摘要:
The invention discloses immunogenic polypeptides comprising several MAGE-specific antigen epitopes selected from different (i.e. discrete) members of the MAGE protein family, nucleic acids coding therefor, recombinant viruses and/or cells comprising said nucleic acids, and compositions thereof. Methods for eliciting or inducing MAGE-specific immune responses utilizing the aforementioned immunogenic agents are also disclosed.
摘要:
A gp100 molecule useful in modulating the immune system is described. In particular what is described is a nucleotide sequence for a gp100 which has been modified so as to be useful in modulating the immune system. The isolated nucleic acid sequence is described and referred to as gp100M. The corresponding protein, referred to as gp100M, is also described. Applications of the molecules as vaccines are described.