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公开(公告)号：EP2513533B1
公开(公告)日：2015-09-30
申请号：EP10810876.2
申请日：2010-12-16
IPC分类号： F16K99/00
CPC分类号： F16K99/0001 , B01L3/0265 , B01L3/50273 , B01L3/502738 , B01L2300/0887 , B01L2300/14 , B01L2400/0481 , B01L2400/0487 , B01L2400/0638 , B29L2031/7506 , F15C3/04 , F16K7/123 , F16K7/126 , F16K7/14 , F16K7/17 , F16K99/0015 , F16K99/0034 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084
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公开(公告)号：EP2408561A1
公开(公告)日：2012-01-25
申请号：EP10716615.9
申请日：2010-03-17
CPC分类号： B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L2200/0621 , B01L2200/0652 , B01L2200/0684 , B01L2300/0627 , B01L2300/0816 , B01L2300/087 , B01L2300/1894 , B01L2400/0439 , B01L2400/0487 , B01L2400/06 , F16K99/0015 , F16K2099/008
摘要： A microfluidic system (1) for the isolation of cells (C1) of at least one given type from a sample; the system (1) comprises a separation unit (3), for transferring at least part of the cells (C1) of the given type from a main chamber (4) to a recovery chamber (5) in a substantially selective way with respect to further cells (C2) of the sample; two valves (9, 10) are set upstream and downstream of the main chamber (4); two valves (11, 12) are set upstream and downstream of the recovery chamber (5); a control assembly (23) is designed to govern the aforementioned valves (9, 10, 11, 12); the system (1) proposed enables isolation of the cells with a high degree of reproducibility and precision.
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公开(公告)号：EP2408562B1
公开(公告)日：2018-03-07
申请号：EP10716872.6
申请日：2010-03-17
CPC分类号： B03C5/026 , B01L3/502738 , B01L3/567 , B01L2200/0652 , B01L2300/087 , B01L2300/0877 , B01L2400/0424 , B01L2400/0622 , B03C5/005 , B03C2201/02 , B03C2201/26 , C12M47/04 , F16K99/0001 , F16K99/0015 , G01N2015/1081
摘要： A microfluidic system (1) for the isolation of cells (C1) of at least one given type from a sample; the system (1) comprises a separation unit (3), for transferring at least part of the cells (C1) of the given type from a main chamber (4) to a recovery chamber (5) in a substantially selective way with respect to further cells (C2) of the sample; two valves (9, 10) are set upstream and downstream of the main chamber (4); two valves (11, 12) are set upstream and downstream of the recovery chamber (5); a control assembly (23) is designed to govern the aforementioned valves (9, 10, 11, 12); the system (1) proposed enables isolation of the cells with a high degree of reproducibility and precision.
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公开(公告)号：EP2408562A1
公开(公告)日：2012-01-25
申请号：EP10716872.6
申请日：2010-03-17
CPC分类号： B03C5/026 , B01L3/502738 , B01L3/567 , B01L2200/0652 , B01L2300/087 , B01L2300/0877 , B01L2400/0424 , B01L2400/0622 , B03C5/005 , B03C2201/02 , B03C2201/26 , C12M47/04 , F16K99/0001 , F16K99/0015 , G01N2015/1081
摘要： A microfluidic system (1) for the isolation of cells (C1) of at least one given type from a sample; the system (1) comprises a separation unit (3), for transferring at least part of the cells (C1) of the given type from a main chamber (4) to a recovery chamber (5) in a substantially selective way with respect to further cells (C2) of the sample; two valves (9, 10) are set upstream and downstream of the main chamber (4); two valves (11, 12) are set upstream and downstream of the recovery chamber (5); a control assembly (23) is designed to govern the aforementioned valves (9, 10, 11, 12); the system (1) proposed enables isolation of the cells with a high degree of reproducibility and precision.
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公开(公告)号：EP2513534B1
公开(公告)日：2015-02-25
申请号：EP10812893.5
申请日：2010-12-16
IPC分类号： F16K99/00
CPC分类号： F16K99/0001 , F16K99/0015 , F16K99/0059 , F16K2099/0074 , Y10T137/9247
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公开(公告)号：EP2408560A2
公开(公告)日：2012-01-25
申请号：EP10716034.3
申请日：2010-03-17
CPC分类号： B03C5/026 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L2200/0621 , B01L2200/0631 , B01L2200/0652 , B01L2300/0627 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/14 , B01L2300/1822 , B01L2400/0433 , B01L2400/0487 , B01L2400/0655 , B03C2201/02 , B03C2201/26
摘要： A microfluidic system (1) for the isolation of cells (C1) of at least one given type from a sample; the system (1) comprises a separation unit (3), - for transferring at least part of the cells (Cl) of the given type from a main chamber (4) to a recovery chamber (5) in a substantially selective way with respect to further cells (C2) of the sample; two valves (9, 10) are set upstream and downstream of the main chamber (4); two valves (11, 12) are set upstream and downstream of the recovery chamber (5); a control assembly (23) is designed to govern the aforementioned valves (9, 10, 11, 12); the system (1) proposed enables isolation of the cells with a high degree of reproducibility and precision.
