG ZUR BESTIMMUNG DER GLUCOSE-KONZENTRATION IN GEWEBEFLÜSSIGKEIT 审中-公开方法和设备，用于确定葡萄糖浓度组织液
公开(公告)号：EP1879494A2
公开(公告)日：2008-01-23
申请号：EP06742798.9
申请日：2006-05-04
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14528 , A61B5/1473
摘要： The invention relates to a method and a device for determining the glucose concentration in tissue liquid (40). Said method and device are used for detecting (sensor 12) measured values for glucose and an endogenous reference substance in a sample liquid (42) obtained by means of microdialysis, microperfusion, or ultrafiltration (probe 10) and correcting the glucose value in accordance with the measured value for the reference substance. The invention is characterized in that the glucose recovery rate is determined from a non-linear correlation with the recovery rate for the ionic reference substance while the measured value for glucose is corrected therewith. Furthermore, the lactate concentration and/or pyruvate concentration is/are used as (an) additional reference substance(s) in the sample liquid to make further corrections.
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公开(公告)号：EP2661741B1
公开(公告)日：2019-04-17
申请号：EP11808833.5
申请日：2011-12-22
发明人： STAIB, Arnulf , QUARDER, Ortrud , WERNER, Gerhard
IPC分类号： G09B23/00
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公开(公告)号：EP2661741A2
公开(公告)日：2013-11-13
申请号：EP11808833.5
申请日：2011-12-22
发明人： STAIB, Arnulf , QUARDER, Ortrud , WERNER, Gerhard
IPC分类号： G09B23/00
CPC分类号： G06F19/70 , G01N2800/00 , G06F19/00 , G09B23/28
摘要： The method involves providing a set of measured data with a series of measured data of the glucose concentration and a series of measured values of another analyte concentration. A value of a similarity measure is calculated from the series of measured values of the glucose concentration and from one of the multiple predetermined glucose-pattern courses. The value of similarity measure quantifies the similarity between the temporal course of the series of measured values of the glucose concentration and the pertaining glucose-pattern course. An independent claim is also included for a computer program product computer program product.
摘要翻译： 该方法包括提供一组测量数据与一系列葡萄糖浓度的测量数据和另一分析物浓度的一系列测量值。 根据葡萄糖浓度的一系列测量值和多个预定葡萄糖模式级之一计算相似性度量的值。 相似性度量的值量化葡萄糖浓度的一系列测量值的时间过程与相关的葡萄糖模式过程之间的相似性。 计算机程序产品计算机程序产品还包括独立的索赔。
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