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1.发明公开CARTRIDGE FOR DISPENSING A FLUID, AUTOMATIC ANALYZER AND METHOD OF ANALYZING A BIOLOGICAL SAMPLE 审中-公开墨盒做出液，自动分析和方法分析生物样品
公开(公告)号：EP3030352A1
公开(公告)日：2016-06-15
申请号：EP14742198.6
申请日：2014-07-18
发明人： BRÜCKNER, Thorsten , BOEHM, Christoph , SPINKE, Jürgen , TAMURA, Terumi , SAKAZUME, Taku , IMAI, Kyoko
IPC分类号： B01L3/02
CPC分类号： G01N35/1002 , B01L3/0268 , B01L3/0286 , B01L2200/04 , B01L2200/0684 , B01L2300/0609 , B01L2300/0832 , B01L2300/123 , B01L2400/0481 , B01L2400/082 , G01N35/1009
摘要： A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid. The reservoir chamber has a fluid outlet. The cartridge further comprises a controllable dispenser component for dispensing a dispensing volume of the fluid from the reservoir chamber. The dispenser component is connected to the fluid outlet of the reservoir. The cartridge further comprises a single compressible fluid pump with a single elastic pumping element and a conduit extending from the fluid pump towards the fluid outlet. The fluid pump discharges a mixing volume of the fluid from the conduit into the reservoir chamber upon compression of the elastic pumping element. The mixing volume depends on the degree of compression of the elastic pumping element. The fluid pump sucks in the mixing volume from the reservoir into the conduit upon decompression of the elastic pumping element.
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公开(公告)号：EP2847551A1
公开(公告)日：2015-03-18
申请号：EP12787720.7
申请日：2012-11-15
发明人： BÖHM, Christoph , KUPSER, Peter , ANTH, Norbert , SPINKE, Jürgen , BRÜCKNER, Thorsten , KLEIN, Timo
IPC分类号： G01F11/02
摘要： A cartridge (100, 414, 502, 502', 502") for dispensing fluid (214, 610) comprising a rotary valve (110). The rotary valve comprises a pumping chamber (118). The rotary valve is operable for rotating a pumping chamber conduit (120) connected with the pumping chamber. The cartridge further comprises a plunger (108) operable for changing the volume of the pumping chamber. The rotary valve and the plunger are operable for being actuated independently. The cartridge further comprises a reservoir (122) for storing the fluid and a reservoir conduit (124) for connecting the reservoir with the rotary valve. The cartridge further comprises an outlet conduit (128) for dispensing the fluid. The rotary valve is operable for rotating the pumping chamber conduit to connect with the outlet conduit or the reservoir conduit.
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3.发明公开CARTRIDGE FOR DISPENSING A FLUID COMPRISING A REAGENT 审中-公开KARTUSCHE ZUR AUSGABE EINERFLÜSSIGKEITMIT EINEM REAGENS
公开(公告)号：EP2847598A1
公开(公告)日：2015-03-18
申请号：EP13721709.7
申请日：2013-05-07
CPC分类号： B01L3/52 , B01L1/00 , B01L3/523 , B01L5/00 , B01L2200/0684 , B01L2200/141 , B01L2300/048 , B01L2300/0681 , B01L2400/086 , G01N35/1002 , Y10T436/11
摘要： The invention provides for a cartridge (100, 202, 202', 202", 400, 600, 800) for dispensing a fluid (104). The cartridge comprises a reservoir chamber (102) operable for receiving the fluid and for receiving a ventilation gas (106). The reservoir chamber comprises an inlet (114) for receiving the ventilation gas and an outlet (116) for dispensing the fluid. At least a portion (106) of the reservoir chamber is operable for being filled with the ventilation gas when in an operating position. The inlet is located in the portion operable for being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle means (108, 406, 602, 802) for restricting gas diffusion through the inlet. The reservoir chamber is operable for receiving the ventilation gas via the baffle means.
