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    Multi-channel biopotential signal acquisition systems
    1.
    发明授权
    Multi-channel biopotential signal acquisition systems 有权
    多通道生物电势信号采集系统

    公开(公告)号：EP2442443B8

    公开(公告)日：2018-02-07

    申请号：EP11155072.9

    申请日：2011-02-18

    申请人： IMEC VZW ,  Stichting IMEC Nederland

    发明人： Xu, Jiawei ,  Yazicioglu, Refet Firat

    IPC分类号： H03F3/45 ,  A61B5/04 ,  A61B5/0428

    CPC分类号： A61B5/04004 ,  A61B5/0428 ,  H03F3/45475 ,  H03F3/45928 ,  H03F2200/261 ,  H03F2203/45138

    摘要： Described herein is a multi-channel biopotential signal acquisition system (900) in which a plurality of biopotential channels is corrected for common-mode interference. Each biopotential channel comprises an electrode (910, 920, 930, 940) for providing a biopotential input signal and an associated amplifier (950, 960, 970, 980) for amplifying the biopotential input signal and for providing a biopotential output signal (955, 965, 975, 985) that is processed in a processor (250, 260, 270, 990). Each biopotential output signal (955, 965, 975, 985) is passed to a common-mode feedback system (810) that determines an average common-mode signal and feeds that signal back to each of the amplifiers (950, 960, 970, 980) in each of the biopotential channels to enhance common-mode rejection ratio of the system (900).

    Biopotential signal acquisition system and method
    2.
    发明公开
    Biopotential signal acquisition system and method 审中-公开
    生物分子生物学信号系统

    公开(公告)号：EP3042607A1

    公开(公告)日：2016-07-13

    申请号：EP15150843.9

    申请日：2015-01-12

    申请人： Stichting IMEC Nederland ,  IMEC VZW

    发明人： Xu, Jiawei ,  Yazicioglu, Refet Firat

    IPC分类号： A61B5/04

    CPC分类号： A61B5/04004

    摘要： The invention provides a biopotential signal acquisition system, comprising at least two active electrodes (10,16) each for receiving a signal from an input, for example in the form of a respective patient contact. A unity gain buffer (32) is used to feed forward a signal from an associated input and provide the buffered output to the amplifiers of the active electrodes as a reference signal. The buffered signal is approximately equal to the input common mode signal so that the effective common mode input voltage appearing at the inputs of each amplifier is significantly reduced. This reduces the common mode gain of the active electrodes and thus improves their common mode rejection ratio while also avoiding saturation of the active electrodes.

    摘要翻译： 本发明提供了一种生物电势信号采集系统，其包括至少两个有源电极（10,16），每个用于从输入端接收信号，例如以相应的患者接触的形式。 单位增益缓冲器（32）用于从相关联的输入端提供信号，并将缓冲的输出提供给有源电极的放大器作为参考信号。 缓冲信号近似等于输入共模信号，从而显着降低出现在每个放大器输入端的有效共模输入电压。 这降低了有源电极的共模增益，从而提高了它们的共模抑制比，同时也避免了有源电极的饱和。

    Multi-channel biopotential signal acquisition systems
    3.
    发明公开
    Multi-channel biopotential signal acquisition systems 有权
    ErfassungssystemfürMehrkanal-Biopotenzsignal

    公开(公告)号：EP2442443A1

    公开(公告)日：2012-04-18

    申请号：EP11155072.9

    申请日：2011-02-18

    申请人： IMEC ,  Stichting IMEC Nederland

    发明人： Xu, Jiawei ,  Yazicioglu, Refet Firat

    IPC分类号： H03F3/45 ,  A61B5/04 ,  A61B5/0428

    CPC分类号： A61B5/04004 ,  A61B5/0428 ,  H03F3/45475 ,  H03F3/45928 ,  H03F2200/261 ,  H03F2203/45138

    摘要： Described herein is a multi-channel biopotential signal acquisition system (900) in which a plurality of biopotential channels is corrected for common-mode interference. Each biopotential channel comprises an electrode (910, 920, 930, 940) for providing a biopotential input signal and an associated amplifier (950, 960, 970, 980) for amplifying the biopotential input signal and for providing a biopotential output signal (955, 965, 975, 985) that is processed in a processor (250, 260, 270, 990). Each biopotential output signal (955, 965, 975, 985) is passed to a common-mode feedback system (810) that determines an average common-mode signal and feeds that signal back to each of the amplifiers (950, 960, 970, 980) in each of the biopotential channels to enhance common-mode rejection ratio of the system (900).

    摘要翻译： 这里描述的是多通道生物电位信号采集系统（900），其中多个生物电位通道被校正为共模干扰。 每个生物电位通道包括用于提供生物电位输入信号的电极（910,920,930,940）和用于放大生物电位输入信号的相关放大器（950,960,970,980），并提供生物电位输出信号（955， 965,975,985），其在处理器（250,260,270,990）中处理。 每个生物电势输出信号（955,965,975,985）被传递到共模反馈系统（810），该共模反馈系统确定平均共模信号，并将该信号反馈给每个放大器（950,960,970,985,985,985,985,985） 980），以增强系统的共模抑制比（900）。

    Cardiac monitoring circuit with adaptive sampling
    4.
    发明公开
    Cardiac monitoring circuit with adaptive sampling 有权
    Vorrichtung zur kardialenÜberwachungmit adaptiven Probenentnahme

