公开(公告)号：EP2255724A1

公开(公告)日：2010-12-01

申请号：EP10163395.6

申请日：2010-05-20

申请人： SYSMEX CORPORATION

发明人： Asakura, Yoshihiro ,  Kojima, Junko ,  Sato, Toshiyuki

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/1451 ,  A61B5/14514 ,  A61B10/0045 ,  A61B2010/008 ,  A61B2562/0295

摘要： A method for analyzing an analyte in tissue fluid is disclosed. The method comprises: placing a collecting member in contact with the skin of a subject, wherein the collecting member is configured to collect and retain tissue fluid containing the analyte from the subject; collecting tissue fluid from the subject into the collecting member; detaching the collecting member from the skin of the subject; causing the analyte in the tissue fluid collected by the collecting member to diffuse in a liquid by supplying the collecting member with the liquid; and detecting the analyte diffused in the liquid.
An analyzer for analyzing an analyte in tissue fluid, and cartridge and kit for use in the analyzing method are also disclosed.

摘要翻译： 一种用于在组织液分析物的分析方法，是游离缺失盘。 该方法包括：放置一个收集件与受试者的皮肤接触，worin收集件被配置为收集和保留组织液含有来自受试者的分析物; 从受试者到收集部件收集组织液; 分离从受试者的皮肤收集件; 使分析物在通过收集件通过供给与液体回收构件扩散在液体中收集的组织液; 和检测在液体中扩散的分析物。 在组织液分析物的分析和盒和试剂盒中的分析方法中使用的分析仪是这样游离缺失盘。

公开(公告)号：EP1839570A2

公开(公告)日：2007-10-03

申请号：EP07006537.0

申请日：2007-03-29

申请人： SYSMEX CORPORATION

发明人： Maekawa, Yasunori ,  Sato, Toshiyuki ,  Sawa, Kenichi ,  Okada, Seiki ,  Hagino, Kei ,  Asakura, Yoshihiro ,  Ohnishi, Yasuhito

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/14514

摘要： The present invention is to present an analyzer for analyzing a concentration of a predetermined component contained in tissue fluid of a subject, the analyzer being capable of mitigating the pain of the subject. The analyzer comprises: an extraction medium retainer for retaining an extraction medium for holding tissue fluid extracted through a skin of a subject; a component amount information obtainer for obtaining component amount information regarding amount of a predetermined component contained in the tissue fluid held in the extraction medium; an electrical information obtainer for obtaining electrical information related to amount of the extracted tissue fluid by supplying electrical power to the extraction medium which is holding the extracted tissue fluid; and a component concentration obtainer for obtaining a concentration of the predetermined component contained in body fluid of the subject based on the component amount information and the electrical information.

摘要翻译： 本发明提供一种用于分析被检体的组织液中所含有的预定成分的浓度的分析装置，该分析装置能够减轻被检体的疼痛。 分析仪包括：提取介质保持器，用于保持用于保持通过被检体的皮肤提取的组织液的提取介质; 组分量信息获取器，用于获得关于包含在所述提取介质中保持的组织液中的预定成分的量的成分量信息; 电信息获取器，用于通过向正在保存所提取的组织液的提取介质提供电力来获得与所提取的组织液的量相关的电信息; 以及组分浓度获取器，用于基于组分量信息和电信息获得包含在对象体液中的预定成分的浓度。

公开(公告)号：EP2198774B1

公开(公告)日：2018-09-26

申请号：EP09015799.1

申请日：2009-12-21

申请人： SYSMEX CORPORATION

发明人： Okada, Seiki ,  Asakura, Yoshihiro ,  Sato, Toshiyuki ,  Hagino, Kei ,  Kojima, Junko ,  Kikkawa, Yasuo

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/1486

CPC分类号： A61B5/14532 ,  A61B5/14514 ,  A61B5/14865 ,  A61B5/7242 ,  A61B2562/0295

摘要： An in vivo component measurement method comprises steps of: extracting a tissue fluid from a biological body into an extraction medium and accumulating an objective component and an inorganic ion in the extracted tissue fluid; acquiring ion information on a quantity of the accumulated inorganic ion; acquiring a component information on a quantity of the accumulated objective component; and acquiring an analysis value on the quantity of the objective component based on the ion information and the component information.