摘要翻译： 本发明提供一种用于分配流体（104）的药筒（100,202,202'，202“，400,600,800），所述药筒包括储存室（102），其可操作用于接收流体并用于接收通气 气体（106），储存室包括用于接收通气气体的入口（114）和用于分配流体的出口（116），储存室的至少一部分（106）可操作以填充通气气体 当处于操作位置时，入口位于可操作以填充通气气体的部分中，流体包括试剂，该滤芯还包括挡板装置（108,406,602,802），用于限制气体扩散通过 储存室可操作以经由挡板装置接收通气气体。
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4.发明公开METHOD TO PERFORM A MEASUREMENT OF AN ANALYTE IN A SAMPLE USING AN AUTOMATIC ANALYZER 审中-公开方法用于进行分析物进行测量;样品通过自动分析装置
公开(公告)号：EP3055699A1
公开(公告)日：2016-08-17
申请号：EP14777663.7
申请日：2014-10-02
CPC分类号： G01N35/1002 , B01L3/021 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L2200/027 , B01L2200/04 , B01L2300/02 , B01L2300/042 , B01L2300/0609 , B01L2300/0663 , B01L2300/123 , B01L2400/0481 , G01F11/082 , G01F11/086 , G01F11/088 , G01N35/00871 , G01N2035/1034
摘要： The invention provides for a cartridge (100, 200, 300, 500, 500', 500", 602, 602', 602", 1100, 1100', 1200, 1200', 1300, 1300', 1400, 1400', 1600, 1900, 1900', 1900", 2000, 2100, 2200, 2300, 2500, 2600) for dispensing a fluid (123). The cartridge comprises: a rigid portion (102), a flexible bladder (104), and an outlet (108). The outlet is attached to the rigid portion. The rigid portion comprises an inner cavity (116). The outlet is connected to the inner cavity. The rigid portion comprises an opening (114). The opening is connected to the inner cavity. The flexible bladder seals the opening to form a fluid chamber (122) from the inner cavity.
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5.发明授权
公开(公告)号：EP3030352B1
公开(公告)日：2019-03-20
申请号：EP14742198.6
申请日：2014-07-18
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公开(公告)号：EP3155400A1
公开(公告)日：2017-04-19
申请号：EP15728016.5
申请日：2015-06-12
IPC分类号： G01N21/07 , G01N21/64 , G01N33/53 , G01N35/00 , G01N30/60 , G01N15/04 , G01N15/05 , G01N15/06 , B01L3/00 , G01N30/38 , G01N35/04 , G01N21/03
摘要： The invention provides for a cartridge (100) for an automatic analyzer (800). The cartridge is operable for being spun around a rotational axis (106). The cartridge comprises a support structure (102) with a front face (114) perpendicular to the rotational axis (106); a fluidic structure for processing a biological sample into the processed biological sample; a measurement structure (402) with at least one detection zone (1100) on the front face; and a rotatable lid (104) covering the front face. The rotatable lid is rotatable about the rotational axis relative to the support structure. The rotatable lid can be rotated from a first position relative to the support structure to a second position relative to the support structure. The rotatable lid has a sample inlet opening (202, 300). The rotatable lid has a detection zone opening (412). In the first position a sample inlet is aligned with the sample inlet opening and the measurement structure is covered by the rotatable lid. In the second position the sample inlet is covered by the rotatable lid and the measurement structure is aligned with the detection zone opening.
摘要翻译： 本发明提供一种用于自动分析器（800）的盒（100）。 盒可操作用于围绕旋转轴线（106）旋转。 盒包括具有垂直于旋转轴线（106）的前表面（114）的支撑结构（102）。 用于将生物样品加工成经处理的生物样品的流体结构; 在前表面上具有至少一个检测区（1100）的测量结构（402） 以及覆盖前表面的可旋转盖（104）。 可旋转盖可相对于支撑结构围绕旋转轴线旋转。 可旋转盖可以相对于支撑结构从第一位置旋转到相对于支撑结构的第二位置。 可旋转盖具有样品入口开口（202,300）。 可旋转盖具有检测区开口（412）。 在第一位置，样品入口与样品入口开口对准，并且测量结构被可旋转的盖子覆盖。 在第二位置，样品入口被可旋转的盖子覆盖，并且测量结构与检测区域开口对准。
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公开(公告)号：EP3155400B1
公开(公告)日：2020-03-04
申请号：EP15728016.5
申请日：2015-06-12
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公开(公告)号：EP2847551B1
公开(公告)日：2020-09-02
申请号：EP12787720.7
申请日：2012-11-15
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公开(公告)号：EP2847598B1
公开(公告)日：2019-02-27
申请号：EP13721709.7
申请日：2013-05-07
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公开(公告)号：EP4023338A1
公开(公告)日：2022-07-06
申请号：EP22152474.7
申请日：2016-04-14
IPC分类号： B01L3/00
摘要： The invention provides for a method of performing an optical measurement (1132) of an analyte in a processed biological sample using a cartridge (100). The cartridge is operable for being spun around a rotational axis (108). The method comprises: placing the biological sample into a sample inlet (112); controlling (1200) the rotational rate of the cartridge to process a biological sample into the processed biological sample using a fluidic structure (110); controlling (1202) the rotational rate of the cartridge to allow the processed biological sample to flow from the measurement structure inlet to an absorbent structure via a chromatographic membrane, and performing (1204) an optical measurement of a detection zone (122) on the chromatographic membrane with an optical instrument. An inlet air baffle reduces evaporation of the processed biological sample from the chromatographic membrane during rotation of the cartridge
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