-
公开(公告)号：EP2163896A1
公开(公告)日：2010-03-17
申请号：EP08764208.8
申请日：2008-06-23
IPC分类号： G01N33/53 , A61K39/395 , A61P37/06 , G01N27/62 , G01N30/72 , G01N30/88 , G01N33/15 , G01N33/50
CPC分类号： C07K16/24 , A61K2039/505 , G01N33/6863 , G01N2030/8831 , G01N2333/523 , G01N2800/245
摘要： Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
摘要翻译： 公开了一种诊断移植物抗宿主病的方法，包括测量从受试者获得的样品中CCL8蛋白的水平，作为移植物抗宿主病的诊断或过程的指标。 还公开了包含抗CCL8抗体的用于移植物抗宿主病的诊断试剂。 本发明的方法能够诊断移植物抗宿主疾病的发作和监测进展，特别是移植物抗宿主疾病与传染病之间的鉴别诊断。 本发明还提供了利用抗CCL8抗体治疗移植物抗宿主病的方法。
-
公开(公告)号：EP2163896B1
公开(公告)日：2013-09-25
申请号：EP08764208.8
申请日：2008-06-23
IPC分类号： C07K16/24 , G01N33/53 , A61K39/395 , A61P37/06 , G01N27/62 , G01N30/72 , G01N30/88 , G01N33/15 , G01N33/50 , G01N33/68
CPC分类号： C07K16/24 , A61K2039/505 , G01N33/6863 , G01N2030/8831 , G01N2333/523 , G01N2800/245
-
搜索结果
2 条记录 (耗时 0.012 秒)
