公开(公告)号：EP3215271A4

公开(公告)日：2018-06-13

申请号：EP15856708

申请日：2015-11-03

申请人： MASSACHUSETTS GEN HOSPITAL

发明人： KAPUR RAVI ,  SMITH KYLE C ,  TONER MEHMET

IPC分类号： G01N35/08 ,  A61K35/28 ,  B01L3/00 ,  C12M1/12 ,  C12N5/0787 ,  G01N15/00 ,  G01N15/02 ,  G01N15/06

CPC分类号： B01L3/502761 ,  A61K35/28 ,  B01L3/502715 ,  B01L3/502746 ,  B01L3/502753 ,  B01L3/502776 ,  B01L2200/0631 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/12 ,  B01L2300/0681 ,  B01L2300/0877 ,  B01L2300/185 ,  B01L2400/0409 ,  B01L2400/0415 ,  B01L2400/043 ,  B01L2400/0436 ,  B01L2400/0457 ,  B01L2400/0487 ,  B01L2400/082 ,  G01N1/4077 ,  G01N15/0255 ,  G01N15/0618 ,  G01N15/1484 ,  G01N2001/4088 ,  G01N2015/0053 ,  G01N2015/0065 ,  G01N2015/0288 ,  G01N2015/1486 ,  G01N2015/149 ,  G01N2015/1493

摘要： A microfluidic device includes a particle sorting region having a first, second and third microfluidic channels, a first array of islands separating the first microfluidic channel from the second microfluidic channel, and a second array of islands separating the first microfluidic channel from the third microfluidic channel, in which the island arrays and the microfluidic channels are arranged so that a first fluid is extracted from the first microfluidic channel into the second microfluidic channel and a second fluid is extracted from the third microfluidic channel into the first microfluidic channel, and so that particles are transferred from the first fluid sample into the second fluid sample within the first microfluidic channel.

公开(公告)号：EP3244999A1

公开(公告)日：2017-11-22

申请号：EP16700356.5

申请日：2016-01-12

申请人： Dublin City University

发明人： DUCREE, Jens ,  GLYNN, Macdara ,  NWANKIRE, Charles

IPC分类号： B01L3/00 ,  G01N1/40 ,  G01N15/02

CPC分类号： B01L3/502761 ,  B01L3/5025 ,  B01L3/50273 ,  B01L2200/0652 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2400/0409 ,  G01N15/0272 ,  G01N35/00069 ,  G01N2015/0053 ,  G01N2015/0288

摘要： Microfluidic devices that are configured to use centrifugal forces to bias particles into one or more capture regions based on their individual sizes are described.

公开(公告)号：EP3060905A4

公开(公告)日：2017-08-02

申请号：EP14855272

申请日：2014-10-27

申请人： UNIV MONASH

发明人： NEILD ADRIAN ,  ALAN TUNCAY ,  COLLINS DAVID JOHN

IPC分类号： G01N29/02 ,  B01D21/28 ,  B01L3/00 ,  B03C5/00 ,  B03C5/02 ,  G01N1/40 ,  G01N15/02 ,  G01N15/10 ,  G01N27/44

CPC分类号： B01L3/502715 ,  B01D21/283 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/06 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2400/0424 ,  B01L2400/0433 ,  B01L2400/0436 ,  B01L2400/0496 ,  B03C5/005 ,  B03C5/026 ,  B03C2201/26 ,  G01N15/0255 ,  G01N15/1031 ,  G01N15/1056 ,  G01N27/4473 ,  G01N27/44791 ,  G01N2001/4038 ,  G01N2015/0288 ,  G01N2015/1081

公开(公告)号：EP2877832A4

公开(公告)日：2016-04-20

申请号：EP13823614

申请日：2013-07-29

申请人： ENGENDER TECHNOLOGIES LTD

发明人： SIMPSON MIRIAM CATHER ,  ROHDE CHARLES ALAN

IPC分类号： G01N15/14 ,  F15D1/00 ,  G01N15/02 ,  G01N15/10 ,  G01N21/00 ,  G01N21/64 ,  G01N33/48

CPC分类号： G01N15/1456 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/14 ,  B01L2400/0454 ,  B01L2400/0487 ,  G01N15/1425 ,  G01N15/1427 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/6428 ,  G01N2015/0065 ,  G01N2015/0288 ,  G01N2015/1006 ,  G01N2015/149

摘要： A system for orienting particles in a microfluidic system includes one or more radiation pressure sources arranged to expose particles to radiation pressure to cause the particles to adopt a particular orientation in the fluid. A system for sorting particles in a microfluidic system includes a detection stage arranged to detect at least one difference or discriminate between particles in the fluid flow past the detection stage, and one or more radiation pressure sources past which the particles move sequentially and a controller arranged to switch radiation energy to cause a change in direction of movement of selected particles in the fluid flow to sort the particles. The particles may be biological particles such as spermatazoa. The radiation pressure may be optical pressure and may be from one or more waveguides which may extend across a channel of the microfluidic system.

