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1.发明公开Process for the oxidation of primary and secondary alcohols to aldehydes and ketones and for the oxidation of 1,2-diols to alpha-ketols and alpha-diketones 失效一种用于氧化非伯醇和仲醇，以醛和酮和1,2-二醇到的α-酮醇与α-二酮的氧化过程。
公开(公告)号：EP0658533A1
公开(公告)日：1995-06-21
申请号：EP94119234.6
申请日：1994-12-06
IPC分类号： C07C45/30
CPC分类号： C07B41/06 , C07C45/30 , C07D213/48 , C07D307/48 , C07J1/0011 , C07J9/00
摘要： The invention provides a process for the selective oxidation of a primary or secondary alcohol to an aldehyde or ketone and for the oxidation of a 1,2-diol to an α-ketol or α-diketone which comprises contacting the alcohol or 1,2-diol with o-iodoxybenzoic acid.
摘要翻译： 本发明提供了在和1,2-二醇的氧化在的α-乙酮醇或α-二酮其包括使醇或用于伯或仲醇的醛或酮的选择性氧化的方法1,2- 与邻碘酰基苯甲酸二醇。
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2.发明授权Process for the preparation of (E,Z) 3-(2-aminoethoxyimino)-androstane-6,17-dione and its analogues 有权一种用于（E，Z）3-（2-氨基乙氧基亚胺基）甾-6,17二酮及其类似物的制备方法
公开(公告)号：EP1156058B1
公开(公告)日：2007-02-28
申请号：EP01830306.5
申请日：2001-05-14
发明人： Gobbini, Mauro , Carzana, Giulio , Sputore, Simona
CPC分类号： C07J41/0016 , C07J51/00
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3.发明授权Process for the oxidation of primary and secondary alcohols to aldehydes and ketones and for the oxidation of 1,2-diols to alpha-ketols and alpha-diketones 失效一种用于伯醇和仲醇氧化成醛和酮和1,2-二醇到的α-酮醇与α-二酮的氧化过程
公开(公告)号：EP0658533B1
公开(公告)日：1998-04-15
申请号：EP94119234.6
申请日：1994-12-06
IPC分类号： C07C45/30
CPC分类号： C07B41/06 , C07C45/30 , C07D213/48 , C07D307/48 , C07J1/0011 , C07J9/00
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4.发明公开New 6-hydroxy and 6-oxo-anstro-stane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效Neue 6-Hydroxy and 6-Oxo-Androstan Verbindungen mitKardioaktivitätund pharmazeutischePräparatedavon
公开(公告)号：EP0825197A2
公开(公告)日：1998-02-25
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
摘要： 6-Hydroxy and 6-oxo-androstane derivatives having the general formula (I):
wherein the symbol represents a single or a double bond and A, R 1 and R 2 have the meanings given in the description; a pharmaceutical composition comprising the same and their use for the preparation of a medicament useful for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.摘要翻译： 具有通式（I）的6-羟基和6-氧代 - 雄甾烷衍生物：
其中符号@表示单键或双键，A，R 1和R 2具有 描述; 公开了包含其的药物组合物及其用于制备可用于治疗心力衰竭和高血压的心血管疾病的药物的用途。 -
5.发明公开Process for the preparation of (E,Z) 3-(2-aminoethoxyimino)-androstane-6,17-dione and its analogues 有权一种用于（E，Z）3-（2-氨基乙氧基亚胺基）甾-6,17二酮及其类似物的制备方法
公开(公告)号：EP1156058A3
公开(公告)日：2005-06-08
申请号：EP01830306.5
申请日：2001-05-14
发明人： Gobbini, Mauro , Carzana, Giulio , Sputore, Simona
CPC分类号： C07J41/0016 , C07J51/00
摘要： An improved process is described for the preparation of compounds with general formula (I) and particularly for the preparation of the compound (E,Z) 3-(2-aminoethoxyimino)androstane-6,17-dione, in which n = 1 and R 1 = R 2 = H.
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6.发明公开Process for the preparation of (E,Z) 3-(2-aminoethoxyimino)-androstane-6,17-dione and its analogues 有权Verfahren zur Herstellung von（E，Z）3-（2-氨基乙氧基亚氨基） - 雄甾烷-6,17-二酮和分析
公开(公告)号：EP1156058A2
公开(公告)日：2001-11-21
申请号：EP01830306.5
申请日：2001-05-14
发明人： Gobbini, Mauro , Carzana, Giulio , Sputore, Simona
CPC分类号： C07J41/0016 , C07J51/00
摘要： An improved process is described for the preparation of compounds with general formula (I) and particularly for the preparation of the compound (E,Z) 3-(2-aminoethoxyimino)androstane-6,17-dione, in which n = 1 and R 1 = R 2 = H.
摘要翻译： 描述了制备具有通式（I）的化合物，特别是制备化合物（E，Z）3-（2-氨基乙氧基亚氨基）雄甾烷-6,17-二酮的改进方法，其中n = 1和 R 1 = R 2 = H.
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7.发明授权New 6-hydroxy and 6-oxo-androstane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效其Kardioaktivität新6-羟基和6-氧代雄甾烷化合物和药物制剂
公开(公告)号：EP0825197B1
公开(公告)日：2000-10-04
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
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8.发明公开New 6-hydroxy and 6-oxo-anstro-stane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 失效其Kardioaktivität新6-羟基和6-氧代雄甾烷化合物和药物制剂
公开(公告)号：EP0825197A3
公开(公告)日：1999-04-14
申请号：EP97111651.2
申请日：1997-07-09
发明人： De Munari, Sergio , Folpini, Elena , Frigerio, Marco , Melloni, Piero , Serra, Fulvio , Sputore, Simona
IPC分类号： C07J41/00 , A61K31/565 , C07J43/00 , A61K31/58
CPC分类号： C07J41/0038 , C07J41/0016 , C07J43/003
摘要： 6-Hydroxy and 6-oxo-androstane derivatives having the general formula (I):
wherein the symbol represents a single or a double bond and A, R 1 and R 2 have the meanings given in the description; a pharmaceutical composition comprising the same and their use for the preparation of a medicament useful for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.
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