    公开(公告)号：EP2298164A2

    公开(公告)日：2011-03-23

    申请号：EP10176687.1

    申请日：2010-09-14

    申请人： IMEC ,  Stichting IMEC Nederland

    发明人： Yazicioglu, Refet Firat ,  Penders, Julien ,  Kim, Sunyoung

    IPC分类号： A61B5/0428 ,  A61B5/0456 ,  G01R19/25

    CPC分类号： A61B5/7225 ,  A61B5/04017 ,  A61B5/0402 ,  A61B5/0428 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0531 ,  A61B5/7207 ,  A61B5/7221 ,  A61B5/7228 ,  A61B5/7232 ,  A61B5/7239 ,  G01R19/2509

    摘要： Described herein is an analogue signal processor (ASP) application-specific integrated circuit (ASIC) (400) that can be used for remotely monitoring ECG signals of a subject that has reduced power consumption. The ASP ASIC (400) performs the functions of: ECG signal extraction with high resolution using ECG readout channel (410), feature extraction using a band-power extraction channel (420), adaptive sampling the ECG signals using an adaptive sampling analogue-to-digital converter (440), and impedance monitoring for signal integrity using an impedance monitoring channel (430). These functions enable the development of wireless ECG monitoring systems that have significantly lower power consumption but are more efficient that predecessor systems. The ASP ASIC (400) consumes 30µW from a 2V supply with compression provided by adaptive sampling providing large reductions in power consumption of a wireless ECG monitoring system of whtih the ASP ASIC (400) forms a part.

    摘要翻译： 这里描述了可用于远程监测具有降低的功耗的对象的ECG信号的模拟信号处理器（ASP）专用集成电路（ASIC）（400）。 ASP ASIC（400）执行以下功能：使用ECG读出通道（410）使用高分辨率的ECG信号提取，使用带功率提取通道（420）的特征提取，使用自适应采样模拟到 数字转换器（440），以及使用阻抗监视通道（430）进行信号完整性的阻抗监视。 这些功能使得能够开发具有显着降低功耗的无线ECG监测系统，但是对于前身系统而言更有效。 ASP ASIC（400）从2V电源消耗30μW，通过自适应采样提供压缩，大大降低了ASP ASIC（400）组成的无线ECG监控系统的功耗。

    Multi-channel biopotential signal acquisition systems
    7.
    发明授权
    Multi-channel biopotential signal acquisition systems 有权

    公开(公告)号：EP2442443B1

    公开(公告)日：2017-12-13

    申请号：EP11155072.9

    申请日：2011-02-18

    申请人： IMEC ,  Stichting IMEC Nederland

    发明人： Xu, Jiawei ,  Yazicioglu, Refet Firat

    IPC分类号： H03F3/45 ,  A61B5/04 ,  A61B5/0428

    CPC分类号： A61B5/04004 ,  A61B5/0428 ,  H03F3/45475 ,  H03F3/45928 ,  H03F2200/261 ,  H03F2203/45138

    摘要： Described herein is a multi-channel biopotential signal acquisition system (900) in which a plurality of biopotential channels is corrected for common-mode interference. Each biopotential channel comprises an electrode (910, 920, 930, 940) for providing a biopotential input signal and an associated amplifier (950, 960, 970, 980) for amplifying the biopotential input signal and for providing a biopotential output signal (955, 965, 975, 985) that is processed in a processor (250, 260, 270, 990). Each biopotential output signal (955, 965, 975, 985) is passed to a common-mode feedback system (810) that determines an average common-mode signal and feeds that signal back to each of the amplifiers (950, 960, 970, 980) in each of the biopotential channels to enhance common-mode rejection ratio of the system (900).

    Biopotential signal acquisition system and method
    8.
    发明公开
    Biopotential signal acquisition system and method 有权
    生物电位信号系统和Verfahren

    公开(公告)号：EP2818103A1

    公开(公告)日：2014-12-31

    申请号：EP13173917.9

    申请日：2013-06-27

    申请人： IMEC ,  Stichting IMEC Nederland

    发明人： Xu, Jiawei ,  Yazicioglu, Refet Firat

    IPC分类号： A61B5/04 ,  A61B5/0428 ,  A61B5/0492 ,  A61B5/0408 ,  A61B5/0478 ,  H03F3/45

    CPC分类号： A61B5/7207 ,  A61B5/04004 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/0428 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0496 ,  A61B2562/0209

    摘要： A biopotential signal acquisition system comprises: a first active electrode (10) comprising an integrated pre-amplifier (12) and an analogue to digital converter (14); a second active electrode (16) comprising an integrated preamplifier (18) and an analogue to digital converter (20), wherein the second active electrode has variable gain; a test signal generator (38) for generating a test signal at a test frequency and coupling the test signal to the first and/or second active electrodes (10,16); and a digital signal processor (30) adapted to: process the digital outputs (Vout_ref, Vout1) of the first and second active electrodes (10,16) to derive a gain control signal (D1) based on a difference between the first and second active electrode outputs (Vout_ref, Vout1) at the test frequency, and apply the gain control signal (D1) to the second active electrode (16).

    摘要翻译： 生物电位信号采集系统包括：包括集成前置放大器（12）和模数转换器（14）的第一有源电极（10）; 包括集成前置放大器（18）和模数转换器（20）的第二有源电极（16），其中所述第二有源电极具有可变增益; 测试信号发生器（38），用于在测试频率处产生测试信号，并将测试信号耦合到第一和/或第二有源电极（10,16）; 以及数字信号处理器（30），其适于：处理所述第一和第二有源电极（10,16）的数字输出（Vout_ref，Vout1），以基于所述第一和第二有源电极之间的差导出增益控制信号（D1） 在测试频率处的有源电极输出（Vout_ref，Vout1），并将增益控制信号（D1）施加到第二有源电极（16）。