-
1.发明授权New seco-D steroids active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them 失效在心血管系统的活性开环 - D-类固醇，它们的制备方法和含有它们的药物组合物
公开(公告)号：EP0825177B1
公开(公告)日：2000-04-05
申请号：EP97111643.9
申请日：1997-07-09
发明人： Gobbini, Mauro , De Munari, Sergio , Fedrizzi, Giorgio , Ferrari, Patrizia , Melloni, Piero , Santagostino, Marco , Torri, Marco
IPC分类号： C07C251/58 , C07C281/18 , A61K31/15 , A61K31/155
CPC分类号： C07C281/18 , C07C251/58 , C07C2603/26
-
2.发明公开New 6-hydroxy and 6-oxo-anstro-stane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效Neue 6-Hydroxy and 6-Oxo-Androstan Verbindungen mitKardioaktivitätund pharmazeutischePräparatedavon
公开(公告)号：EP0825197A2
公开(公告)日：1998-02-25
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
摘要： 6-Hydroxy and 6-oxo-androstane derivatives having the general formula (I):
wherein the symbol represents a single or a double bond and A, R 1 and R 2 have the meanings given in the description; a pharmaceutical composition comprising the same and their use for the preparation of a medicament useful for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.摘要翻译： 具有通式（I）的6-羟基和6-氧代 - 雄甾烷衍生物：
其中符号@表示单键或双键，A，R 1和R 2具有 描述; 公开了包含其的药物组合物及其用于制备可用于治疗心力衰竭和高血压的心血管疾病的药物的用途。 -
3.发明公开New seco-D steroids active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them 失效在心血管系统的活性开环 - D-类固醇，它们的制备方法和含有它们的药物组合物
公开(公告)号：EP0825177A1
公开(公告)日：1998-02-25
申请号：EP97111643.9
申请日：1997-07-09
发明人： Gobbini, Mauro , De Munari, Sergio , Fedrizzi, Giorgio , Ferrari, Patrizia , Melloni, Piero , Santagostino, Marco , Torri, Marco
IPC分类号： C07C251/58 , C07C281/18 , A61K31/15 , A61K31/155
CPC分类号： C07C281/18 , C07C251/58 , C07C2603/26
摘要： Seco-D steroid derivatives having the general formula (I):
wherein the symbol means α or β configuration and R, R 1 , R 2 and R 3 have the meanings given in the description;
a process for producing the same;
a pharmaceutical composition comprising the same and their use for the preparation of a medicament useful for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.-
4.发明授权New 6-hydroxy and 6-oxo-androstane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效其Kardioaktivität新6-羟基和6-氧代雄甾烷化合物和药物制剂
公开(公告)号：EP0825197B1
公开(公告)日：2000-10-04
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
-
5.发明公开New 6-hydroxy and 6-oxo-anstro-stane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效其Kardioaktivität新6-羟基和6-氧代雄甾烷化合物和药物制剂
公开(公告)号：EP0825197A3
公开(公告)日：1999-04-14
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
摘要： 6-Hydroxy and 6-oxo-androstane derivatives having the general formula (I):
wherein the symbol represents a single or a double bond and A, R 1 and R 2 have the meanings given in the description; a pharmaceutical composition comprising the same and their use for the preparation of a medicament useful for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.
-
-
-
-
搜索结果
5 条记录 (耗时 0.01 秒)
