公开(公告)号：EP1289657A2

公开(公告)日：2003-03-12

申请号：EP01932790.7

申请日：2001-04-30

申请人： Symyx Technologies, Inc.

发明人： MANSKY, Paul ,  TIEDE, Richard ,  HAVADTOY, Steve

IPC分类号： B01L3/00

CPC分类号： B01L3/5023 ,  B01J19/0046 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00484 ,  B01J2219/00585 ,  B01J2219/00659 ,  B01J2219/00704 ,  B01L3/50255 ,  B01L2400/0481 ,  B01L2400/049 ,  G01N33/36 ,  G01N33/367 ,  G01N35/028

摘要： An apparatus for use in testing a plurality of compositions in parallel. The apparatus includes an upper plate having a plurality of openings extending therethrough to form upper fluid chambers and a lower plate having a plurality of openings extending at least partially therethrough to form cavities. A central plate having a plurality of openings extending therethrough to form central fluid chambers is positioned between the upper and lower plates with the central chambers in alignment with the upper chambers and the cavities. A porous sheet is interposed between the upper and central plates such that an upper surface of the sheet is in contact with fluid within the upper chamber and a lower surface of the sheet is in contact with fluid within the central chamber. The apparatus further includes a flexible membrane positioned between the lower and central plates such that changes in pressure within the cavities or fluid chambers cause deflection of the membrane to force fluid to pass through the porous sheet.

公开(公告)号：EP1296754A2

公开(公告)日：2003-04-02

申请号：EP01939863.5

申请日：2001-06-01

申请人： SYMYX TECHNOLOGIES

发明人： NIELSEN, Ralph, B. ,  SAFIR, Adam ,  TIEDE, Richard ,  MCWAID, Thomas, Harding ,  VANERDEN, Lynn

IPC分类号： B01J2/00

CPC分类号： B01F15/00207 ,  B01F7/00258 ,  B01F7/00266 ,  B01F7/00291 ,  B01F7/00416 ,  B01F7/00575 ,  B01F7/167 ,  B01F2215/0037 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00308 ,  B01J2219/00335 ,  B01J2219/00337 ,  B01J2219/00342 ,  B01J2219/00353 ,  B01J2219/00373 ,  B01J2219/00389 ,  B01J2219/00418 ,  B01J2219/00477 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00601 ,  B01J2219/00689 ,  B01J2219/00698 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14

摘要： Parallel semi-continuous or continuous reactors are disclosed. The parallel reactors preferably comprise four or more reaction vessels. The reaction vessels are preferably small volume reaction vessels, preferably pressure reaction vessels, and/or preferably integral with a common reactor block. The reaction vessels can comprise shaft-driven stirrers. At least two, preferably at least three or at least four liquid feed lines can provide selective fluid communication between each of the reaction vessels and one or more liquid reagent sources. Additional features, suitable in connection with parallel reactors or with single reaction vessels are also disclosed.

摘要翻译： 公开了平行半连续或连续反应器。 平行反应器优选包含四个或更多个反应容器。 反应容器优选是小容量反应容器，优选压力反应容器，和/或优选与普通反应器块一体化。 反应容器可以包括轴驱动的搅拌器。 至少两个，优选至少三个或至少四个液体供给管线可以提供每个反应容器与一个或多个液体试剂源之间的选择性流体连通。 还公开了适用于平行反应器或单反应容器的附加特征。

公开(公告)号：EP1144107A2

公开(公告)日：2001-10-17

申请号：EP99964099.8

申请日：1999-12-03

申请人： Symyx Technologies, Inc.

发明人： FREITAG, Christopher, J. ,  HAJDUK, Damian ,  NIELSEN, Ralph, B. ,  SAFIR, Adam ,  TIEDE, Richard

IPC分类号： B01J19/00

CPC分类号： B01J19/0046 ,  B01J2219/0029 ,  B01J2219/00308 ,  B01J2219/0031 ,  B01J2219/00313 ,  B01J2219/00315 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/00481 ,  B01J2219/00484 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00691 ,  B01J2219/0072 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  Y10S526/92 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

摘要： A method and apparatus (10) for reacting a plurality of different mixtures in parallel in a semi-batch or continuous mode is provided. Each reaction is contained within a reactor vessel (102), the reactor vessels (102) combined into a reactor block (100). Reactant(s) to be added during the reaction are kept in a header barrel (202), which has a plunger (402) to feed reactant(s) from the header barrel (202) through a transfer line (302) into the reactor vessel (102). The plunger (402) is moved using a drive system (500). The header barrels (202) are optionally combined in a header block (200). The header block (200) is sealed to a plate (300) containing the transfer lines (302), which in turn is sealed to the reactor block (100). A latch mechanism (600) is provided for easy sealing of the reactor (100) and header blocks (200) to the plate (300). The entire apparatus (10) may be placed on a rocker or rotating plate for mixture as the reaction is proceeding.