公开(公告)号：EP0983983B1

公开(公告)日：2001-12-12

申请号：EP99203631.9

申请日：1997-07-22

Applicant: Symyx Technologies

Inventor： Weinberg, Henry W. ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  Van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

公开(公告)号：EP0985678A2

公开(公告)日：2000-03-15

申请号：EP99203630.1

申请日：1997-07-22

Applicant: Symyx Technologies (US/US)

Inventor： Weinberg, W. Henry ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07F19/00 ,  C07B61/00

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：EP0985678B1

公开(公告)日：2001-12-05

申请号：EP99203630.1

申请日：1997-07-22

Applicant: Symyx Technologies

Inventor： Weinberg, Henry W. ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

公开(公告)号：EP1146030A2

公开(公告)日：2001-10-17

申请号：EP01201676.2

申请日：1997-07-22

Applicant: Symyx Technologies

Inventor： Weinberg, Henry W. ,  Goldwasser, Isy ,  Turner, Howard ,  Murphy, Vince ,  McFarland, Eric ,  Bouisse, Thomas ,  Van Beek, Johannes ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g. homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g. homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (homogeneous catalysts), but also as additives and therapeutic agents.

Abstract translation: 本发明涉及，除其他外，方法为有机金属化合物和催化剂（E. G.均相催化剂）的合成，筛选和表征。 本发明的方法提供了用于支持和不支持的有机金属化合物和催化剂（E. G.均相催化剂）的库的组合合成，筛选和表征。 本发明的方法可以应用可用于制备和大量的有机金属化合物的筛选不仅作为催化剂（均相催化剂），所以但作为添加剂和治疗剂。

公开(公告)号：EP0978499B1

公开(公告)日：2001-11-14

申请号：EP99203632.7

申请日：1997-07-22

Applicant: Symyx Technologies

Inventor： Weinberg, Henry W. ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  Van Beek, Johannes A M ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F19/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

公开(公告)号：EP0983983A2

公开(公告)日：2000-03-08

申请号：EP99203631.9

申请日：1997-07-22

Applicant: Symyx Technologies (US/US)

Inventor： Weinberg, W. Henry ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  Van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F19/00

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：EP0978499A2

公开(公告)日：2000-02-09

申请号：EP99203632.7

申请日：1997-07-22

Applicant: Symyx Technologies (US/US)

Inventor： Weinberg, W Henry ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  Van Beek, Johannes A M ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F19/00

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

Abstract translation: 用于合成，筛选和表征有机金属化合物和催化剂（例如均匀催化剂）的方法，包括组合合成，载体和未负载的有机金属化合物和催化剂（例如均相催化剂）文库的筛选和表征。 该方法可用于大量有机金属化合物的制备和筛选，不仅可用作催化剂（如均相催化剂），还可用作添加剂和治疗剂。

公开(公告)号：EP1146030A3

公开(公告)日：2006-12-27

申请号：EP01201676.2

申请日：1997-07-22

Applicant: SYMYX TECHNOLOGIES

Inventor： Weinberg, Henry W. ,  Goldwasser, Isy ,  Turner, Howard ,  Murphy, Vince ,  McFarland, Eric ,  Bouisse, Thomas ,  Van Beek, Johannes ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C08F10/00 ,  G01N21/64 ,  C40B40/16

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g. homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g. homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (homogeneous catalysts), but also as additives and therapeutic agents.

公开(公告)号：EP0985678A3

公开(公告)日：2000-07-05

申请号：EP99203630.1

申请日：1997-07-22

Applicant: Symyx Technologies (US/US)

Inventor： Weinberg, Henry W. ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.

Abstract translation: 有机金属化合物和催化剂（例如均相催化剂）的合成，筛选和表征的方法学，包括组合合成，筛选和表征负载和未负载的有机金属化合物和催化剂（例如均相催化剂）文库。 该方法可用于大量有机金属化合物的制备和筛选，其不仅可以用作催化剂（例如均相催化剂），还可以用作添加剂和治疗剂。

公开(公告)号：EP0983983A3

公开(公告)日：2000-07-05

申请号：EP99203631.9

申请日：1997-07-22

Applicant: Symyx Technologies (US/US)

Inventor： Weinberg, Henry W. ,  McFarland, Eric ,  Goldwasser, Isy ,  Boussie, Thomas ,  Turner, Howard ,  Van Beek, Johannes A. M. ,  Murphy, Vince ,  Powers, Timothy

IPC: C07B61/00 ,  C07F15/00 ,  C07F15/04 ,  C07F19/00 ,  C08F10/00 ,  G01N21/64

CPC classification number: G01N29/348 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00364 ,  B01J2219/00378 ,  B01J2219/0043 ,  B01J2219/00443 ,  B01J2219/00497 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00515 ,  B01J2219/0052 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/00738 ,  B01J2219/00745 ,  B01J2219/0075 ,  B01J2219/00754 ,  C07F15/0066 ,  C07F15/045 ,  C08F10/00 ,  C08F110/02 ,  C40B40/18 ,  C40B60/14 ,  G01N29/0681 ,  G01N29/2418 ,  G01N2291/106 ,  Y10T436/2575 ,  C08F4/7006 ,  C08F4/027 ,  C08F2500/03 ,  C08F4/7081

Abstract: Methodologies for the synthesis, screening and characterisation of organometallic compounds and catalysts (eg homogenous catalysts), including combinatorial synthesis, screening and characterisation of libraries of supported and unsupported organometallic compounds and catalysts (eg homogenous catalysts). The methods can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (eg homogeneous catalysts), but also as additives and therapeutic agents.