公开(公告)号：EP1171032A1

公开(公告)日：2002-01-16

申请号：EP00926003.5

申请日：2000-04-14

申请人： Surgi-Vision ,  The Johns Hopkins University

发明人： ATALAR, Ergin ,  BOTTOMLEY, Paul, A. ,  ZERHOUNI, Elias ,  HALPERIN, Henry, R. ,  McVEIGH, Elliott, R. ,  LARDO, Albert, C.

IPC分类号： A61B5/055

CPC分类号： A61B5/415 ,  A61B1/273 ,  A61B1/303 ,  A61B1/307 ,  A61B1/31 ,  A61B5/055 ,  A61B5/418 ,  A61B5/42 ,  A61B5/4381 ,  A61B10/0275 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/3628 ,  H01Q1/36 ,  H01Q1/362 ,  H01Q1/40 ,  H01Q1/44 ,  H01Q11/08

摘要： The system, and methods of the present invention provide for MRI probes (23) adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof, and to treat the diagnosed abnormalities.

公开(公告)号：EP1169749B1

公开(公告)日：2010-05-26

申请号：EP00922135.9

申请日：2000-04-13

申请人： Surgi-Vision ,  The Johns Hopkins University, School of Medicine, Office of Technology Licencing

发明人： LARDO, Albert, C. ,  YANG, Xiaoming ,  ATALAR, Ergin ,  KARMARKAR, Parag ,  McVEIGH, Elliott, R. ,  HALPERIN, Henry, R. ,  McNAMARA, Christine, Enger ,  BOTTOMLEY, Paul, A.

IPC分类号： G01R33/28

CPC分类号： G01R33/287 ,  G01R33/34084

公开(公告)号：EP1169749A2

公开(公告)日：2002-01-09

申请号：EP00922135.9

申请日：2000-04-13

申请人： Surgi-Vision ,  The Johns Hopkins University, School of Medicine, Office of Technology Licencing

发明人： LARDO, Albert, C. ,  YANG, Xiaoming ,  ATALAR, Ergin ,  KARMARKAR, Parag ,  McVEIGH, Elliott, R. ,  HALPERIN, Henry, R. ,  McNAMARA, Christine, Enger ,  BOTTOMLEY, Paul, A.

IPC分类号： H01Q1/00

CPC分类号： G01R33/287 ,  G01R33/34084

摘要： The invention describes a system, method, and means for an MRI guidewire that can be visible on an MRI; can act as an antenna, and receive MRI signals from surrounding subject matter; and can allow the use of multiple interventional tools without removal of the guide wire from a subject. The antenna (106) extends beyond probe shaft (105) at distal end (109). The probe shaft (105) has a core (101), first electric (102), shield (103), and second dielectric (104).

公开(公告)号：EP0898716A1

公开(公告)日：1999-03-03

申请号：EP97918711.0

申请日：1997-04-18

申请人： The Johns Hopkins University

发明人： OCALI, Ogan ,  ATALAR, Ergin

IPC分类号： A61B5 ,  G01R33 ,  A61B10 ,  A61B19

CPC分类号： G01R33/34084 ,  A61B10/0275 ,  A61B2090/374

摘要： The invention provides a method for magnetic resonance imaging and spectroscopic analysis of a specimen which includes positioning the specimen within a main magnetic field and introducing an antenna having a loopless antenna portion in close proximity to the specimen. Radio frequency pulses are provided to the region of interest to excite magnetic resonance signals, gradient magnetic pulses are applied to the region of interest with the antenna receiving magnetic resonance signals and emitting responsive output signals. A processor processes the responsive output signals to provide image information for display in a desired manner. The method in a preferred form involves employing a flexible antenna. The method in another preferred form involves employing an impedance matching circuit electrically interposed between the loopless antenna and the processor to enhance radio frequency power transfer and magnetic resonance signal-to-noise ratio from the loopless antenna to the processor. The method may be used on a wide variety of specimens and in a preferred use is introduced into small blood vessels of a patient to facilitate determination of atherosclerotic plaque. Medical intervention procedures, such as plaque removal, may be employed generally simultaneously with the imaging of the present invention. Corresponding apparatus and magnetic resonance antenna assembly are provided.

公开(公告)号：EP1128765A1

公开(公告)日：2001-09-05

申请号：EP99961661.8

申请日：1999-11-12

申请人： The Johns Hopkins University

发明人： ATALAR, Ergin ,  LESHO, Jeffrey, C. ,  CHARLES, Harry, K., Jr. ,  CARKHUFF, Bliss, G. ,  BOTTOMLEY, Paul, A.

IPC分类号： A61B5/055

CPC分类号： G01R33/34084 ,  G01R33/34007 ,  G01R33/341 ,  G01R33/3657 ,  G01R33/3678

摘要： An electrically insulate generally rectangular flexible circuit board (200) has a first surface (202) on which an electrically conductive path containing a first coil (204) consisting of a first coil segment (210), a generally parallel second coil segment (212), and an end electrically connecting portion (214) are provided. A first capacitor (220), and a second capacitor (222) are provided in the circuit.

