公开(公告)号：EP1997496B1

公开(公告)日：2015-07-29

申请号：EP07738720.7

申请日：2007-03-15

申请人： Suntory Holdings Limited

发明人： TAKEMOTO, Daisuke ,  TATEISHI, Norifumi ,  ONO, Yoshiko ,  SAITO, Kayo ,  MAEDA, Akifumi

IPC分类号： A61K31/525 ,  A23L1/30 ,  A23L1/302 ,  A23L2/52 ,  A61K31/34 ,  A61P25/04 ,  A61P29/00 ,  A61K31/36

CPC分类号： A61K31/525 ,  A23L2/52 ,  A23L33/105 ,  A23L33/15 ,  A23V2002/00 ,  A61K31/34 ,  A61K31/343 ,  A61K31/36 ,  A23V2250/032 ,  A23V2250/708 ,  A23V2250/21 ,  A23V2250/7044 ,  A23V2250/712 ,  A23V2250/5114 ,  A61K2300/00

摘要： The present invention relates to a composition containing riboflavin and a sesamin-class compound(s). This composition may incorporate a sesamin-class compound(s) in such an amount that the proportion (weight ratio) of its total quantity to the total quantity of riboflavin taken as unity is no more than 4.5, and it has the advantage that the analgesic and anti-fatigue actions of riboflavin are synergistically improved by ingestion of riboflavin in combination with a sesamin-class compound(s). The composition of the present invention provides compositions, in particular, pharmaceuticals as well as foods and beverages that are safe to humans, animals, etc. and can therefore be ingested for a continued period, and which have far superior effects to those of conventional foods having an analgesic or anti-fatigue action.

公开(公告)号：EP2135606B1

公开(公告)日：2018-01-24

申请号：EP08721882.2

申请日：2008-03-12

申请人： Suntory Holdings Limited

发明人： ONO, Yoshiko ,  SAITO, Kayo ,  TATEISHI, Norifumi ,  MAEDA, Akifumi

IPC分类号： A61K31/36 ,  A61K36/18 ,  A61P3/02 ,  C07D493/04 ,  A23L33/105

CPC分类号： A23K20/111 ,  A23L33/10 ,  A23L33/105 ,  A23L33/40 ,  A61K31/36 ,  A61K36/185 ,  C07D493/04

摘要： Anti-fatigue agents containing dioxabicyclo[3.3.0]octane derivatives such as sesamin which is an ingredient contained in sesame, as well as pharmaceutical compositions and physiologically functional foods that contain such anti-fatigue agents are disclosed. These compounds can safely be administered to humans and animals alike and hence allow for continued ingestion while proving effective in promoting an improvement of stamina, an increase of body strength, a relief of fatigue, and recovery from fatigue.

公开(公告)号：EP2135606A1

公开(公告)日：2009-12-23

申请号：EP08721882.2

申请日：2008-03-12

申请人： Suntory Holdings Limited

发明人： ONO, Yoshiko ,  SAITO, Kayo ,  TATEISHI, Norifumi ,  MAEDA, Akifumi

IPC分类号： A61K31/36 ,  A23K1/16 ,  A23L1/30 ,  A61K36/18 ,  A61P3/02 ,  C07D493/04

CPC分类号： A23K20/111 ,  A23L33/10 ,  A23L33/105 ,  A23L33/40 ,  A61K31/36 ,  A61K36/185 ,  C07D493/04

摘要： Anti-fatigue agents containing dioxabicyclo[3.3.0]octane derivatives such as sesamin which is an ingredient contained in sesame, as well as pharmaceutical compositions and physiologically functional foods that contain such anti-fatigue agents are disclosed. These compounds can safely be administered to humans and animals alike and hence allow for continued ingestion while proving effective in promoting an improvement of stamina, an increase of body strength, a relief of fatigue, and recovery from fatigue.

摘要翻译： 公开了含有作为芝麻中所含成分的芝麻素的二氧杂二环[3.3.0]辛烷衍生物的抗疲劳剂，以及含有这种抗疲劳剂的药物组合物和生理功能性食品。 这些化合物可以安全地施用于人和动物，因此允许持续摄取，同时证明有效促进体力的提高，身体强度的增加，疲劳的缓解和疲劳的恢复。

公开(公告)号：EP3342409A1

公开(公告)日：2018-07-04

申请号：EP18153048.6

申请日：2008-03-12

申请人： Suntory Holdings Limited

发明人： ONO, Yoshiko ,  SAITO, Kayo ,  TATEISHI, Norifumi ,  MAEDA, Akifumi

IPC分类号： A61K31/36 ,  A61K36/18 ,  A61P3/02 ,  C07D493/04 ,  A23K20/111 ,  A23L33/10

CPC分类号： A23K20/111 ,  A23L33/10 ,  A23L33/105 ,  A23L33/40 ,  A61K31/36 ,  A61K36/185 ,  C07D493/04

摘要： Anti-fatigue agents containing dioxabicyclo[3.3.0]octane derivatives such as sesamin which is an ingredient contained in sesame, as well as pharmaceutical compositions and physiologically functional foods that contain such anti-fatigue agents are disclosed. These compounds can safely be administered to humans and animals alike and hence allow for continued ingestion while proving effective in promoting an improvement of stamina, an increase of body strength, a relief of fatigue, and recovery from fatigue.

公开(公告)号：EP2153831A1

公开(公告)日：2010-02-17

申请号：EP08777022.8

申请日：2008-05-30

申请人： Suntory Holdings Limited

发明人： ASAMI, Sumio ,  SAITO, Kayo ,  MAEDA, Akifumi ,  TATEISHI, Norifumi

IPC分类号： A61K31/365 ,  A23K1/16 ,  A61K31/381 ,  A61K36/18 ,  A61P1/14 ,  A61P3/02 ,  C07D307/58 ,  A23L1/30 ,  A23L2/52

CPC分类号： C07D307/58 ,  A23K20/105 ,  A23K20/121 ,  A23K20/158 ,  A23K50/40 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/18 ,  A23V2200/31 ,  A23V2250/21

摘要： An object is to provide compositions that are safe to humans and animals, can be continually taken on a regular basis, posses anti-fatigue action, and are efficient in preventing or treating fatigue-related illnesses or conditions. The present invention provides anti-fatigue agents that contain andrographolide, optionally in combination with alpha-lipoic acid, as active ingredients, and new oral compositions that contain andrographolide and alpha-lipoic acid. The present invention is useful in preventing or treating chronic fatigue syndrome, overwork, physical fatigue, mental fatigue, and organ fatigue.

摘要翻译： 一个目的是提供对人和动物安全的组合物，可以不断地服用，具有抗疲劳作用，并且有效地预防或治疗与疲劳有关的疾病或病症。 本发明提供了抗疲劳剂，其包含穿心莲内酯，任选地与α-硫辛酸组合作为活性成分，以及含有穿心莲内酯和α-硫辛酸的新型口服组合物。 本发明可用于预防或治疗慢性疲劳综合症，过度劳累，身体疲劳，精神疲劳和器官疲劳。