-
公开(公告)号：EP4153299A1
公开(公告)日：2023-03-29
申请号：EP21732686.7
申请日：2021-05-19
申请人： Rodeo Therapeutics Corporation , Board of Regents of the University of Texas System , Case Western Reserve University
发明人： GWALTNEY, Stephen, L. , READY, Joseph , ANTCZAK, Monika , MARKOWITZ, Sanford, D. , DESAI, Amar , GERSON, Stanton
IPC分类号： A61P1/04 , A61P1/16 , A61P5/44 , A61P9/00 , A61P13/12 , A61P29/00 , A61P35/00 , A61P35/02 , C07D495/04 , C07D519/00 , A61K31/513 , A61K31/517 , A61K31/4985 , A61K31/519 , A61K31/437 , A61K31/5383 , A61K31/506
-
2.发明公开
公开(公告)号：EP3481965A1
公开(公告)日：2019-05-15
申请号：EP17824802.7
申请日：2017-07-05
IPC分类号： C12Q1/68 , G01N33/574
-
-
公开(公告)号：EP1660683B1
公开(公告)日：2017-04-19
申请号：EP04781201.1
申请日：2004-08-16
CPC分类号： G01N33/57419 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/154 , G01N33/5011
-
5.发明公开METHODS AND COMPOSITIONS FOR DETECTING COLON CANCERS 有权VERFAHREN UND ZUSAMMENSETZUNGEN ZUM NACHWEIS VON KOLONKARZINOMEN
公开(公告)号：EP1660683A2
公开(公告)日：2006-05-31
申请号：EP04781201.1
申请日：2004-08-16
CPC分类号： G01N33/57419 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/154 , G01N33/5011
摘要： This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia.
摘要翻译： 本申请描述了用于检测和治疗波形蛋白相关瘤形成的方法和组合物。 波形蛋白核苷酸序列的差异甲基化已经在波形蛋白相关性肿瘤如结肠瘤形成中被观察到。
-
公开(公告)号：EP2198306A1
公开(公告)日：2010-06-23
申请号：EP08795768.4
申请日：2008-09-05
IPC分类号： G01N33/574 , G01N33/68 , C12Q1/68
CPC分类号： G01N33/57407 , C12Q1/6886 , C12Q2600/158 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N33/57438 , G01N33/57442 , G01N33/57446 , G01N33/57449 , G01N33/57488 , G01N33/6893 , G01N2500/00 , G01N2800/046
摘要： The disclosure provides, among other things, molecular markers for diagnosing neoplasias or categorizing the neoplastic state of a patient. The disclosure also provides methods for using the molecular markers in designing, screening and targeting therapeutic agents for the treatment of cancers.
-
公开(公告)号：EP1576109A2
公开(公告)日：2005-09-21
申请号：EP03754420.2
申请日：2003-08-26
IPC分类号： C12N1/00
CPC分类号： C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/158 , G01N33/57419
摘要： The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in diagnostic tests, nucleic acid and amino acid sequences related to the molecular markers, reagents for detection of molecular markers, and methods for identifying candidate molecular markers in highly parallel gene expression data.
-
公开(公告)号：EP1575993A2
公开(公告)日：2005-09-21
申请号：EP03774462.0
申请日：2003-08-26
IPC分类号： C07K1/00
CPC分类号： C12Q1/6886 , C07K14/4748 , C12Q2600/136 , G01N33/57419 , G01N2500/00
摘要： The disclosure provides, among other things, molecular markers for categorizing the neoplastic state of a patient, methods for using the molecular markers in designing, screening for and targeting .
-
公开(公告)号：EP1551437A2
公开(公告)日：2005-07-13
申请号：EP03757461.3
申请日：2003-06-05
IPC分类号： A61K38/00 , C07K1/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K14/00 , C07K16/00 , C07K17/00
CPC分类号： C12N15/8509 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , C07K14/4702 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , C12Q2600/154
摘要： In certain aspects, the invention provides isolated SLC5A8 (also referred to as Huil) nucleic acid molecules, which encode novel sodium solute symporter members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SLC5A8 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a SLC5A8 gene has been introduced or disrupted. The invention still further provides isolated SLC5A8 proteins, fusion proteins, antigenic peptides, and anti-SLC5A8 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. In other aspects, the invention provides methods and compositions for detecting and treating SLC5A8-associated cancer. Differential methylation of the SLC5A8 nucleotide sequences has been observed in SLC5A8-associated cancer, such as colon cancer, breast cancer, thyroid cancer, or stomach cancer.
-
公开(公告)号：EP3976816A1
公开(公告)日：2022-04-06
申请号：EP20814329.7
申请日：2020-05-28
IPC分类号： C12Q1/6806 , C12N15/10 , A01N1/00
-
-
-
-
-
-
-
-
-
搜索结果
13 条记录 (耗时 0.027 秒)