公开(公告)号：EP2239000A2

公开(公告)日：2010-10-13

申请号：EP10002254.0

申请日：2010-03-04

申请人： Sysmex Corporation

发明人： Asakura, Yoshihiro

IPC分类号： A61M5/42 ,  A61B5/15 ,  A61B5/00

CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/150969

摘要： A system for measuring analytes in a living body comprising: a micropore forming device for forming a micropore on the skin, a guide member mounted on one end of the micropore forming device, a marking member for indicating a position on the skin on which micropores are formed, a collecting member for collecting tissue fluid from the skin via micropores, and a measuring apparatus for measuring analytes in a living body contained in the tissue fluid collected by the collecting member, is disclosed.
A kit for a micropore forming device and a marking member are also disclosed.

摘要翻译： 一种用于测量分析物在生物体内的系统，包括：一个微孔形成在皮肤上的微孔形成装置，导向构件安装在所述微孔形成装置，标记构件，用于指示在皮肤上的微孔的位置的一个端部 形成时，收集件用于从经由微孔皮肤收集组织液，以及用于包含在由所述收集部件所收集的组织液中的生物体测量分析物的测量装置游离缺失盘。 一种用于微孔形成装置和标记试剂盒构件是如此游离缺失盘。

公开(公告)号：EP2198774A1

公开(公告)日：2010-06-23

申请号：EP09015799.1

申请日：2009-12-21

申请人： SYSMEX CORPORATION

发明人： Okada, Seiki ,  Asakura, Yoshihiro ,  Sato, Toshiyuki ,  Hagino, Kei ,  Kojima, Junko ,  Kikkawa, Yasuo

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/14514 ,  A61B5/14865 ,  A61B5/7242 ,  A61B2562/0295

摘要： An in vivo component measurement method comprises steps of: extracting a tissue fluid from a biological body into an extraction medium and accumulating an objective component and an inorganic ion in the extracted tissue fluid; acquiring ion information on a quantity of the accumulated inorganic ion; acquiring a component information on a quantity of the accumulated objective component; and acquiring an analysis value on the quantity of the objective component based on the ion information and the component information.

摘要翻译： 体内成分测定方法包括以下步骤：将组织液从生物体提取到提取介质中，并将提取的组织液中的目标成分和无机离子聚集; 获取关于所累积的无机离子的量的离子信息; 获取关于所累积的目标分量的分量信息; 并且基于离子信息和分量信息获取对目标分量的分析值。

公开(公告)号：EP1839570A3

公开(公告)日：2007-11-21

申请号：EP07006537.0

申请日：2007-03-29

申请人： SYSMEX CORPORATION

发明人： Maekawa, Yasunori ,  Sato, Toshiyuki ,  Sawa, Kenichi ,  Okada, Seiki ,  Hagino, Kei ,  Asakura, Yoshihiro ,  Ohnishi, Yasuhito

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/14514

摘要： The present invention is to present an analyzer for analyzing a concentration of a predetermined component contained in tissue fluid of a subject, the analyzer being capable of mitigating the pain of the subject. The analyzer comprises: an extraction medium retainer for retaining an extraction medium for holding tissue fluid extracted through a skin of a subject; a component amount information obtainer for obtaining component amount information regarding amount of a predetermined component contained in the tissue fluid held in the extraction medium; an electrical information obtainer for obtaining electrical information related to amount of the extracted tissue fluid by supplying electrical power to the extraction medium which is holding the extracted tissue fluid; and a component concentration obtainer for obtaining a concentration of the predetermined component contained in body fluid of the subject based on the component amount information and the electrical information.

