公开(公告)号：EP0419676A4

公开(公告)日：1991-09-11

申请号：EP90905649

申请日：1990-03-30

申请人： TEIJIN LIMITED

发明人： HAZATO, ATSUO ,  KATO, YOSHINORI ,  KUROZUMI, SEIZI ,  OHMORI, HITOSHI ,  MINOSHIMA, TORU ,  OSADA, YOSHIO ,  NAGATA, IKUO ,  KOMORIYA, KEIJI

IPC分类号： A61K31/10 ,  A61K31/12 ,  A61K31/19 ,  A61K31/215 ,  A61K31/265 ,  A61K31/27 ,  A61K31/33 ,  C07C317/22 ,  C07C317/44 ,  C07C323/21 ,  C07C323/22 ,  C07C323/52 ,  C07C323/56 ,  C07C323/60 ,  C07D207/32 ,  C07D207/333 ,  C07D213/32 ,  C07D213/50 ,  C07D241/12 ,  C07D257/04 ,  C07D277/26 ,  C07D295/12 ,  C07D333/22 ,  C07D521/00

CPC分类号： C07D207/333 ,  C07C317/22 ,  C07C317/44 ,  C07C323/21 ,  C07C323/22 ,  C07C323/52 ,  C07C323/60 ,  C07D213/32 ,  C07D213/50 ,  C07D241/12 ,  C07D257/04 ,  C07D277/26 ,  C07D333/22

摘要： Thionaphthalene derivatives represented by formula (I) and nontoxic salts thereof, wherein R represents hydrogen, (un)substituted C1 to C5 alkyl, (un)substituted aryl, heterocyclic group, R4CO- (wherein R4 represents (un)substituted C¿1? to C5 alkyl, (un)substituted aryl, or heterocyclic group), R?5¿OCO- (wherein R5 represents hydrogen, (un)substituted C¿1? to C10 alkyl, (un)substituted C3 to C10 alkenyl, or (un)substituted C5 to C7 cycloalkyl), R?6¿NHCO- (wherein R6 represents (un)substituted C¿1? to C5 alkyl, (un)substituted aryl, or heterocyclic group), or cyano; R?1 and R2¿ represent each independently hydrogen, C¿1? to C5 alkyl, or phenyl; R?3¿ represents hydrogen, C¿1? to C5 alkyl, or R?7¿CO- (wherein R7 represents -OR?81, -R82¿, or -NR¿2??83, and R81, R82 and R83¿ represent each C¿1? to C4 alkyl); and n represents an integer of 0 to 2.