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11 条记录 (耗时 0.015 秒)

    VERFAHREN ZUR BESTIMMUNG EINER ANALYTKONZENTRATION
    2.
    发明公开
    VERFAHREN ZUR BESTIMMUNG EINER ANALYTKONZENTRATION 审中-公开
    方法用于确定分析物浓度

    公开(公告)号：EP2794909A1

    公开(公告)日：2014-10-29

    申请号：EP12805708.0

    申请日：2012-12-20

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： HORN, Carina ,  UNKRIG, Volker

    IPC分类号： C12Q1/54 ,  G01N33/52 ,  A61B5/145

    CPC分类号： C12Q1/54 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1486 ,  A61B2562/0295 ,  G01N21/78 ,  G01N21/8483 ,  G01N33/525 ,  G01N2021/7786 ,  G01N2035/00108

    摘要： The invention relates to a method, to a test element (50), and to a device (190) for determining at least one concentration of at least one analyte in a sample (110), in particular for detecting at least one metabolite in a sample (110) of a bodily fluid, wherein at least one test element (50) having at least one test chemistry (102) is used, wherein at least one reaction of the test chemistry (102) with the analyte is detected. The invention further relates to at least one marker (104, 104'), wherein the marker (104, 104') is different from the analyte (117), wherein at least one diffusion of the marker (104, 104') in the sample (110) or at least one component of the sample (110) is detected. At least one piece of correction information is produced from the diffusion of the marker (104, 104'), wherein the concentration of the analyte is determined from the reaction of the test chemistry (102) with the analyte while taking into account the correction information.

    METHOD AND SYSTEM FOR DETECTING AN ANALYTE IN A BODY FLUID
    4.
    发明公开
    METHOD AND SYSTEM FOR DETECTING AN ANALYTE IN A BODY FLUID 审中-公开
    VERFAHREN UND系统FÜRDEN NACHWEIS EINESTEN IN EINERKÖRPERFLÜSSIGKEIT

    公开(公告)号：EP3008454A1

    公开(公告)日：2016-04-20

    申请号：EP14708819.9

    申请日：2014-02-24

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： BAUER-ESPINDOLA, Klaus Andreas ,  HORN, Carina ,  MARQUANT, Michael ,  NORTMEYER, Christine ,  UNKRIG, Volker

    IPC分类号： G01N21/84 ,  G01N21/64 ,  G01N27/327 ,  G01N27/02

    CPC分类号： G01N33/492 ,  G01N21/6428 ,  G01N21/78 ,  G01N21/8483 ,  G01N27/02 ,  G01N27/12 ,  G01N27/3274 ,  G01N2021/7786

    摘要： A method for detecting at least one analyte in a body fluid (112) is disclosed. The method comprises the following steps: a) performing an optical measurement, wherein at least one test chemical (120) is contacted with the body fluid (112), wherein the test chemical (120) is an optical test chemical (120) and is adapted to perform at least one detection reaction in the presence of the analyte, wherein at least one optically detectable property of at least one of the body fluid (112) and the test chemical (120) is changed due to the detection reaction, wherein at least one optical measurement value is generated; b) performing at least one impedance measurement, wherein at least two impedance measurement electrodes (130) are used, wherein at least one alternating electrical signal is applied to the body fluid (112) via the impedance measurement electrodes (130) and wherein at least one answer signal is recorded, wherein at least one impedance measurement value is generated; c) performing at least one evaluation step, wherein, in the evaluation step, at least one evaluation algorithm is used, wherein the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid (112).

    摘要翻译： 公开了一种用于检测体液中的至少一种分析物的方法，包括执行光学测量，其中至少一种测试化学品接触体液。 测试化学品是适于进行至少一种检测反应的光学测试化学品，其中由于检测反应而改变至少一种可光学检测的性质以提供至少一种光学测量值。 产生至少一个阻抗测量，其中经由阻抗测量电极将至少一个交流电信号施加到体液，并记录至少一个应答信号，并且产生至少一个阻抗测量值。 执行至少一个评估步骤，其中使用至少一个评估算法，并且使用光学测量值和阻抗测量值来确定体液中分析物的浓度。

