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公开(公告)号:EP4081511A1
公开(公告)日:2022-11-02
申请号:EP20830293.5
申请日:2020-12-23
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , COUSIN, David , FYFE, Matthew Colin Thor , WAUGH, Thomas Michael , AHMED, Saleh , DE SIMONE, Alessio , TEOBALD, Barry John
IPC: C07D271/06 , A61K31/4245 , A61P19/02 , A61P29/00
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公开(公告)号:EP4384271A1
公开(公告)日:2024-06-19
申请号:EP22757335.9
申请日:2022-08-11
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , FYFE, Matthew Colin Thor , MAZZACANI, Alessandro
IPC: A61P29/00 , C07C69/593 , C07C233/09 , C07C233/38 , C07D213/30 , C07D233/64 , C07D295/13 , C07D305/08 , C07D309/14 , C07D331/04 , C07D333/16 , A61K31/165 , A61K31/225 , A61K31/337 , A61K31/381
CPC classification number: C07C69/593 , C07D305/08 , C07D213/30 , C07D333/16 , C07C233/09 , C07C233/38 , C07D295/13 , C07D233/64 , C07D331/04 , C07D309/14 , A61P29/00 , C07C2601/0420170501 , C07C233/20 , C07C237/22 , C07B2200/0720130101 , C07C2602/1020170501
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公开(公告)号:EP3962602A1
公开(公告)日:2022-03-09
申请号:EP20723186.1
申请日:2020-04-30
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , COUSIN, David , FYFE, Matthew Colin Thor , TEOBALD, Barry John , THOM, Stephen Malcolm
IPC: A61P29/00 , C07C69/593 , A61K31/19 , A61K31/215 , A61P37/02 , C07C57/13 , C07C69/74 , C07C69/66 , C07D207/267 , C07D211/54 , C07D305/04 , C07D307/06 , C07D309/20 , C07C69/608 , A61K31/194 , C07C69/003 , C07C69/013
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公开(公告)号:EP4442319A3
公开(公告)日:2025-01-15
申请号:EP24183456.3
申请日:2020-12-23
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , COUSIN, David , FYFE, Matthew Colin Thor , WAUGH, Thomas Michael , AHMED, Salah , DE SIMONE, Alessio , TEOBALD, Barry John
IPC: C07D271/06 , A61K31/4245 , A61P19/02 , A61P29/00
Abstract: The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response:
wherein
R A1 , R A2 , R C and R D are as defined herein.-
公开(公告)号:EP4330231A1
公开(公告)日:2024-03-06
申请号:EP22720485.6
申请日:2022-04-26
Applicant: Sitryx Therapeutics Limited
Inventor: FYFE, Matthew Colin Thor , COOKE, Michael Liam , COUSIN, David , AHMED, Saleh , MAZZACANI, Alessandro
IPC: C07D211/96 , C07C235/74 , A61K31/44 , A61P29/00
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公开(公告)号:EP4442319A2
公开(公告)日:2024-10-09
申请号:EP24183456.3
申请日:2020-12-23
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , COUSIN, David , FYFE, Matthew Colin Thor , WAUGH, Thomas Michael , AHMED, Salah , DE SIMONE, Alessio , TEOBALD, Barry John
IPC: A61P29/00
CPC classification number: C07D271/06 , A61P19/02 , A61P29/00
Abstract: The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response:
wherein
RA1, RA2, RC and RD are as defined herein.-
公开(公告)号:EP4200275A2
公开(公告)日:2023-06-28
申请号:EP21759120.5
申请日:2021-08-20
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , FYFE, Matthew Colin Thor , TEOBALD, Barry John
IPC: C07C69/60 , C07D257/04 , A61P29/00 , A61P37/00 , A61K31/225 , A61K31/41 , C07D213/30 , C07D305/08 , C07D331/04 , C07D213/61 , C07D309/10 , C07D333/16 , C07D239/26 , A61K31/351 , A61K31/337 , A61K31/38 , A61K31/381 , A61K31/505
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公开(公告)号:EP3962888A1
公开(公告)日:2022-03-09
申请号:EP20723187.9
申请日:2020-04-30
Applicant: Sitryx Therapeutics Limited
Inventor: COOKE, Michael Liam , COUSIN, David , FYFE, Matthew Colin Thor , TEOBALD, Barry John , THOM, Stephen Malcolm , WAUGH, Thomas Michael
IPC: C07C69/593 , A61P29/00 , A61K31/19 , A61K31/194 , C07C69/003 , C07C69/013 , C07C69/608 , C07C69/66 , C07C69/74 , C07C211/40 , C07C309/12 , C07C309/23 , C07C309/24 , C07C309/27
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公开(公告)号:EP4359390A1
公开(公告)日:2024-05-01
申请号:EP22734668.1
申请日:2022-06-22
Applicant: Sitryx Therapeutics Limited
Inventor: FYFE, Matthew Colin Thor , MAZZACANI, Alessandro , TEOBALD, Barry John , COOKE, Michael Liam , AHMED, Saleh
IPC: C07D241/20 , C07D413/12 , C07D417/12 , A61P29/00 , A61K31/427 , A61K31/4439 , A61K31/497 , A61K31/4965 , C07F9/00 , C07C233/00 , C07D211/58 , C07D213/30 , C07D271/06 , C07D295/13 , C07D305/08 , C07D331/04 , C07D405/04 , C07F9/40
CPC classification number: C07D417/12 , C07D413/12 , C07D241/20 , A61P29/00 , C07F9/4006 , C07D271/06 , C07D331/04 , C07D295/13 , C07D211/58 , C07D213/30 , C07D405/04 , C07D305/08 , C07C235/76 , C07C317/28
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公开(公告)号:EP4192821A1
公开(公告)日:2023-06-14
申请号:EP21752138.4
申请日:2021-08-05
Applicant: Sitryx Therapeutics Limited
Inventor: AHMED, Saleh , COOKE, Michael Liam , FYFE, Matthew Colin Thor
IPC: C07D271/06 , A61P29/00 , A61K31/435 , A61K31/4245
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