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1.发明公开DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS 有权丙型肝炎病毒NS-3 SERINPROTEASES DIARYLREST ENTFASSENDE肽抑制剂
公开(公告)号：EP1343807A2
公开(公告)日：2003-09-17
申请号：EP01986126.9
申请日：2001-12-10
申请人： SCHERING CORPORATION
发明人： ZHU, Zhaoning , SUN, Zhong-Yue , VENKATRAMAN, Srikanth , NJOROGE, F. George, , ARASAPPAN, Ashok , MALCOLM, Bruce A. , GIRIJAVALLABHAN, Viyyoor M. , LOVEY, Raymond G. , CHEN, Kevin X.
IPC分类号： C07K1/00
CPC分类号： C07K5/0202 , A61K38/00 , C07K14/811
摘要： The present invention is directed to certain diaryl amide compounds as NS3-Serine protease inhibitors of hepatitis C virus. A particularly preferred compound is of the formula (I).
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2.发明授权SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 有权硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
公开(公告)号：EP1730110B1
公开(公告)日：2010-06-09
申请号：EP05723607.7
申请日：2005-02-24
申请人： Schering Corporation
发明人： BENNETT, Frank , LOVEY, Raymond G. , HUANG, Yuhua , HENDRATA, Siska , SAKSENA, Anil, K. , BOGEN, Stephane, L. , LIU, Yi-Tsung , NJOROGE, F., George , VENKATRAMAN, Srikanth , CHEN, Kevin, X. , SANNIGRAHI, Mousumi , ARASAPPAN, Ashok , GIRIJAVALLABHAN, Viyyoor, M. , VELAZQUEZ, Francisco , NAIR, Latha
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K5/02 , A61K31/403 , A61K31/407 , A61P31/12
CPC分类号： C07D209/52 , A61K38/00 , C07D207/16 , C07D209/56 , C07D405/12 , C07D409/12 , C07D411/12 , C07D491/04 , C07K5/0202
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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3.发明公开SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 有权硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
公开(公告)号：EP1730110A1
公开(公告)日：2006-12-13
申请号：EP05723607.7
申请日：2005-02-24
申请人： SCHERING CORPORATION
发明人： BENNETT, Frank , LOVEY, Raymond G. , HUANG, Yuhua , HENDRATA, Siska , SAKSENA, Anil, K. , BOGEN, Stephane, L. , LIU, Yi-Tsung , NJOROGE, F., George , VENKATRAMAN, Srikanth , CHEN, Kevin, X. , SANNIGRAHI, Mousumi , ARASAPPAN, Ashok , GIRIJAVALLABHAN, Viyyoor, M. , VELAZQUEZ, Francisco , NAIR, Latha
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K7/02 , A61K31/403 , A61K31/407 , A61P31/12 , C07D307/00 , C07D209/00
CPC分类号： C07D209/52 , A61K38/00 , C07D207/16 , C07D209/56 , C07D405/12 , C07D409/12 , C07D411/12 , C07D491/04 , C07K5/0202
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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4.发明授权SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 有权硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
公开(公告)号：EP1730110B9
公开(公告)日：2011-11-02
申请号：EP05723607.7
申请日：2005-02-24
申请人： Schering Corporation
发明人： BENNETT, Frank , LOVEY, Raymond G. , HUANG, Yuhua , HENDRATA, Siska , SAKSENA, Anil, K. , BOGEN, Stephane, L. , LIU, Yi-Tsung , NJOROGE, F., George , VENKATRAMAN, Srikanth , CHEN, Kevin, X. , SANNIGRAHI, Mousumi , ARASAPPAN, Ashok , GIRIJAVALLABHAN, Viyyoor, M. , VELAZQUEZ, Francisco , NAIR, Latha
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K5/02 , A61K31/403 , A61K31/407 , A61P31/12
CPC分类号： C07D209/52 , A61K38/00 , C07D207/16 , C07D209/56 , C07D405/12 , C07D409/12 , C07D411/12 , C07D491/04 , C07K5/0202
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
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5.发明授权DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS 有权二肽类化合物作为丙型肝炎病毒NS3-丝氨酸蛋白酶抑制剂
公开(公告)号：EP1343807B1
公开(公告)日：2009-04-29
申请号：EP01986126.9
申请日：2001-12-10
申请人： Schering Corporation
发明人： ZHU, Zhaoning , SUN, Zhong-Yue , VENKATRAMAN, Srikanth , NJOROGE, F. George, , ARASAPPAN, Ashok , MALCOLM, Bruce A. , GIRIJAVALLABHAN, Viyyoor M. , LOVEY, Raymond G. , CHEN, Kevin X.
CPC分类号： C07K5/0202 , A61K38/00 , C07K14/811
摘要： The present invention is directed to certain diaryl amide compounds as NS3-Serine protease inhibitors of hepatitis C virus. A particularly preferred compound is of the formula (I).
摘要翻译： 本发明涉及某些二芳基酰胺化合物作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂。 特别优选的化合物是式（I）的化合物。
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