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公开(公告)号：EP1407007A1
公开(公告)日：2004-04-14
申请号：EP02740122.3
申请日：2002-06-14
发明人： BROWNING, Glenn, Francis , PETERS, Michelle, Alma , TIVENDALE, Kelly, Ann , SCOTT, Peter, Christopher , BROWN, Hayley, Kay , CRABB, Brendan, Scott
CPC分类号： C12N7/00 , A61K2039/525 , C12N2750/10061
摘要： An isolated attenuated circovirus having a mutation in viral nucleic acid encoding viral protein 2 (VP2). The attenuated circovirus is particularly suitable for use in conferring immunity in an animal, particularly birds.
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公开(公告)号：EP0655072A1
公开(公告)日：1995-05-31
申请号：EP93909700.0
申请日：1993-05-28
CPC分类号： C07K14/005 , A61K38/00 , A61K39/12 , A61K39/245 , C12N7/00 , C12N2710/16722 , C12N2710/16723 , C12N2710/16734 , Y10S435/975 , Y10T436/143333
摘要： Disclosed are serological assays based on unique sequence type-specifice gG proteins and polypeptides capable of distinguishing the closely related EHV4 and EHV1 viruses. The assays are capable of clearly and unambiguously distinguishing animals infected with EHV4 or EHV1 and thereby distinguishing the EHV4 infection: equine rhinopheumonitis, causing 'snotty noses' from the more dramatic consequences of EHV1 infection; equine abortion, which often results in an 'abortion storm' and high loss of livestock. Further disclosed are the unique type-specific epitopes of EHV4 and EHV1, recombinantly derived novel nucleic acid sequences and proteins which are useful in providing assay reagents, antibodies, vaccines, probes and associated peripherals for diagnosis and control.
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公开(公告)号：EP1407007B1
公开(公告)日：2009-09-30
申请号：EP02740122.3
申请日：2002-06-14
发明人： BROWNING, Glenn, Francis , PETERS, Michelle, Alma , TIVENDALE, Kelly, Ann , SCOTT, Peter, Christopher , BROWN, Hayley, Kay , CRABB, Brendan, Scott
CPC分类号： C12N7/00 , A61K2039/525 , C12N2750/10061
摘要： An isolated attenuated circovirus having a mutation in viral nucleic acid encoding viral protein 2 (VP2). The attenuated circovirus is particularly suitable for use in conferring immunity in an animal, particularly birds.
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4.发明授权Immunological method for the detection of antibodies to equine herpesvirus type 1 and 4 glycoprotein G 失效用于检测马疱疹病毒1型的糖蛋白G和4抗体的免疫学方法
公开(公告)号：EP0655072B1
公开(公告)日：2004-02-11
申请号：EP93909700.2
申请日：1993-05-28
IPC分类号： C12N15/12 , C12N15/70 , C12N1/21 , C07K14/03 , C07K16/08 , G01N33/569 , A61K39/265
CPC分类号： C07K14/005 , A61K38/00 , A61K39/12 , A61K39/245 , C12N7/00 , C12N2710/16722 , C12N2710/16723 , C12N2710/16734 , Y10S435/975 , Y10T436/143333
摘要： Disclosed are serological assays based on unique sequence type-specifice gG proteins and polypeptides capable of distinguishing the closely related EHV4 and EHV1 viruses. The assays are capable of clearly and unambiguously distinguishing animals infected with EHV4 or EHV1 and thereby distinguishing the EHV4 infection: equine rhinopheumonitis, causing 'snotty noses' from the more dramatic consequences of EHV1 infection; equine abortion, which often results in an 'abortion storm' and high loss of livestock. Further disclosed are the unique type-specific epitopes of EHV4 and EHV1, recombinantly derived novel nucleic acid sequences and proteins which are useful in providing assay reagents, antibodies, vaccines, probes and associated peripherals for diagnosis and control.
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