    ELEKTROCHEMISCHES BIOSENSOR-ANALYSESYSTEM
    5.
    发明公开
    ELEKTROCHEMISCHES BIOSENSOR-ANALYSESYSTEM 有权
    生物传感器分析系统

    公开(公告)号：EP1977225A1

    公开(公告)日：2008-10-08

    申请号：EP07702749.8

    申请日：2007-01-13

    申请人： Roche Diagnostics GmbH ,  F.HOFFMANN-LA ROCHE AG

    发明人： MARQUANT, Michael ,  ZAPF, Udo ,  BAINCZYK, Gregor ,  UNKRIG, Volker ,  LUNGU, Mihail-Onoriu ,  KOTZAN, Holger

    IPC分类号： G01N27/30 ,  G01N33/487 ,  G01N27/04 ,  C12Q1/00

    CPC分类号： C12Q1/001 ,  G01N27/3273 ,  G01N27/3274

    摘要： Electrochemical biosensor analysis system for analysing a liquid sample, in particular a body fluid. Said system comprises a biosensor (2), which is intended to be used once and has an electrode structure (16) comprising at least two electrodes (17, 18), a test field which covers the electrode structure (16) and is suitable for receiving the liquid sample and a defined sample feed surface on the top side of the test field, and an evaluation device having an evaluation unit for determining the desired analytical data. The electrode structure is homogeneously distributed on an effective electrode structure surface (23), which can be wetted by the liquid sample, with respect to a resistance measurement on a liquid layer having a defined conductivity and layer thickness. The test field is designed in such a manner that a drop of the liquid sample spreads at least over a partial area of the sample feed surface and a corresponding partial area of the effective electrode structure surface (23) is wetted. The evaluation device has an impedance measuring device in order to measure an impedance measured value between two electrodes (17, 18) of the electrode structure (16) using an area compensation measurement, wherein the measured impedance measured value is used as a measure of the partial area of the effective electrode structure surface (23) which is wetted by the liquid sample when determining the analytical data.

    SYSTEM AND METHOD FOR MEASURING COAGULATION TIME WITHOUT THERMOSTATIC CONTROL
    7.
    发明公开
    SYSTEM AND METHOD FOR MEASURING COAGULATION TIME WITHOUT THERMOSTATIC CONTROL 有权
    系统和方法测量VONKOAGULATIONSZEIT无恒温控制器

    公开(公告)号：EP1588161A1

    公开(公告)日：2005-10-26

    申请号：EP04704993.7

    申请日：2004-01-24

    申请人： Roche Diagnostics GmbH ,  F. Hoffmann-Roche AG

    发明人： HILL, James, L. ,  UNKRIG, Volker ,  RIEGER, Ewald

    IPC分类号： G01N33/49 ,  G01N33/86

    CPC分类号： G01N33/4905 ,  G01N33/86

    摘要： System and method for the determination of a coagulation parameter comprising a disposable test element (2) and an instrument (1) for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, said non-standard temperature being measured by a temperature measurement device (7) of the instrument, the instrument (1) has a non-volatile memory (18) containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at said non-standard temperature, using said mathematical relationship.

    SYSTEM AND METHOD FOR MEASURING COAGULATION TIME WITHOUT THERMOSTATIC CONTROL
    8.
    发明授权
    SYSTEM AND METHOD FOR MEASURING COAGULATION TIME WITHOUT THERMOSTATIC CONTROL 有权
    系统和方法测量VONKOAGULATIONSZEIT无恒温控制器

    公开(公告)号：EP1588161B1

    公开(公告)日：2007-10-24

    申请号：EP04704993.7

    申请日：2004-01-24

    申请人： Roche Diagnostics GmbH ,  F. Hoffmann-Roche AG

    发明人： HILL, James, L. ,  UNKRIG, Volker ,  RIEGER, Ewald

    IPC分类号： G01N33/49 ,  G01N33/86

    CPC分类号： G01N33/4905 ,  G01N33/86

    摘要： System and method for the determination of a coagulation parameter comprising a disposable test element (2) and an instrument (1) for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, said non-standard temperature being measured by a temperature measurement device (7) of the instrument, the instrument (1) has a non-volatile memory (18) containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at said non-standard temperature, using said mathematical relationship.