公开(公告)号：EP2548910A4

公开(公告)日：2015-03-25

申请号：EP11756400

申请日：2011-03-17

申请人： NIPPON CATALYTIC CHEM IND

发明人： OKUDA SUMIO ,  KANZAKI SYUJI ,  ISHIZAKI KUNIHIKO ,  FUJINO SHINICHI ,  NOGI KOZO

IPC分类号： C08J3/12 ,  B01J20/26 ,  B07B1/28 ,  B07B1/46 ,  B07B1/56 ,  B07B9/00 ,  C08F6/00 ,  C08F20/06 ,  C08F120/06 ,  C08F220/06 ,  C08J3/075 ,  C08J3/24

CPC分类号： C08F120/06 ,  B07B1/28 ,  B07B1/54 ,  B07B1/56 ,  B07B13/16 ,  C08F6/008 ,  C08F220/06 ,  C08J3/24 ,  C08J3/245 ,  C08J2300/14 ,  G01N15/0272 ,  G01N2015/0277 ,  G01N2015/0288

摘要： Provided is a method which does not require alteration of the raw materials or high capital investment, and improves and stabilizes the physical property (for example, liquid permeability) of a water absorbent resin by means of a simple technique. A method for producing a water absorbent resin is disclosed, which method includes a polymerization step of polymerizing an aqueous solution of acrylic acid (salt) to obtain a water-containing gel-like crosslinked polymer; a drying step of drying the water-containing gel-like crosslinked polymer to obtain a water absorbent resin powder; a classification step of classifying the water absorbent resin powder; and a surface crosslinking step of surface crosslinking the water absorbent resin powder, wherein in the classification steps that are carried before the surface crosslinking step and/or after the surface crosslinking step, the stretch tension (tension) of the metal sieve mesh used in the classification step is from 35 [N/cm] to 100 [N/cm].

公开(公告)号：EP2127748B1

公开(公告)日：2013-10-16

申请号：EP09290348.3

申请日：2009-05-12

申请人： Commissariat à l'Énergie Atomique et aux Énergies Alternatives

发明人： Le Vot, Sophie ,  Berthier, Jean ,  Rivera, Florence

IPC分类号： B01L3/00 ,  G01N15/02

CPC分类号： B01D43/00 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2400/0463 ,  G01N2015/0288

公开(公告)号：EP2548911A1

公开(公告)日：2013-01-23

申请号：EP11756405.4

申请日：2011-03-17

申请人： Nippon Shokubai Co., Ltd.

发明人： OKUDA, Sumio ,  KANZAKI, Syuji ,  ISHIZAKI, Kunihiko ,  FUJINO, Shinichi ,  NOGI, Kozo

IPC分类号： C08J3/12 ,  B01J20/26 ,  C08F20/06

CPC分类号： C08F120/06 ,  B07B1/28 ,  B07B1/54 ,  B07B1/56 ,  B07B13/16 ,  C08F6/008 ,  C08F220/06 ,  C08J3/24 ,  C08J3/245 ,  C08J2300/14 ,  G01N15/0272 ,  G01N2015/0277 ,  G01N2015/0288

摘要： Provided is a method which does not require alteration of the raw materials or high capital investment, and improves and stabilizes the physical property (for example, liquid permeability) of a water absorbent resin by means of a simple technique. A method for producing a water absorbent resin is disclosed, which method includes a polymerization step of polymerizing an aqueous solution of acrylic acid (salt) to obtain a water-containing gel-like crosslinked polymer; a drying step of drying the water-containing gel-like crosslinked polymer to obtain a water absorbent resin powder; a classification step of classifying the water absorbent resin powder; and a surface crosslinking step of surface crosslinking the water absorbent resin powder, wherein in the classification steps that are carried before the surface crosslinking step and/or after the surface crosslinking step, the stretch tension (tension) of the metal sieve mesh used in the classification step is from 35 [N/cm] to 100 [N/cm].

摘要翻译： 本发明提供不需要原料改变或高投资的方法，通过简单的技术提高并稳定吸水性树脂的物性（例如液体透过性）的方法。 公开了一种生产吸水树脂的方法，该方法包括聚合丙烯酸（盐）水溶液以获得含水凝胶状交联聚合物的聚合步骤; 干燥所述含水凝胶状交联聚合物以获得吸水树脂粉末的干燥步骤; 将吸水性树脂粉末分级的分级步骤; 以及将所述吸水性树脂粉末进行表面交联的表面交联工序，其中，在所述表面交联工序前和/或所述表面交联工序后进行的分级工序中，所述金属筛网的拉伸张力（张力） 分级步骤为35 [N / cm]至100 [N / cm]。

