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15 条记录 (耗时 0.016 秒)

    APPARATUS FOR ENVIRONMENTAL SIMULATION MEASUREMENT OF WOUND COATING MATERIAL ON THE SKIN AND MEASUREMENT METHOD THEREFOR
    3.
    发明公开
    APPARATUS FOR ENVIRONMENTAL SIMULATION MEASUREMENT OF WOUND COATING MATERIAL ON THE SKIN AND MEASUREMENT METHOD THEREFOR 审中-公开
    设备用于伤口覆盖材料对皮肤及测量方法环境模拟其测定

    公开(公告)号：EP2246690A1

    公开(公告)日：2010-11-03

    申请号：EP08711766.9

    申请日：2008-02-21

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： TAKAHASHI, Makoto ,  OHURA, Takehiko ,  INAMOTO, Yukiko ,  KAMAKURA, Takashi ,  INAMOTO, Shigeyuki

    IPC分类号： G01N15/08

    CPC分类号： G01N15/08 ,  A61B5/445 ,  A61F2013/00944 ,  A61F2013/00953 ,  G01N5/025 ,  G01N19/04

    摘要： There are provided an apparatus and a method for simulatively measuring an environment in a microspace between a human skin and a wound dressing. The simulative environment-measuring apparatus comprises a constant temperature-and-humidity chamber 14 for controlling an external environment; a heat exchanger 12 disposed in the chamber 14; a constant temperature water bath 10 and a pump 11 for supplying warm water to the heat exchanger; and a container 1 which is set on the heat exchanger 12 and is easily detachable therefrom. The container 1 holds a water retentive member 2 therein, and is covered at its upper opening with a water vapor diffusion-controlling member 4. A microspace 6 formed between the water vapor diffusion-controlling member 4 and a wound dressing 5 placed on the member 4 is a simulatively reproduced space between a human skin and the wound dressing 5. A thin temperature-and-humidity sensor 7 is set in this microspace 6 to measure temperature and humidity with time. When plural containers 1 are used, environments of plural wound dressings 5 can be measured at once.

    摘要翻译： 本发明提供的装置和用于在人类皮肤和伤口敷料之间的微小空间的环境模拟地测量的方法。 所述模拟环境测量装置包括一个恒定的温度和湿度的腔室14对外部环境的控制; 在腔室14设置在热交换器12; 一个恒温水浴10和用于供应热水的热交换器的泵11; 和容器1全部被设置在热交换器12和易于从拆离那里。 容器1保持保水性构件2在其内部，并且被覆盖在其与水蒸汽扩散调整构件4的水蒸汽扩散调整构件4和伤口敷料5之间形成的微小空间6放置在构件上上部开口 图4是人的皮肤和伤口敷料5.一种薄温度和湿度传感器7在该微空间6设置为测量温度和湿度与时间之间的模拟地转载空间。 当多个容器1使用时，多个伤口敷料5的环境可以在一次测量。

    ANTI-INFLAMMATORY ANALGESIC ADHESIVE PATCH FOR EXTERNAL USE
    4.
    发明公开
    ANTI-INFLAMMATORY ANALGESIC ADHESIVE PATCH FOR EXTERNAL USE 有权
    ENTZÜNDUNGSHEMMENDESUND SCHMERZSTILLESES HEFTPFLASTER ZUR EXTERNEN ANWENDUNG

    公开(公告)号：EP2524692A1

    公开(公告)日：2012-11-21

    申请号：EP11731785.9

    申请日：2011-01-05

    申请人： Teikoku Seiyaku Co., Ltd. ,  Ibsa Institut Biochimique S.A.

    发明人： SHIBATA, Taiki ,  MABUCHI, Yuichiro ,  HATTORI, Kenichi ,  KAMAKURA, Takashi

    IPC分类号： A61K31/40 ,  A61K9/70 ,  A61K47/10 ,  A61K47/20 ,  A61K47/22 ,  A61K47/32

    CPC分类号： A61K31/40 ,  A61K9/7053 ,  A61K9/7076 ,  A61K31/196 ,  Y10T156/10 ,  A61K2300/00

    摘要： An external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer is characterized by comprising 5-50% by weight of styrene·isoprene·styrene block copolymer, 20-50% by weight of a tackifier resin, 5-70% by weight of a softening agent, and 0.5-20% by weight of one or more solubilizers selected from N-methyl-2-pyrrolidone, propylene glycol and dimethyl sulfoxide as essential ingredients, and 0.5-20% by weight of diclofenac hydroxyethylpyrrolidine as an active ingredient. The patch has excellent transdermal absorption, less skin-irritation and excellent stability of the drug.

