摘要:
System and method for the determination of a coagulation parameter comprising a disposable test element (2) and an instrument (1) for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, said non-standard temperature being measured by a temperature measurement device (7) of the instrument, the instrument (1) has a non-volatile memory (18) containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at said non-standard temperature, using said mathematical relationship.
摘要:
System and method for the determination of a coagulation parameter comprising a disposable test element (2) and an instrument (1) for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, said non-standard temperature being measured by a temperature measurement device (7) of the instrument, the instrument (1) has a non-volatile memory (18) containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at said non-standard temperature, using said mathematical relationship.
摘要:
The invention relates to a method for the production of an insulating substrate provided with a layer electrode, in particular for an analytical test strip. A combination of the following method steps is disclosed:- the layer electrode (14) is formed as a structured surface pattern on the substrate (10) and the hydrophilicity of a cover layer (12) on the substrate (10) is increased by a chemical or physical surface treatment.
摘要:
The invention relates to a sampling device for liquid samples, in which the sample is transported in a capillary-active channel from a sampling point to an identification point and the capillary-active channel is substantially configured from a support, a covering and an intermediate layer lying between the support and the covering. The support extends over the covering in the vicinity of the sampling point and the intermediate layer is recessed away from the sampling point in the vicinity of the latter. The device permits both a top dosing of the sample onto the exposed area of the support in the vicinity of the sampling point and a side dosing of said sample.
摘要:
The invention relates to a method, to a test element (50), and to a device (190) for determining at least one concentration of at least one analyte in a sample (110), in particular for detecting at least one metabolite in a sample (110) of a bodily fluid, wherein at least one test element (50) having at least one test chemistry (102) is used, wherein at least one reaction of the test chemistry (102) with the analyte is detected. The invention further relates to at least one marker (104, 104'), wherein the marker (104, 104') is different from the analyte (117), wherein at least one diffusion of the marker (104, 104') in the sample (110) or at least one component of the sample (110) is detected. At least one piece of correction information is produced from the diffusion of the marker (104, 104'), wherein the concentration of the analyte is determined from the reaction of the test chemistry (102) with the analyte while taking into account the correction information.
摘要:
The invention relates to a method for the production of an insulating substrate provided with a layer electrode, in particular for an analytical test strip. A combination of the following method steps is disclosed:- the layer electrode (14) is formed as a structured surface pattern on the substrate (10) and the hydrophilicity of a cover layer (12) on the substrate (10) is increased by a chemical or physical surface treatment.
摘要:
A method for detecting at least one analyte in a body fluid (112) is disclosed. The method comprises the following steps: a) performing an optical measurement, wherein at least one test chemical (120) is contacted with the body fluid (112), wherein the test chemical (120) is an optical test chemical (120) and is adapted to perform at least one detection reaction in the presence of the analyte, wherein at least one optically detectable property of at least one of the body fluid (112) and the test chemical (120) is changed due to the detection reaction, wherein at least one optical measurement value is generated; b) performing at least one impedance measurement, wherein at least two impedance measurement electrodes (130) are used, wherein at least one alternating electrical signal is applied to the body fluid (112) via the impedance measurement electrodes (130) and wherein at least one answer signal is recorded, wherein at least one impedance measurement value is generated; c) performing at least one evaluation step, wherein, in the evaluation step, at least one evaluation algorithm is used, wherein the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid (112).
摘要:
Electrochemical biosensor analysis system for analysing a liquid sample, in particular a body fluid. Said system comprises a biosensor (2), which is intended to be used once and has an electrode structure (16) comprising at least two electrodes (17, 18), a test field which covers the electrode structure (16) and is suitable for receiving the liquid sample and a defined sample feed surface on the top side of the test field, and an evaluation device having an evaluation unit for determining the desired analytical data. The electrode structure is homogeneously distributed on an effective electrode structure surface (23), which can be wetted by the liquid sample, with respect to a resistance measurement on a liquid layer having a defined conductivity and layer thickness. The test field is designed in such a manner that a drop of the liquid sample spreads at least over a partial area of the sample feed surface and a corresponding partial area of the effective electrode structure surface (23) is wetted. The evaluation device has an impedance measuring device in order to measure an impedance measured value between two electrodes (17, 18) of the electrode structure (16) using an area compensation measurement, wherein the measured impedance measured value is used as a measure of the partial area of the effective electrode structure surface (23) which is wetted by the liquid sample when determining the analytical data.
摘要:
The invention relates to a method for the production of an insulating substrate provided with a layer electrode, in particular for an analytical test strip. A combination of the following method steps is disclosed:- the layer electrode (14) is formed as a structured surface pattern on the substrate (10) and the hydrophilicity of a cover layer (12) on the substrate (10) is increased by a chemical or physical surface treatment.
摘要:
The invention relates to a sampling device for liquid samples, in which the sample is transported in a capillary-active channel from a sampling point to an identification point and the capillary-active channel is substantially configured from a support, a covering and an intermediate layer lying between the support and the covering. The support extends over the covering in the vicinity of the sampling point and the intermediate layer is recessed away from the sampling point in the vicinity of the latter. The device permits both a top dosing of the sample onto the exposed area of the support in the vicinity of the sampling point and a side dosing of said sample.