公开(公告)号：EP0898716B1

公开(公告)日：2006-08-23

申请号：EP97918711.9

申请日：1997-04-18

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： OCALI, Ogan ,  ATALAR, Ergin

IPC分类号： G01R33/34

CPC分类号： G01R33/34084 ,  A61B10/0275 ,  A61B2090/374

摘要： The invention provides a method for magnetic resonance imaging and spectroscopic analysis of a specimen which includes positioning the specimen within a main magnetic field and introducing an antenna having a loopless antenna portion in close proximity to the specimen. Radio frequency pulses are provided to the region of interest to excite magnetic resonance signals, gradient magnetic pulses are applied to the region of interest with the antenna receiving magnetic resonance signals and emitting responsive output signals. A processor processes the responsive output signals to provide image information for display in a desired manner. The method in a preferred form involves employing a flexible antenna. The method in another preferred form involves employing an impedance matching circuit electrically interposed between the loopless antenna and the processor to enhance radio frequency power transfer and magnetic resonance signal-to-noise ratio from the loopless antenna to the processor. The method may be used on a wide variety of specimens and in a preferred use is introduced into small blood vessels of a patient to facilitate determination of atherosclerotic plaque. Medical intervention procedures, such as plaque removal, may be employed generally simultaneously with the imaging of the present invention. Corresponding apparatus and magnetic resonance antenna assembly are provided.

公开(公告)号：EP1126784A1

公开(公告)日：2001-08-29

申请号：EP99958755.3

申请日：1999-11-04

申请人： The Johns Hopkins University

发明人： HALPERIN, Henry, R. ,  BERGER, Ronald, D. ,  ATALAR, Ergin ,  MCVEIGH, Elliot, R. ,  LARDO, Albert ,  CALKINS, Hugh ,  LIMA, Joao

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system, and method for using magnetic resonance imaging to increase the accuracy of electro-physiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electro-physiologic, an imaging antenna catheter (1) which includes an RF antenna (3) for receiving MR signals, and diagnostic electrodes (11) for receiving electrical potentials. The combined electrophysiology, and imaging antenna catheter (1) is used in combination with an MR imaging scanner to guide, to provide visualization during electro-physiologic diagnostic or therapeutic procedures.

公开(公告)号：EP1038191A1

公开(公告)日：2000-09-27

申请号：EP98958654.0

申请日：1998-11-19

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： ATALAR, Ergin ,  OCALI, Ogan

IPC分类号： G01V3/00

CPC分类号： G01R33/54 ,  G01R33/285 ,  G01R33/34084

摘要： A MRI method that employs cylindrical coordinates uses an elongated catheter (40) which is asociated with an RF pulse transmitting antenna and an RF pulse transmitting body coil (37). Circumferential phase encoding is accomplished by applying an intial RF pulse from either the catheter antenna (40) or the body coil (37) and subsequently applying an initial series of RF pulses with the source alternating between the antenna and the body coil.

公开(公告)号：EP0809810A1

公开(公告)日：1997-12-03

申请号：EP95931684.0

申请日：1995-09-01

申请人： THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE

发明人： ATALAR, Ergin ,  McVEIGH, Elliot, Ross

IPC分类号： G01V3 ,  A61B5 ,  G01R33

CPC分类号： G01R33/4833 ,  G01R33/561

摘要： A method of minimizing dead-periods in magnetic resonance imaging pulse sequences employs a specimen disposed within magnetic field (6), a source of RF signals (2), a receiver (8) for receiving signals from the specimen responsive to RF pulses and emitting respective output signals. A computer (12) is provided for receiving the output signals from the receiver and establishing image information which may be displayed (16). For the dead-period, the minimum and maximum phase encoding step, the scan plane gradient pulse for the slice, phase encoding and readout directions are determined and the moments contained within the dead-period waveform is determined. The values are transformed into gradient amplifier coordinates and the minimum dead-period based on the dead-period waveform is determined. The dead-period is employed in establishing a hardware optimized waveform which may be trapezoidal. The trapezoidal waveform is preferably established by for each phase encoding step determining the starting and ending gradient levels and the moments contained within the dead-period waveform using the calculated minimum dead-period.

公开(公告)号：EP2001367A2

公开(公告)日：2008-12-17

申请号：EP07753178.8

申请日：2007-03-14

申请人： The Johns Hopkins University

发明人： WHITCOMB, Louis, L. ,  KRIEGER, Axel ,  SUSIL, Robert, Charles ,  FICHTINGER, Gabor ,  ATALAR, Ergin ,  IORDACHITA, Ioan, Julian

IPC分类号： A61B8/14

CPC分类号： A61B5/064 ,  A61B5/055 ,  A61B6/12 ,  A61B8/12 ,  A61B10/0241 ,  A61B34/20 ,  A61B34/25 ,  A61B34/30 ,  A61B90/11 ,  A61B90/50 ,  A61B2017/00911 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378

摘要： A device, system, and method for entering a medical device such as a needle into the body inside a medical imager such as a MRI scanner, CT, X-ray fluoroscopy, and ultrasound imaging, from within a body cavity (such as the rectum, vagina, or laparoscopically accessed cavity). A three degree-of-freedom mechanical device translates and rotates inside the cavity and enters a needle into the body, and steers the needle to a target point selected by the user. The device is guided by real-time images from the medical imager. Networked computers process the medical images and enable the clinician to control the motion of the mechanical device that is operated within the imager, outside of the imager or remotely from outside the imager.