摘要翻译： 一种用于从样品中分离至少一种给定类型的细胞（C1）的微流体系统（1） 所述系统（1）包括分离单元（3），用于以基本上选择性的方式将所述给定类型的至少部分单元（C1）从主室（4）传送到回收室（5） 到另外的样品的细胞（C2）; 两个阀（9,10）设置在主室（4）的上游和下游; 两个阀（11,12）设置在回收室（5）的上游和下游; 控制组件（23）被设计成控制上述阀（9,10,11,12）; 所提出的系统（1）能够以高度的再现性和精度隔离电池。
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公开(公告)号：EP2344624B1
公开(公告)日：2014-04-30
申请号：EP09756171.6
申请日：2009-10-01
IPC分类号： C12M1/42
CPC分类号： B01L3/502753 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2300/0851 , B01L2400/0409 , C12M47/04 , G01N1/4077 , G01N2015/0288
摘要： A sorting chamber (1) for sorting first particles (25) from second particles (26) comprising: an internal chamber (7), which is delimited by a base wall (2), a top wall (4), and a spacer (6), set between the base wall (2) and the top wall (4); an internal chamber (7), which is at least partially-delimited by the base wall (2) and top wall (4); two passages (8), which set in communication the internal chamber (7) with the external environment; and a plurality of cavities (9), which are designed to house the first particles (25), are made in the base wall (2) and have openings (10) towards the internal chamber (7) with widths of from 4 to 6 μm.
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公开(公告)号：EP2513534A1
公开(公告)日：2012-10-24
申请号：EP10812893.5
申请日：2010-12-16
IPC分类号： F16K99/00
CPC分类号： F16K99/0001 , F16K99/0015 , F16K99/0059 , F16K2099/0074 , Y10T137/9247
摘要： A micro- fluidic system (1) comprising a micro- fluidic channel (2), which has a wall (7) provided with a hole (9); and a closing element (10), which is adapted to cooperate with a partition (12) arranged within the micro- fluidic channel (2) in the area of the hole (9) to isolate or connect two segments (4, 5) of the channel (2); the closing element (10) is made of a photoresist material, in particular a material obtained by the polymerisation of a photopolymerable material.
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公开(公告)号：EP2513533A1
公开(公告)日：2012-10-24
申请号：EP10810876.2
申请日：2010-12-16
IPC分类号： F16K99/00
CPC分类号： F16K99/0001 , B01L3/0265 , B01L3/50273 , B01L3/502738 , B01L2300/0887 , B01L2300/14 , B01L2400/0481 , B01L2400/0487 , B01L2400/0638 , B29L2031/7506 , F15C3/04 , F16K7/123 , F16K7/126 , F16K7/14 , F16K7/17 , F16K99/0015 , F16K99/0034 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084
摘要： A micro- fluidic system (1) comprising a micro-fluidic channel (2), which has a wall (7) provided with a hole (9), within which a closing portion (16) of a closing element (13) extends; when the closing portion (16) is arranged within the micro-fluidic channel (2), the passage of the liquid along the channel (2) is interrupted; by deforming the closing element (13) by suction the closing portion (16) may be lifted and therefore allow the passage of liquid along the micro-fluidic channel (2).
摘要翻译： 一种包括微流体通道（2）的微流体系统（1），微流体通道（2）具有设有孔（9）的壁（7），封闭元件（13）的封闭部分（16）在其中延伸; 当封闭部分（16）布置在微流体通道（2）内时，液体沿着通道（2）的通道被中断; 通过抽吸使封闭元件（13）变形，封闭部分（16）可以被提升并因此允许液体沿着微流体通道（2）通过。
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公开(公告)号：EP2344624A1
公开(公告)日：2011-07-20
申请号：EP09756171.6
申请日：2009-10-01
IPC分类号： C12M1/42
CPC分类号： B01L3/502753 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2300/0851 , B01L2400/0409 , C12M47/04 , G01N1/4077 , G01N2015/0288
摘要： A sorting chamber (1) for sorting first particles (25) from second particles (26) comprising: an internal chamber (7), which is delimited by a base wall (2), a top wall (4), and a spacer (6), set between the base wall (2) and the top wall (4); an internal chamber (7), which is at least partially-delimited by the base wall (2) and top wall (4); two passages (8), which set in communication the internal chamber (7) with the external environment; and a plurality of cavities (9), which are designed to house the first particles (25), are made in the base wall (2) and have openings (10) towards the internal chamber (7) with widths of from 4 to 6 μm.
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