摘要:
The thiadiazole compound represented by the formula (A) : wherein R 1 represents a C1-C7 alkyl group, a C3-C7 alkenyl group, a C3-C7 alkynyl group and the like; R 2 represents a C1-C4 alkyl group substituted with a hetero ring group in which the hetero ring group may be substituted, which the hetero ring group is a five-membered ring containing only an oxygen atom (s) or a sulfur atom(s) as a hetero atom(s); has an excellent arthropod pests controlling activity.
摘要:
A purpose of the present invention is to provide a method for producing a glycoside compound having a high purity. The present invention provides a method for producing a glycoside compound represented by formula (3) (wherein B a , i-Pr and n are the same as those defined below), which comprises reacting a glycoside compound of formula (1) (wherein B a represents an adenine group which may be optionally substituted with an acyl group, and i-Pr represents an isopropyl group) with an ether compound of formula (2) (wherein R 1 represents a C1-C6 alkyl group or a phenyl group, and n is 0 or 1) in one or more solvents selected from tetrahydropyran and 4-methyltetrahydropyran in the presence of one or more halogenated agents selected from halogen, N-halogenated succinimide, and N-halogenated hydantoin.
摘要:
The present invention provides an amidite compound represented by formula (1) which enables a synthesis of RNA with high purity, and the method for preparing a polynucleotide by using the same compound. (In the formula (1), wherein R represents the following formula (wherein R a and R b are identical to or different from each other and each represents a methyl group, an ethyl group, or a hydrogen atom, with the proviso that R a and R b does not represent a hydrogen atom. n is an integer of 1 to 5), and B a represents a group containing optionally protected nucleobase structure, and G 1 and G 2 are identical to or different from each other and each represents a protecting group for a hydroxy group, and G 3 are identical to or different from each other and each represents an alkyl group.
摘要:
An isoxazoline compound represented by the formula (I): wherein the substituents are as defined in the description, has a controlling activity against pests.
摘要:
A thiadiazole compound represented by the formula (I): wherein R is a hydrogen atom, an optionally substituted C1-C7 chain hydrocarbon group etc., Z is an oxygen atom or a sulfur atom, X is a -NR2R3 group etc., R2 and R3 each independently are a hydrogen atom, a C1-C4 alkyl group, a C3-C4 alkenyl group, a C1-C4 alkoxy group, or a phenyl group, or R2 and R3 bind to each other at the ends thereof to form a C2-C7 alkanediyl group, has excellent controlling effect on a noxious arthropod.
摘要:
1,2,4-Thiadiazole compounds represented by the general formula (1) have excellent control activities against injurious arthropods: (1) wherein R1 is C3-7 alkynyl which may be halogenated; R2 is halogeno, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkylthio, cyano, or nitro, and n is an integer of 0 to 5, with the proviso that when n is an integer of 2 or above, R2s may be the same or different from each other; A is oxygen, sulfur, a single bond, CR3R4, or NR5; R3 and R4 are each independently hydrogen or C1-4 alkyl; and R5 is hydrogen or the like.
摘要:
The present invention provides an amidite compound capable of improving a yield and a purity of a polyoligonucleotide, a glycoside compound as an intermediate thereof, and a production method for a polynucleotide using the amidite compound. The present invention also provides an amidite compound of formula (1) capable of improving a yield and a purity of a polyoligonucleotide, a glycoside compound of formula (10) (in formulae (10) and (1), B a , R a , R b , R c , G 1 , G 2 , and G 3 are as defined in the description, and R is represented by the following formulae), and a production method for a polynucleotide using the amidite compound.
摘要:
The present invention provides a process for preparing a glycoside compound represented by general formula (3), which comprises the following step: Step A: a step of reacting a glycoside compound represented by general formula (1) with an ether compound represented by formula (2) in the presence of an oxidizing agent and an acid to prepare a glycoside compound represented by general formula (3), wherein the oxidizing agent is added to a reaction system, followed by adding an acid thereto (wherein B a represents a cytosine group which may be optionally substituted with acyl group, or an uracil group, R 1 represents a C1 to C6 alkyl group or a phenyl group, and n is 0 or 1), wherein an oxidizing agent is selected from a group consisting of N-halogenated succinimide and N-halogenated hydantoin, and an acid is selected from a group consisting of perfluoroalkylcarboxylic acid and salts thereof, alkylsulfonic acid and salts thereof, arylsulfonic acid and salts thereof, perfluoroalkylsulfonic acid and salts thereof, and any combinations of two kinds or more thereof, which can provide a synthesis of a desired compound (an amidite compound) with high purity.
摘要:
There is provided a hydrazide compound having a controlling effect on pests represented by the formula (1): wherein, G is a 5-membered heterocyclic group, M is an oxygen atom or a sulfur atom, Q 1 , Q 2 , Q 3 and Q 4 is independently a nitrogen atom, etc., m is an integer of 0 to 5, R 2 is an optionally halogenated C1-C6 alkyl group, etc., R 5 and R 6 are independently an optionally substituted C1-C12 chain hydrocarbon group, etc., and R 4 is an optionally substituted C1-C12 chain hydrocarbon group, etc.
摘要:
The present invention relates to a novel 1,2,4-thiadiazole compound represented by the formula (1): wherein, R1 represents C3-C7 alkynyl that may be substituted with halogen atom; R2 represents C3-C8 cycloalkyl which may be substituted with C1-C4 alkyl, halogen atom and trifluoromethyl or the like; A1 represents a single bond, C1-C2 alkylene or C2-C3 alkylidene. The 1,2,4-thiadiazole compound has an excellent arthropod controlling activity, and can effectively control an arthropod pests such as insect pests, acarine pests and the like.