公开(公告)号：EP2156879A3

公开(公告)日：2010-07-07

申请号：EP09012086.6

申请日：2002-10-10

申请人： Aviva Biosciences Corporation

发明人： Yamanishi, Douglas ,  Hujsak, Paul ,  Yang, Zhaohuai ,  Xu, Junquan ,  Wang, Xiaobo ,  Wu, Lei ,  Huang, Mingxian ,  Tao, Guoliang ,  Cheng, Jing

IPC分类号： B01D57/02

CPC分类号： G01N15/05 ,  A61M1/36 ,  A61M1/3618 ,  A61M1/362 ,  A61M1/3679 ,  G01N1/40 ,  G01N15/0272 ,  G01N33/491 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2015/0681

摘要： The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from complex fluid sample. In particular, the enrichment of fetal cells from maternal samples, such as maternal blood samples, can greatly aid in the detection of fetal abnormalities or a variety of genetic conditions. In addition, the present invention recognizes that the enrichment of rare malignant cells for patient samples can in diagnosis, prognosis, and development of therapeutic modalities for patients.

摘要翻译： 本发明认识到许多病症的诊断和预后可以取决于来自复杂液体样品的稀有细胞的富集。 具体而言，母体样本（如母体血液样本）富集胎儿细胞可以极大地帮助检测胎儿异常或各种遗传病症。 另外，本发明认识到，用于患者样品的稀有恶性细胞的富集可以用于患者的诊断，预后和发展治疗模式。

公开(公告)号：EP1837642A3

公开(公告)日：2009-11-25

申请号：EP07008515.4

申请日：2001-10-10

申请人： WYATT TECHNOLOGY CORPORATION

发明人： Kuebler, Sigrid ,  Bennett, James

IPC分类号： G01N21/51 ,  G01N21/25 ,  G01N21/49 ,  G01N15/02

CPC分类号： B01D15/08 ,  B01D15/26 ,  B01D15/265 ,  B01D15/325 ,  B01D15/34 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N15/0205 ,  G01N21/253 ,  G01N21/51 ,  G01N21/532 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/461 ,  G01N30/466 ,  G01N30/54 ,  G01N30/60 ,  G01N30/6052 ,  G01N30/88 ,  G01N33/44 ,  G01N33/442 ,  G01N35/085 ,  G01N35/1097 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2030/324 ,  G01N2030/625

摘要： Methods, systems and devices are described for rapid characterization and screening of liquid samples to determine properties (e.g., particle size, particle size distribution, molar mass and/or molar mass distribution) thereof with static light scattering and/or dynamic light scattering. The liquid samples can be solutions, emulsions, suspensions or dispersions. One method, includes providing a vessel containing a liquid sample having an exposed surface that defines a gas-liquid sample interface, and analyzing the sample by light scattering methods that include transmitting light through the gas-liquid sample interface into the sample, and detecting light scattered from the sample or from a component thereof. Additional methods are directed to characterizing a plurality of liquid samples or components thereof. The methods, systems, and devices have applications in high-throughput screening, and particularly, in combinatorial materials research and in industrial process control.

公开(公告)号：EP1683584A3

公开(公告)日：2008-11-12

申请号：EP06075971.9

申请日：2003-08-19

申请人： HEMLOCK SEMICONDUCTOR CORPORATION

发明人： Arvidson, Arvid Neil ,  Graham, Todd Stanley ,  Messner, Kathryn Elizabeth ,  Schmidt, Chris Tim ,  Horstman, Terence Lee

IPC分类号： B07B13/02 ,  B07B13/04 ,  C30B15/02 ,  C30B29/06

CPC分类号： G01N15/0272 ,  B07B13/02 ,  B07B13/04 ,  C30B15/02 ,  G01N2015/0288

摘要： A rotary indent classifier for processing polycristalline silicon workpieces includes: (i) a rotating cylinder having a circumferential edge with indents arrayed in increasing size from a first end of the cylinder to a second end of the cylinder, and (ii) a conveyor running longitudinally adjacent the cylinder, for conveying silicon pieces from the first end of the cylinder to the second end of the cylinder.

摘要翻译： 一种用于处理多晶硅工件以形成适用于切克劳斯基型工艺的多晶硅片的尺寸分布的方法包括：（1）通过化学气相沉积工艺制备多晶硅工件; （2）将多晶硅工件压裂成多晶硅片的混合物，其中多晶硅片具有不同的尺寸; 和（3）将多晶硅片的混合物分选成至少两个尺寸分布。 步骤（2）可以通过热冲击过程进行。 步骤（3）可以使用旋转凹口分类器进行。 一种用于执行该方法的旋转凹口分选机包括：（i）旋转圆筒，其具有沿圆柱体的第一端至第二端的尺寸排列的凹口的圆周边缘，以及（ii）纵向相邻的输送机 气缸，用于将硅片从气缸的第一端输送到气缸的第二端。