公开(公告)号：EP2868782A4

公开(公告)日：2016-01-20

申请号：EP13810001

申请日：2013-04-26

申请人： SPIBER INC

发明人： ISHIKAWA MIZUKI ,  SEKIYAMA KAZUHIDE

IPC分类号： D01F4/00 ,  C07K14/435 ,  D01D1/02 ,  D01D5/04 ,  D01D5/06 ,  D01F1/06 ,  D01F4/02

CPC分类号： D01F4/02 ,  C07K14/43518 ,  D01D1/02 ,  D01D5/04 ,  D01D5/06 ,  D01F1/06 ,  D01F4/00

摘要： A solution-dyed protein fiber of the present invention includes 0-100 mass% of silk fibroin and 100-0 mass% of a polypeptide derived from spider silk proteins when the protein fiber is assumed to be 100 mass%, wherein the solution-dyed protein fiber contains a solution-dyeing colorant. The fiber is obtained by: dissolving or dispersing a solution-dyeing colorant in a solvent used for a spinning solution or in dimethyl sulfoxide, thereby preparing a coloring liquid; adding a solvent to the coloring liquid in an amount necessary for a spinning solution; adding and dissolving protein powder into the solvent, thereby preparing a spinning solution; and subjecting the spinning solution to wet spinning or dry-wet spinning. Thereby, the present invention provides a low-cost solution-dyed protein fiber in which a solution-dyeing colorant is dispersed uniformly and that can exhibit bright color tone, and a method for producing the same.

摘要翻译： 当蛋白质纤维假定为100质量％时，本发明的溶液染色蛋白质纤维包含0-100质量％的丝素蛋白和100-0质量％的来自蜘蛛丝蛋白的多肽，其中溶液染色 蛋白纤维含有溶染染色剂。 纤维通过以下方法获得：将溶染染色剂溶解或分散在用于纺丝溶液或二甲基亚砜的溶剂中，从而制备着色液体; 以纺丝溶液所需的量向着色液中加入溶剂; 将蛋白粉加入溶解溶剂中，制备纺丝溶液; 并对纺丝溶液进行湿纺或干湿纺丝。 因此，本发明提供了一种低成本的溶染染色蛋白质纤维，其中溶染染色剂均匀分散并且可以表现出明亮的色调，及其制备方法。

公开(公告)号：EP2716798A4

公开(公告)日：2015-03-11

申请号：EP12793074

申请日：2012-05-30

申请人： SPIBER INC

发明人： SEKIYAMA KAZUHIDE ,  SEKIYAMA KAORI ,  ISHIKAWA MIZUKI ,  SATO RYOTA ,  MURATA SHINYA

IPC分类号： D01F4/00 ,  C12P21/02 ,  D01D5/06

CPC分类号： C07K14/43518 ,  D01D5/06 ,  D01D5/16 ,  D01F4/02 ,  D01F6/68

摘要： An artificial polypeptide fiber of the present invention is an artificial fiber containing a polypeptide as a main component, and has a stress of 350 MPa or more and a toughness of 138 MJ/m 3 or more. A method for producing an artificial polypeptide fiber of the present invention is a method for producing the artificial polypeptide fiber obtained by spinning a spinning solution (6) containing a polypeptide derived from natural spider silk proteins and performing drawing of at least two stages. The drawing of at least two stages includes a first-stage drawing (3) in wet heat and a second-stage drawing (4) in dry heat. Thereby, the present invention provides high-toughness artificial polypeptide fibers having favorable stress and rupture elongation, and a method for producing the same.

公开(公告)号：EP2940066A4

公开(公告)日：2016-07-06

申请号：EP13867491

申请日：2013-12-17

申请人： SPIBER INC

发明人： SEKIYAMA KAORI ,  ISHIKAWA MIZUKI ,  MURATA SHINYA

IPC分类号： C08J5/18 ,  B29C39/02 ,  B29C55/02 ,  B29C71/02 ,  B29L7/00 ,  C07K14/435 ,  C08L89/00

CPC分类号： C07K14/43518 ,  B29C39/02 ,  B29C55/02 ,  B29C71/02 ,  B29K2089/00 ,  B29K2867/003 ,  B29K2995/002 ,  B29L2007/008 ,  C08J5/18 ,  C08J2389/00 ,  C08L89/00

摘要： A film of the present invention contains a polypeptide derived from spider silk proteins. The decomposition temperature of the film is 240 to 260°C. The film absorbs ultraviolet light having a wavelength of 200 to 300 nm and has a light transmittance of 85% or more at a wavelength of 400 to 780 nm. The film is transparent and colorless in a visible light region. A method for producing a film of the present invention includes: dissolving a polypeptide derived from spider silk proteins in a dimethyl sulfoxide solvent to prepare a dope; and cast-molding the dope on a surface of a base. Thus, the present invention provides a spider silk protein film that can be formed easily and has favorable stretchability, and a method for producing the same.

公开(公告)号：EP2774934A4

公开(公告)日：2015-05-13

申请号：EP12844908

申请日：2012-10-29

申请人： SPIBER INC

发明人： SUGAHARA JUNICHI ,  SEKIYAMA KAORI ,  SATO RYOTA ,  ISHIKAWA MIZUKI ,  MURATA SHINYA ,  SEKIYAMA KAZUHIDE ,  OTOMO KAZUKO

IPC分类号： C07K14/435 ,  C12N15/09 ,  D01D5/04 ,  D01F4/02

CPC分类号： C08K5/41 ,  B29D99/0078 ,  C07K14/43518 ,  C08K3/16 ,  C08K5/20 ,  D01D5/04 ,  D01F4/02 ,  D01F6/68 ,  Y10S530/858

摘要： A polypeptide solution of the present invention is a polypeptide solution in which a polypeptide derived from natural spider silk proteins is dissolved in a solvent. The solvent contains at least one selected from the following (i)-(ii): (i) DMSO with an inorganic salt; and (ii) DMF with an inorganic salt. Further, in the present invention, an artificial polypeptide fiber is obtained by: using the polypeptide solution as a dope solution; and extruding the dope solution from a spinneret into a desolvation bath so as to eliminate the solvent from the dope solution and form a fiber to produce an undrawn yarn. Moreover, in the present invention, a polypeptide is purified by subjecting the polypeptide solution to heat treatment and thereafter removing an undissolved substance therefrom. Thus, the present invention provides the polypeptide solution whose solute has high solubility and solvent itself is low cost, and that allows dissolution at high temperatures and has high safety: a method for producing an artificial polypeptide fiber: and a method for purifying a polypeptide.

摘要翻译： 本发明的多肽溶液是多肽溶液，其中衍生自天然蜘蛛丝蛋白的多肽溶解在溶剂中。 溶剂含有选自以下（i） - （iii）中的至少一种：（i）DMSO; （ii）具有无机盐的DMSO; 和（iii）具有无机盐的DMF。 此外，在本发明中，通过以下方法获得人造多肽纤维：使用多肽溶液作为掺杂溶液; 并将喷丝头溶液从喷丝头挤出到去溶剂浴中，以从溶剂溶液中除去溶剂，并形成纤维以产生未拉伸的纱线。 此外，在本发明中，通过使多肽溶液进行热处理，然后从其中除去未溶解的物质来纯化多肽。 因此，本发明提供了其溶质具有高溶解度的多肽溶液，本身的溶剂本身是低成本的，并且允许在高温下溶解并且具有高安全性：制备人造多肽纤维的方法和纯化多肽的方法。