公开(公告)号：EP1623665A1

公开(公告)日：2006-02-08

申请号：EP05016767.5

申请日：2005-08-02

申请人： SYSMEX CORPORATION

发明人： Hagino, Kei ,  Maekawa, Yasunori ,  Sawa, Kenichi ,  Okada, Seiki ,  Sato, Toshiyuki ,  Asakura, Yoshihiro

IPC分类号： A61B5/00 ,  A61N1/30

CPC分类号： A61B5/681 ,  A61B5/0531 ,  A61B5/14514 ,  A61B5/14532 ,  A61N1/30

摘要： An analyzer (1) including an electrical information acquiring section (5,6,7,11,12,16,17) for acquiring an electrical information, preferably conductivity, by supplying an electricity to a skin of a subject; an extracting device (2) for extracting a tissue fluid via the skin of the subject; and a controller (10) which calculates a speed at which an analyte is extracted into the extracting device and converts the calculated analyte-extracting speed into a concentration of the analyte included in the tissue fluid in a body of the subject based on the electrical information acquired by the electrical information acquiring section is disclosed. An analyzing method and a blood-sugar level measuring device are also disclosed.

摘要翻译： 一种分析器（1），包括电信息获取部分（5,6,7,11,12,16,17），用于通过向对象的皮肤供电来获取电信息，优选地导电性; 提取装置（2），用于经由被检体的皮肤提取组织液; 以及控制器（10），其计算分析物被提取到所述提取装置中的速度，并且基于所述电信息将所计算的分析物提取速度转换为包含在所述对象体内的所述组织液中的分析物的浓度 公开了由电子信息获取部分获取的信息。 还公开了分析方法和血糖水平测量装置。

公开(公告)号：EP2298177B1

公开(公告)日：2020-12-02

申请号：EP10176373.8

申请日：2010-09-13

申请人： SYSMEX CORPORATION

发明人： Okada, Seiki ,  Asakura, Yoshihiro ,  Takezaki, Akihito ,  Isobe, Kazuki

IPC分类号： A61B10/00 ,  A61B5/145

公开(公告)号：EP2298177A3

公开(公告)日：2012-12-05

申请号：EP10176373.8

申请日：2010-09-13

申请人： SYSMEX CORPORATION

发明人： Okada, Seiki ,  Asakura, Yoshihiro ,  Takezaki, Akihito ,  Isobe, Kazuki

IPC分类号： A61B10/00 ,  A61B5/145

CPC分类号： A61B10/0045 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1477 ,  A61B2010/008

摘要： A interstitial fluid collection kit for collecting interstitial fluid extracted via micropores formed in a skin is disclosed. The kit includes a marker sheet (2) that has an adhesive face and that defines a region in which micropores are to be formed; a transparent retention sheet (11) having an adhesive face; and a collecting body (12) that is retained by a part of the adhesive face of the retention sheet (11) and that collects interstitial fluid extracted from the skin.

公开(公告)号：EP2366999A2

公开(公告)日：2011-09-21

申请号：EP11158646.7

申请日：2011-03-17

申请人： SYSMEX CORPORATION

发明人： Asakura, Yoshihiro

IPC分类号： G01N33/487 ,  G01N35/00

CPC分类号： G01N35/00693 ,  G01N21/276 ,  G01N21/78 ,  G01N35/00029

摘要： An apparatus for analyzing a biological component in a test sample, comprising: a mounting part for selectively mounting a calibration cartridge and an analysis cartridge; a detection part for detecting a component included in a control sample accommodated in the calibration cartridge, the component included in the test sample accommodated in the analysis cartridge, and a biological component included in the analysis cartridge; and an analyzing part for analyzing the biological component included in the test sample based on a detection result of the component included in the control sample, a detection result of the component included in the test sample, and a detection result of the biological component included in the test sample detected by the detection part. A cardridge is also disclosed.

摘要翻译： 一种用于分析测试样品中的生物成分的装置，包括：用于选择性地安装校准盒和分析盒的安装部件; 用于检测包含在容纳在校准盒中的控制样品中的组分的检测部分，容纳在分析盒中的测试样品中包括的组分和分析盒中包含的生物成分; 以及分析部，其基于所述对照样品中包含的成分的检测结果，所述测试样品中包含的成分的检测结果和包含在所述检测样品中的生物成分的检测结果，分析包含在所述检测样品中的生物成分 由检测部检测出检测样品。 还披露了一个卡片。