    摘要翻译： 通过将粘合剂层层压在背衬上制备的含有双氯芬酸羟乙基吡咯烷的外部贴片，其中所述粘合剂层的特征在于包含5-50重量％的苯乙烯·异戊二烯·苯乙烯嵌段共聚物，20-50重量％的增粘树脂， 5-70重量％的软化剂和0.5-20重量％的一种或多种选自N-甲基-2-吡咯烷酮，丙二醇和二甲基亚砜作为必需成分的增溶剂，和0.5-20重量％ 双氯芬酸羟乙基吡咯烷作为活性成分。 该贴剂具有优异的透皮吸收，较少的皮肤刺激和优异的药物稳定性。

    BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH
    6.
    发明公开
    BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH 有权
    含苯丁胺盐酸盐的水性贴剂

    公开(公告)号：EP2266553A1

    公开(公告)日：2010-12-29

    申请号：EP09730460.4

    申请日：2009-03-24

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： KAMAKURA, Takashi ,  HOSHIKAWA, Takefumi ,  INAMOTO, Yukiko ,  TANIGAWA, Kayo

    IPC分类号： A61K31/137 ,  A61K9/70 ,  A61K47/10 ,  A61K47/14 ,  A61P31/10

    CPC分类号： A61K31/137 ,  A61K8/0208 ,  A61K8/345 ,  A61K8/37 ,  A61K8/41 ,  A61K8/411 ,  A61K9/7053 ,  A61K9/7061 ,  A61K47/10 ,  A61K47/14 ,  A61Q3/00 ,  A61Q17/005

    摘要： An aqueous patch is provided which has excellent storage stability and provides excellent retention of butenafine hydrochloride blended therein onto the application sites such as skin and nails and is highly therapeutic. The butenafine hydrochloride-containing aqueous patch includes butenafine hydrochloride, glycol salicylate, and propylene glycol in a hydrogel paste. Specifically, the butenafine hydrochloride-containing aqueous patch is produced by dissolving butenafine hydrochloride in a mixed solution of glycol salicylate and propylene glycol and dispersing the resulting solution in a hydrogel is provided. In particular, in the butenafine hydrochloride-containing aqueous patch, glycol salicylate and propylene glycol are mixed in a ratio of 1:2 to 1:30.

    摘要翻译： 提供了一种水性贴剂，其具有优异的储存稳定性，并且在其中掺入的布替萘芬盐酸盐优异地保留在皮肤和指甲等施用部位上，并且是高度治疗性的。 含布替萘芬盐酸盐的水性贴剂包括水凝胶糊剂中的盐酸布替萘芬，水杨酸乙二醇酯和丙二醇。 具体而言，通过将布替萘芬盐酸盐溶解在水杨酸乙二醇酯和丙二醇的混合溶液中并将所得溶液分散在水凝胶中来制备含盐酸布替萘芬水性贴剂。 特别地，在含盐酸布替萘芬的水性贴剂中，水杨酸乙二醇酯和丙二醇以1:2至1:30的比例混合。

    WOUND-COVERING HYDROGEL MATERIAL
    9.
    发明公开
    WOUND-COVERING HYDROGEL MATERIAL 有权
    WUNDABDECKUNGS-HYDROGELMATERIAL

    公开(公告)号：EP2246073A1

    公开(公告)日：2010-11-03

    申请号：EP08711928.5

    申请日：2008-02-25

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： KAMAKURA, Takashi ,  SATO, Aki ,  TAKAHASHI, Makoto ,  OHURA, Takehiko

    IPC分类号： A61L15/16

    CPC分类号： A61L15/16 ,  A61L15/26 ,  A61L15/60 ,  C08L75/04

    摘要： A wound-covering hydrogel material which has excellent strechability and absorbs exudates from wounds. It can maintain over long a wet environment which is suitable for accelerating the healing of wounds. There is no fear of causing pain or damaging the regenerated skin when the wound-covering hydrogel material is replaced with a fresh one. The wound-covering hydrogel material prepared by spreading a hydrogel comprising a water-soluble semi-synthetic polymer, glycerol and water, on a laminated two-layer film composed of a polyurethane film and hydrophobic fibers. The covering material has a moisture permeability as measured by the cup method in accordance with JIS Z0208 of 500-2,000(g/m 2 /24h).

    摘要翻译： 一种伤口覆盖的水凝胶材料，具有优异的拉伸性和吸收伤口的渗出物。 它可以保持长时间的潮湿环境，适合加速伤口愈合。 当伤口覆盖的水凝胶材料被新鲜的水凝胶材料替换时，不必担心会引起疼痛或损伤再生皮肤。 通过将包含水溶性半合成聚合物，甘油和水的水凝胶铺展在由聚氨酯膜和疏水纤维构成的层压双层膜上制备的伤口覆盖水凝胶材料。 覆盖材料通过根据JIS Z0208的杯法测量的500-2,000（g / m 2 / 24h）具有的透湿性。