公开(公告)号：EP3192509A4

公开(公告)日：2018-05-16

申请号：EP14901745

申请日：2014-09-12

申请人： TERUMO CORP

发明人： HORIUCHI AIKO ,  SUZUKI SHIGERU

IPC分类号： A61K31/4468 ,  A61K9/08 ,  A61K47/10 ,  A61K47/32

CPC分类号： A61K31/4468 ,  A61K9/0019 ,  A61K9/08 ,  A61K47/10 ,  A61K47/32

摘要： A remifentanil injection solution formulation contains remifentanil and/or physiologically acceptable salts thereof, water, and a stabilizer, the remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025mL per 1mg of said remifentanil.

公开(公告)号：EP3127568A4

公开(公告)日：2017-11-29

申请号：EP15772563

申请日：2015-03-24

申请人： TERUMO CORP

发明人： YOSHIDA AKIRA ,  WATANABE YUKI ,  HORIUCHI AIKO ,  YOSHIKAWA HIROKI

IPC分类号： A61M5/28 ,  A61K31/58 ,  A61M5/315

CPC分类号： A61K31/58 ,  A61K9/0019 ,  A61L31/028 ,  A61L31/048 ,  A61L31/049 ,  A61M5/28 ,  A61M5/3129 ,  A61M5/31511 ,  A61M5/31513 ,  A61M2005/3104 ,  A61M2005/3131

摘要： A rocuronium bromide injection solution-prefilled syringe (1) of the present invention includes a syringe (2) comprising an outer cylinder (21) made of synthetic resin, a gasket (22) which is accommodated inside the outer cylinder (21) and liquid-tightly slidable inside the outer cylinder, and a seal member (23) for sealing a distal end opening of the outer cylinder (21); and a rocuronium bromide injection solution (3) filled inside the syringe (2). The gasket (22) is formed by vulcanized chlorinated butyl rubber added calcined clay, and said calcined clay is only added as an inorganic filler classified as an inorganic reinforcing agent and an inorganic filling agent.

公开(公告)号：EP2226088A4

公开(公告)日：2016-09-07

申请号：EP08866865

申请日：2008-12-26

申请人： TERUMO CORP

发明人： HORIUCHI AIKO ,  WATANABE EIJI ,  SUZUKI SHIGERU ,  SHIMODA MASAMI

IPC分类号： A61M5/315 ,  A61M5/28 ,  A61M5/31

CPC分类号： A61M5/31513 ,  A61M2005/3104 ,  A61M2005/3118 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238

摘要： Disclosed is a gasket, for a syringe, constructed so as to come into slidable contact with a syringe fluid-tightly within an external cylinder of the syringe. The gasket comprises a gasket body formed of an elastic body and a covering layer provided at least in a part, in the gasket body, which comes into contact with the syringe. The covering layer is formed of a composition containing a silicone resin and free from solid fine particles. The silicone resin comprises a condensate of a terminal silanol group-containing reactive silicone and has a siloxane bond derived from the silanol group.

公开(公告)号：EP3192508A4

公开(公告)日：2018-03-07

申请号：EP14901531

申请日：2014-09-12

申请人： TERUMO CORP

发明人： HORIUCHI AIKO ,  HOJO TOMOYUKI

IPC分类号： A61K31/4468 ,  A61K9/00 ,  A61K9/08 ,  A61K9/19 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26

CPC分类号： A61K31/4468 ,  A61K9/0019 ,  A61K9/08 ,  A61K9/19 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26

摘要： A remifentanil injection formulation contains remifentanil and/or physiologically acceptable salts of said remifentanil and a colorant selected from among cyanocobalamin, indocyanine green, and indigocarmine.

公开(公告)号：EP3050591A4

公开(公告)日：2017-05-17

申请号：EP14849980

申请日：2014-09-22

申请人： TERUMO CORP

发明人： HORIUCHI AIKO ,  FUKE SHIGEAKI ,  MORIYAMA YOSHIHISA

IPC分类号： A61M39/10 ,  A61M5/162 ,  A61M5/24 ,  A61M5/28 ,  A61M5/31

CPC分类号： A61M5/3134 ,  A61J1/201 ,  A61J1/2096 ,  A61J2200/10 ,  A61M5/162 ,  A61M2005/3104 ,  A61M2005/3117

摘要： A syringe barrel 3 includes a distal end portion 31, and the distal end portion 31 includes a hollow small-diameter distal end portion 32 having a length of 5 to 6 mm, configured to have a puncture end portion 37 capable of inserting a puncturable portion of other medical device, and a large-diameter portion 33 having an outer diameter of 4.04 to 4.20 mm, larger than that of the small-diameter distal end portion 32, the outer diameter being increased by a 6/100 taper. The distal end portion 31 can puncture the puncturable portion of other medical device, using the small-diameter distal end portion 32, and can be connected to a connection portion of other medical device having a female luer taper, using the large-diameter portion 33.

摘要翻译： 注射器针筒3具有前端部31，前端部31具有长度为5〜6mm的中空的小径的前端部32，该前端部32构成为具有能够插入穿刺部的穿刺端部37 以及外径为4.04〜4.20mm的大直径部33比小直径前端部32大的外径增大6/100锥度。 前端部31能够使用小直径前端部32刺穿其他医疗器具的可穿刺部分，并且能够使用大直径部分33连接到具有母鲁尔锥形的其他医疗装置的连接部分 。

公开(公告)号：EP3042678A4

公开(公告)日：2017-05-10

申请号：EP14842197

申请日：2014-09-03

申请人： TERUMO CORP

发明人： HORIUCHI AIKO ,  HOJO TOMOYUKI ,  OKIHARA HITOSHI

IPC分类号： A61M5/31 ,  A61J1/05 ,  A61M5/24 ,  A61M5/28 ,  A61M5/32 ,  A61M39/20

CPC分类号： A61M5/28 ,  A61M5/3129 ,  A61M5/3135 ,  A61M5/31505 ,  A61M39/20 ,  A61M2005/3104 ,  A61M2005/3106

摘要： Disclosed herein is a syringe barrel (18) of a pre-filled syringe (10), including: a barrel main body (12) having a female luer (23) at its distal end; and a cap (14) that is detachably attached to the female luer (23). In a state where the cap (14) is fixed to the female luer (23) by engagement between a female-side fixing part (26) provided in the female luer (23) and a cap-side fixing part (44) provided in the cap (14), an insertion part (37) provided in the cap (14) is spaced apart from an inner periphery of the female luer (23), and a sealing part (39) provided in the cap (14) is in close contact with a distal end surface of the female luer (23) along an entire circumference of an opening (23b) of the female luer (23).

摘要翻译： 本文公开了预填充注射器（10）的注射器筒（18），其包括：筒主体（12），其远端具有母鲁尔（23） 和可拆卸地连接到母鲁尔（23）上的帽（14）。 在通过设置在母鲁尔（23）中的母侧固定部分（26）和设置在母鲁尔（23）上的盖侧固定部分（44）之间的接合将盖（14）固定到母鲁尔 设置在帽14中的插入部37与母鲁尔23的内周分离，并且设置在帽14中的密封部39处于 与母鲁尔（23）的远端表面沿母鲁尔（23）的开口（23b）的整个圆周紧密接触。